Nurtec ODT® Tablets for Migraine

Nurtec ODT® is a prescription migraine treatment used for acute attacks and prevention in adults. It dissolves on the tongue and can be taken without water. You can compare options, check access details, and see how this page supports ordering with US delivery from Canada and planning costs without insurance.

What Nurtec Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine contains rimegepant, a calcitonin gene-related peptide (CGRP) receptor antagonist. It works by blocking CGRP receptor activity, which may help relieve migraine pain and other symptoms such as light or sound sensitivity. For prevention, regular dosing may reduce how often attacks occur in some adults. The Neurology category offers context on related therapies and conditions.

The Nurtec generic name is rimegepant. The tablet is designed to dissolve on or under the tongue. Swallowing is not required for effect, and water is optional. See broader brain health perspectives in our article World Brain Day for supportive education.

Who It’s For

This treatment is approved for the acute treatment of migraine with or without aura in adults. It is also indicated for the preventive treatment of episodic migraine in adults. It is not approved for children. People with severe liver disease or end-stage kidney disease should avoid use. If you are pregnant, planning pregnancy, or breastfeeding, discuss potential risks and benefits with a healthcare professional before starting.

Learn more about the condition under Migraine. Some life stages can affect symptoms; see our article Menstruation And Migraines for background insights you can bring to your next appointment.

Dosage and Usage

Follow your prescriber’s directions and the official label. For acute treatment, the standard on-label dose is one tablet taken when a migraine attack begins. Do not take more than one dose in 24 hours. For prevention of episodic migraine, the on-label schedule is one tablet every other day.

Administration tips: with dry hands, gently peel back the blister foil to remove the tablet. Place it on or under the tongue and allow it to dissolve. Do not push the tablet through the foil, as this can damage it. Food does not meaningfully affect how it works. Ask your clinician about timing if you also use other acute therapies.

For label-aligned information about how much to take, talk with your prescriber and review the leaflet; this helps tailor the Nurtec ODT dosage to your prescribed plan.

Strengths and Forms

The product is supplied as orally disintegrating tablets in unit-dose blisters. The commonly available presentation is 75 mg. Availability can vary by partner pharmacy and market.

Missed Dose and Timing

For prevention, if you miss a scheduled every-other-day dose, take it when you remember and then continue your usual schedule. Do not take more than one dose in 24 hours. For acute use, take a single dose at the start of an attack; a routine “make-up” dose is not needed if the episode has passed. If timing questions arise with other medicines, consult your prescriber or pharmacist.

Storage and Travel Basics

Store the blisters at room temperature in a dry place, away from excess moisture and light. Keep tablets in the original packaging until you are ready to use one. Wash and dry hands before removing a tablet. For travel, keep the labeled package with your prescription details in your carry-on. A small, protective case can help prevent crushing. If you cross time zones while on a preventive schedule, ask your clinician for simple ways to keep your every-other-day rhythm.

Benefits

This medicine is a CGRP receptor antagonist that can treat acute migraine attacks and, when taken regularly, help prevent episodic migraine. The orally disintegrating format is convenient for people who have nausea or limited access to water during an attack. Many patients appreciate taking a single dose for an episode and a simple every-other-day plan for prevention.

Side Effects and Safety

• Common: nausea, stomach discomfort, indigestion.
• Less common: rash or mild hypersensitivity reactions.
• Rare but serious: severe hypersensitivity, including delayed reactions with breathing problems or swelling; seek urgent care if these occur.

All medicines carry risk. Stop the drug and seek medical help if you develop symptoms of a serious allergic reaction such as hives, trouble breathing, or swelling of the face or throat. Liver problems are uncommon; report yellowing of skin or eyes, dark urine, or unusual fatigue. Read the Medication Guide and ask a healthcare professional if you have questions.

For a concise overview of common Nurtec ODT side effects, review the official prescribing information linked below.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors (for example, certain antifungals or some macrolide antibiotics) can increase exposure to rimegepant; strong CYP3A4 inducers (such as rifampin) can reduce its effect. Some P-gp or BCRP inhibitors may also raise exposure. With certain interacting drugs, a second dose should not be taken within 48 hours; your prescriber will advise based on your medication list.

Avoid grapefruit or grapefruit juice when advised by your clinician. Do not use this treatment in severe hepatic impairment or in end-stage renal disease. Discuss use if you are pregnant or breastfeeding. Always provide a full medication and supplement list to your healthcare professional to help spot potential interactions.

What to Expect Over Time

For acute attacks, some people notice symptom relief after a single dose. Individual responses vary. For prevention, the goal is fewer migraine days over time with steady every-other-day dosing. Keep a simple headache diary to track frequency, triggers, and response. Share those notes during visits so your prescriber can confirm you remain on the right plan. For lifestyle support, see our article Migraine Awareness.

Compare With Alternatives

Two approved options many clinicians consider include a triptan and an NSAID solution. A triptan such as Zolmitriptan is often used at the onset of a migraine; note that triptans can cause vasoconstriction and may not suit everyone. An NSAID powder-in-solution like Cambia® PD Oral Solution can relieve pain in some attacks and may be preferred when a CGRP antagonist is not suitable.

Pricing and Access

We list current options so you can review the Rimegepant price and compare formats. Access may reflect Canadian market rates with US shipping from Canada. Final costs can vary by quantity dispensed and dispensing partner. If you’re looking for available offers, visit our Promotions page for general savings opportunities. Checkout is encrypted for your security.

If you plan ongoing prevention, consider discussing a multi-month fill with your prescriber. That can reduce per-fill fees and simplify refills. Self-pay patients can also set calendar reminders so you never run low before a trip or an important event.

Availability and Substitutions

Supply can vary. If this item is not available, your prescriber may recommend an alternative in the same class or a different class. We will not substitute without a valid prescription directive. Your clinician’s guidance ensures the alternative aligns with your diagnosis, history, and other medicines.

Patient Suitability and Cost-Saving Tips

Good candidates are adults diagnosed with migraine who need an acute option, a preventive plan, or both. People with severe liver disease or end-stage kidney disease should avoid this treatment. Share your full history, including allergies and all current medicines, with your prescriber.

• Multi-month fills: fewer fees and simpler scheduling.
• Set refill reminders: avoid gaps in prevention.
• Travel prep: keep tablets in original blisters.
• Budget planning: review cash-pay options during checkout.

For people managing expenses, discuss quantity and refill timing with your clinician and pharmacist. Questions about coverage can be raised with your insurer; cash-pay options are available at checkout.

Questions to Ask Your Clinician

• Is a CGRP antagonist appropriate for my migraine pattern?
• How should I time doses if I also use a triptan or an NSAID?
• What signs of allergy or intolerance should I watch for?
• Are there medicines or supplements I should avoid?
• If I am planning pregnancy, how should we adjust therapy?
• What is a reasonable goal for fewer migraine days over time?

Authoritative Sources

FDA DailyMed: Rimegepant ODT Prescribing Information

FDA: Approved Labeling Archive

Health Canada Drug Product Database

Ready when you are. Place your order for this medicine today with Ships from Canada to US and prompt, express shipping, with temperature-controlled handling when required. This information is educational and does not replace advice from your healthcare professional.