EGRIFTA® Injection for HIV-Associated Lipodystrophy

Tesamorelin is a prescription growth hormone–releasing factor analog. It is used to reduce excess abdominal fat in adults with HIV-associated lipodystrophy. This page helps you review how the medicine works, who it suits, and how you can arrange US shipping from Canada with clear guidance on pricing, even without insurance.

What EGRIFTA Is and How It Works

EGRIFTA® contains tesamorelin, a peptide that stimulates the pituitary to release growth hormone. That increase can reduce visceral abdominal fat in eligible adults living with HIV. The effect is specific to visceral fat; it is not a general weight-loss treatment. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine is supplied as a powder for subcutaneous use after mixing with the provided diluent. By mimicking endogenous growth hormone–releasing hormone, it triggers physiologic GH pulsatility. The result can help reduce VAT measured by imaging or waist metrics under clinician supervision. Use is ongoing and reassessed by your prescriber based on benefit and safety.

Only inject into recommended areas of the abdomen, avoiding the navel and any irritated skin. Rotate sites to lower the chance of local reactions. An EGRIFTA injection is typically taken once each day at about the same time.

Who It’s For

This treatment is indicated for adults with HIV-associated lipodystrophy who have problematic abdominal visceral adiposity. It is not for weight loss in people without HIV. It should not be used if you are pregnant, have an active cancer, or have disrupted pituitary function due to surgery, radiation, or head injury.

People with diabetes, prediabetes, or risk factors for glucose intolerance require careful monitoring. Those with a history of hypersensitivity to tesamorelin or its excipients should avoid use. Talk with your clinician if you have a strong family history of cancer, carpal tunnel symptoms, or fluid retention concerns. For broader context on HIV care, see HIV resources and related therapies such as those discussed in our Biktarvy Guide.

Dosage and Usage

Follow the official label and your prescriber’s directions. The usual regimen is a once-daily subcutaneous injection into abdominal tissue. Prepare a clean workspace, wash hands, and gather the vial, diluent, syringe, and needle. Reconstitute the powder only as instructed in the patient leaflet. Gently swirl; do not shake. Visually inspect the solution before use.

Clean the skin with an alcohol swab. Pinch a fold of skin and insert the needle as directed. Inject the full dose at a steady pace. Remove the needle and apply light pressure with gauze; do not rub the site. Dispose of needles safely each time. Your prescriber may monitor IGF-1 and glucose periodically while you are using tesamorelin 2mg.

Do not change your dose or schedule without your clinician’s advice. If you have questions about steps, refer to the official patient instructions supplied with your prescription, or consult your healthcare professional.

Strengths and Forms

Availability may vary by supplier. Common presentations include:

• Lyophilized powder vials with sterile diluent, labeled for subcutaneous use
• Single-use vials typically supplied in kits with syringes and alcohol swabs
• Most kits are designed for daily mixing and injection as directed

EGRIFTA SV is a reformulated version designed for simpler reconstitution. The labeled strength is commonly 2 mg per vial. Check your carton for exact components and follow the package insert.

Missed Dose and Timing

If you miss a dose, take the next dose at the regular time. Do not double up to make up for a missed injection. If you are unsure whether to inject, contact your prescriber or pharmacist for guidance. Aim to take each dose at a consistent time each day to support adherence.

Storage and Travel Basics

Follow the storage section on the package insert. Keep the vials in their original carton to protect from light. Do not freeze. Use reconstituted solution only as directed and within the allowed time window on the label. Keep out of reach of children and pets.

When traveling, carry the medicine in your hand luggage with supplies, a copy of your prescription, and a sharps container or approved travel alternative. Use a cooler pack if your label requires refrigeration, and avoid placing vials directly against ice. If airline or security staff have questions, present your prescription and medication label. Our partners use temperature-controlled handling when required.

Pen Handling and Sharps Disposal

This therapy is not supplied as a pen. Use the provided syringes and needles per the instructions. Place used needles and syringes immediately into an FDA-cleared sharps container. When it reaches the fill line, follow local regulations for disposal. Never discard loose sharps into household trash or recycling.

Benefits

As part of HIV care, this class can reduce visceral abdominal fat that contributes to a protuberant abdomen. That change may help clothing fit and comfort. Once-daily timing may be simpler for some routines compared with more complex injection schedules. Treatment does not replace antiretroviral therapy, diet, or activity guidance from your care team.

Side Effects and Safety

Common effects can include:

• Injection site redness or itching
• Swelling in hands or feet
• Joint or muscle pain
• Tingling or numbness
• Headache or nausea
• Rash or mild hives

Serious risks are uncommon but can include hypersensitivity reactions, glucose intolerance or new-onset diabetes, carpal tunnel syndrome, and increased IGF-1. People with active malignancy should not use this medicine. If you notice symptoms of high blood sugar, severe rash, difficulty breathing, or persistent wrist pain, seek medical attention promptly. Report all adverse effects to your prescriber. For broader weight topics, see our Weight Management category; note that this therapy is not a general weight-loss medicine.

Drug Interactions and Cautions

Tell your clinician about all medicines and supplements. Glucocorticoids may oppose the action of the growth hormone pathway. Using other agents that affect glucose could require closer monitoring. Do not combine with somatropin or similar products unless your clinician directs it. Review your history of malignancy, pituitary disease, and pregnancy plans with your prescriber before starting.

Alcohol use may affect glucose control. Continue antiretroviral therapy as prescribed. For additional HIV-related reading, see Aptivus For HIV and our feature on National HIV Testing Day.

What to Expect Over Time

Changes tend to be gradual. Your clinician may use waist measurements, imaging, or other metrics to assess response and determine whether to continue. Adherence to daily injections is important. Report new symptoms promptly, especially signs of glucose changes or carpal tunnel. Avoid injecting into irritated skin and keep rotating sites to limit local reactions. If treatment is paused, visceral fat can return; ongoing assessment with your prescriber helps guide next steps.

Compare With Alternatives

No other medicines are approved specifically to reduce HIV-associated abdominal visceral adiposity. Some patients with different HIV-related body composition concerns may be managed with other endocrine therapies under specialist care. For context only, your clinician may also discuss treatments used for other HIV-associated conditions such as Serostim or growth hormone products like Norditropin FlexPro. These are for different indications; decisions should follow clinical guidelines.

Pricing and Access

We list transparent details so you can compare options and find a tesamorelin price that fits your situation. You can view kit components and vial counts before checkout. If you pay cash, you can estimate your total with your prescriber’s dosing schedule. Our encrypted checkout supports card payments and pharmacy coordination.

Many want to understand tesamorelin price per vial versus multi-vial kits. You can review those differences on the product page and speak with your prescriber about appropriate quantities. Canadian pharmacy fulfillment supports savings for U.S. patients, and orders typically ship using standard methods. Ships from Canada to US with prescription verification and pharmacist review.

Availability and Substitutions

Supply can vary. If your preferred kit is unavailable, your prescriber may recommend a clinically appropriate alternative or adjust quantities. We avoid promising restock dates. If substitution is considered, your pharmacy will confirm that the ingredient, strength, and instructions match the prescription or obtain prescriber approval.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with HIV and problematic visceral adiposity who can self-inject daily and attend regular monitoring. It may not suit people with active cancer, pregnancy, significant pituitary issues, or uncontrolled diabetes. If you have injection anxiety, ask your care team for technique coaching.

Consider multi-month fills when appropriate to reduce per-shipment fees and time. Set calendar reminders for reorders so you do not run out. If your prescriber changes your plan, update your pharmacy promptly. You can browse related peptide options in our Peptides category and review general weight topics in Overweight, keeping in mind that this medicine is not indicated for routine slimming.

Questions to Ask Your Clinician

• Eligibility criteria: Am I a candidate based on my HIV history and current metrics?
• Monitoring plan: How often will you check IGF-1 and glucose?
• Technique: Can you review mixing and subcutaneous injection steps with me?
• Site rotation: Which abdominal areas are best to minimize skin reactions?
• Interactions: Do my current medicines affect this therapy’s safety?
• Goals: What measurements will we use to assess benefit over time?

Authoritative Sources

Review official labeling and safety information:

• FDA Prescribing Information
• Health Canada Drug Product Database
• Manufacturer Information

Ready to proceed? You can buy tesamorelin online with prescription verification and prompt, express shipping with US delivery from Canada. This information is educational and not a substitute for professional medical advice; always follow your prescriber and the official label.