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Tivicay® Tablets for HIV
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Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
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Price range: $234.99 through $688.00
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What Tivicay Is and How It Works
Tivicay® contains dolutegravir, an integrase strand transfer inhibitor for the treatment of HIV-1 infection. It blocks the viral integrase enzyme, which the virus needs to insert its genetic material into human cells. This page helps you understand standard use, safety, and how you can arrange access with clear steps.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
US shipping from Canada is available so you can coordinate refills while traveling or relocating. If you are comparing options, some patients look for Dolutegravir without insurance to understand cash-pay choices alongside plan benefits. For background on therapy classes and testing, see our guides on HIV and Types Of HIV Tests.
Who It’s For
This medicine is used in adults and certain adolescents with HIV-1, as part of a complete antiretroviral regimen. It may be started in people who are new to treatment or those switching from another regimen when appropriate. Individuals with known resistance to integrase inhibitors need individualized plans. People taking dofetilide must not use this treatment due to a serious interaction. Those with significant liver problems, or who are pregnant or planning pregnancy, should review risks and options with a clinician.
Dosage and Usage
Typical schedules involve once-daily dosing with or without food. Some situations call for twice-daily use, such as when certain enzyme-inducing medicines are coadministered or when integrase resistance is present. Follow your prescriber’s instructions and the official label for your exact plan. If antacids or mineral supplements are part of your routine, separate their timing from dolutegravir to support absorption. Patients and caregivers sometimes reference Dolutegravir 50 mg tablets in discussions of standard daily therapy; your clinician will confirm the right tablet and schedule.
Take it at the same time each day. If your regimen includes additional antiretrovirals, use the full combination as prescribed. Do not change doses on your own. For general education about modern regimens, you can also review our overview of INSTI- and NNRTI-based options in the Antivirals category and our article Biktarvy Guide.
Strengths and Forms
Film-coated tablets are the most common presentation. Generic Dolutegravir 50 mg is widely referenced in prescribing resources. Lower-dose tablets and pediatric-friendly dispersible options exist in some markets. Availability may vary by country and by pharmacy partner. Your prescriber will select a strength and form that aligns with your full regimen and any co-prescribed medicines.
Missed Dose and Timing
If you miss a dose and remember soon, take it the same day. If it is close to the next scheduled time, skip the missed dose and return to your routine schedule. Do not double up. Consistency matters for viral suppression, so set reminders or use a pill organizer. If vomiting occurs shortly after a dose, consult the patient information leaflet or ask a clinician how to proceed.
Storage and Travel Basics
Store tablets at room temperature in the original, tightly closed container. Keep the desiccant in the bottle to protect from moisture. Avoid excessive heat or humidity, and keep out of reach of children and pets. When traveling, pack your supply in carry-on luggage with the original labeled container. Bring a copy of your prescription and a medication list. For more travel and testing context, see National HIV Testing Day. A micro-cue for safety: checkout is encrypted to protect your information.
Benefits
This integrase inhibitor can help reduce viral load when used with a fully active regimen. Many patients appreciate once-daily use for routine adherence. The treatment can be taken with or without food, offering flexibility around meals. It has a lower risk of certain interactions compared with older regimens, though some key interactions remain. Consistent use may support improvement in immune markers over time, guided by lab monitoring.
Side Effects and Safety
- Common effects: headache, trouble sleeping, nausea, diarrhea, and fatigue
- Sometimes reported: weight change, dizziness, or mild rash
Serious reactions can occur, including hypersensitivity with rash and organ symptoms, liver problems, and mood changes. Stop the medicine and seek urgent care for signs of severe rash, swelling, shortness of breath, dark urine, yellowing of skin or eyes, or severe abdominal pain. This therapy can interact with other antiretrovirals and non-HIV medicines. Report all supplements and over-the-counter products to your clinician. For additional background, see Aptivus For HIV.
Drug Interactions and Cautions
Dofetilide is contraindicated. Strong enzyme inducers, such as certain anticonvulsants or rifamycins, may lower drug levels; schedules may differ in those settings, per labeling. Cation-containing antacids and minerals can reduce absorption when taken together; separate their timing. Metformin levels may increase; your prescriber may monitor and adjust other therapies if needed. Use caution with St. John’s wort and some polyvalent cation products. Always consult the official label and your clinician for personalized guidance.
What to Expect Over Time
Viral load and CD4 count are monitored routinely. Many people see gradual improvements when adherence is strong and the overall regimen is fully active. Tolerability is often stable after the first few weeks. Your clinician will assess labs for kidney and liver health and watch for interactions after medication changes. If life changes affect routine, consider alarms, blister packs, or synchronized refills to support consistency.
Compare With Alternatives
Within integrase-based care, single-tablet combinations such as Triumeq are commonly discussed when compatible with your history and lab profile. An NNRTI option, Pifeltro, may be considered as part of a different class strategy in selected patients. For broader insights on modern regimens and testing, explore Metformin And HIV as a research perspective and the HIV condition hub.
Pricing and Access
We show transparent options for Dolutegravir Canadian pricing so you can compare cash-pay with plan coverage. You can upload your prescription, see current availability, and choose the supply that fits your routine. US delivery from Canada supports continuity if you are away from home. If you are looking for coupons, see our Promotions page for current notices and tips. Country of origin details appear on product listings; see Canada for more context.
Availability and Substitutions
Stock can vary. If a specific tablet or count is unavailable, your prescriber may recommend a therapeutically appropriate alternative or adjust quantities to maintain your regimen. Pharmacists will confirm substitutions only with clinician approval. If you are exploring options beyond this class, see the Antivirals category and our overview on Biktarvy Guide for educational context.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults and eligible adolescents beginning or maintaining HIV-1 treatment. It is not used for HIV prevention. People with prior integrase inhibitor resistance, severe hepatic impairment, or those on interacting medicines need individualized plans. To save on out-of-pocket costs, consider longer fills when appropriate, ask your clinician about generics, and set up refill reminders so you do not miss doses. Some patients compare cash-pay against insurance to decide how to proceed; others prefer to Buy Dolutegravir online after their prescriber confirms the regimen.
Questions to Ask Your Clinician
- Regimen fit: How does this integrase inhibitor align with my resistance profile?
- Co-medications: Do my supplements or antacids affect timing or absorption?
- Monitoring plan: Which labs will you check and how often?
- Side effects: What symptoms should prompt a call or urgent visit?
- Family planning: What are the considerations if I am pregnant or plan pregnancy?
- Adherence tools: Which reminders or packaging options could help my routine?
Authoritative Sources
Health Canada Drug Product Database
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How does dolutegravir work against HIV?
Dolutegravir inhibits the HIV integrase enzyme. By blocking integrase, the virus cannot insert its genetic material into human DNA, which prevents new infected cells from forming. It is used with other antiretrovirals as a complete regimen. Many people take it once daily, though schedules can differ with certain drug interactions or resistance. Your clinician will confirm the combination and monitor viral load and CD4 counts to track response over time.
Can I take this medicine with antacids or minerals?
Antacids and supplements that contain aluminum, magnesium, calcium, iron, or zinc can bind dolutegravir and reduce absorption. To help avoid this, separate their timing from your dose based on the patient information leaflet or your clinician’s advice. Some regimens allow taking the tablets with food alongside certain supplements, but others require spacing them apart. Always check your instructions, especially when you start or stop over-the-counter products.
What serious side effects should I watch for?
Seek urgent care for signs of a severe allergic reaction, such as rash with fever, swollen glands, mouth sores, or trouble breathing. Also watch for yellowing of skin or eyes, dark urine, severe stomach pain, unusual fatigue, or mood changes. These could indicate liver problems or hypersensitivity. Most people experience only mild effects like headache or nausea, but serious reactions can occur. Keep your care team informed and report new symptoms promptly.
Is dolutegravir safe during pregnancy or breastfeeding?
Guidance continues to evolve. Some data support use during pregnancy when benefits outweigh risks, but decisions are individualized. Share plans for pregnancy and breastfeeding with your clinician before starting therapy. They will consider alternatives, timing of conception, and your viral load. Breastfeeding guidance differs by country and clinical context. Follow your local recommendations and your prescriber’s advice to reduce transmission risks and support infant safety.
What if I miss a dose?
If you miss a dose and remember later the same day, take it. If it is close to the next dose, skip the missed dose and continue your schedule. Do not take two doses at once. Consistency supports viral suppression, so consider alarms, smartphone reminders, or pill organizers. If you vomit soon after a dose, check the patient leaflet or contact your healthcare professional for next steps based on timing.
Are there important drug interactions?
Yes. Dofetilide must not be used with dolutegravir. Strong enzyme inducers such as certain anticonvulsants or rifamycins can lower levels, and schedules may differ in those cases. Cation-containing antacids and mineral supplements reduce absorption if taken together; separate dosing as instructed. Metformin levels may rise and require monitoring. Keep an updated medication list and share it with your prescriber and pharmacist at every visit.
How should I store my tablets at home and during travel?
Keep tablets in the original, tightly closed bottle at room temperature, away from excess heat and moisture. Do not remove the desiccant. For travel, carry your supply in hand luggage with the labeled container and a copy of your prescription. Pack extra doses if trips may be prolonged, and avoid leaving medicine in a hot car. Store out of reach of children and pets, and follow local rules for safe storage and transport.
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