Trulance

Uses of Trulance

Trulance is used to treat chronic idiopathic constipation or irritable bowel syndrome with constipation.

Trulance works by activating certain substances within your intestines that help increase fluid secretion and muscle movement.

Trulance also causes changes in the consistency of your stools.

Precautions and Warnings

You should not use Trulance if you are allergic to plecanatide, or if you have a blockage in your intestines.

Adults who cannot swallow Trulance tablets whole may crush the tablet and mix with applesauce or dissolve the tablet in water before swallowing. Trulance tablets may also be taken with water by adults through a nasogastric or gastric feeding tube.

You should not use Trulance if you are allergic to plecanatide , or if you have:

• a blockage in your intestines.

Do not give this medicine to a child younger than 6 years old.

Avoid using Trulance in anyone younger than 18 years old. In animal studies, plecanatide caused severe dehydration leading to death.

Tell your doctor if you are pregnant or breastfeeding.

Dosage

Usual Adult Dose for Chronic Idiopathic Constipation: 3 mg orally once a day

Side Effects

Common side effects:

• Abdominal bloating or tenderness
• dizziness
• infections, such as the common cold or urinary tract infection
• nausea
• mild diarrhea