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Viraday 600 mg/200 mg/300 mg Tablets
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Viraday is a single-tablet antiretroviral medicine that combines efavirenz, emtricitabine, and tenofovir disoproxil fumarate for HIV-1 treatment. Ships from Canada to US for people using cash-pay options, including those without insurance. This page explains what the combination does, how it’s commonly used, and what safety topics to review with a healthcare professional.
Medication choices for HIV can feel complicated, especially when switching regimens or managing side effects. The sections below summarize practical, label-aligned basics and point to related hubs and guides, including the HIV Care Overview, for broader context.
What Viraday Is and How It Works
This medicine is a fixed-dose combination tablet that contains three antiretroviral drugs (HIV medicines) in one pill. Efavirenz is an NNRTI (non-nucleoside reverse transcriptase inhibitor), while emtricitabine and tenofovir disoproxil fumarate are NRTIs (nucleoside reverse transcriptase inhibitors). Each ingredient targets HIV replication in a different way, which helps suppress the virus when taken as prescribed.
Dispensing is arranged through licensed Canadian partner pharmacies. Availability and documentation requirements can vary by region and prescription status, so it helps to review ordering steps before starting. For browsing related therapies by class, see the Antiviral Medicines category hub. US delivery from Canada may also affect how refills are planned, especially around holidays or travel.
Who It’s For
Viraday is used as part of HIV-1 treatment in people when a prescriber determines this specific three-drug combination is appropriate. It is not intended for HIV prevention, and it is not a cure. Some people may need a different regimen based on prior treatment history, drug resistance results, liver or kidney health, pregnancy considerations, or co-infections such as hepatitis B.
This option may not be suitable for everyone. Key reasons a clinician may avoid or reconsider this regimen include a history of severe rash with similar medicines, significant psychiatric symptoms that could worsen with efavirenz, or important drug interactions that cannot be managed. For plain-language background on terminology and diagnosis, the articles HIV Vs AIDS Differences and Types Of HIV Tests can be helpful starting points.
Dosage and Usage
Viraday is typically taken once daily as directed on the prescription label. Because this product combines three active ingredients, it should not be taken together with other medicines that duplicate emtricitabine or tenofovir disoproxil fumarate unless a prescriber has a specific plan. If a dose is missed, the safest next step is to follow the written instructions provided by the pharmacy or prescriber rather than guessing or doubling up.
Some product labeling for efavirenz-containing combinations describes taking the dose on an empty stomach and often at bedtime, because certain nervous system effects (like dizziness or vivid dreams) can be more noticeable. Individual instructions can differ, especially when other conditions or medicines are involved. For ingredient-level context on tenofovir/emtricitabine products, see the Tenvir EM Guide.
Quick tip: Keep an up-to-date medication list in your account to reduce refill confusion.
Strengths and Forms
Viraday is supplied as an oral tablet that contains efavirenz 600 mg, emtricitabine 200 mg, and tenofovir disoproxil fumarate 300 mg in a single fixed-dose unit. This “all-in-one” approach is meant to simplify dosing schedules compared with taking separate pills. Packaging formats and tablet appearance can vary by manufacturer and market, even when the active ingredients and strengths match.
Availability may also vary over time depending on supply conditions and regulatory pathways. If a prescriber is considering a switch, they usually review prior regimen history, HIV RNA (viral load) trends, resistance testing when available, and tolerability. When comparing options, it can help to focus on the drug classes involved, potential interactions, and monitoring needs rather than pill count alone.
Storage and Travel Basics
Store this medicine at controlled room temperature, away from excess heat and moisture. Keep tablets in the original container or packaging when possible, and close the lid tightly after each use. Bathrooms and vehicles can be poor storage choices because humidity and temperature swings may affect tablet quality over time. Keep all prescription medicines out of reach of children and pets.
For travel, planning matters because missed doses can reduce treatment consistency. Carry enough medicine for the full trip plus a small buffer, and keep it in hand luggage to avoid loss in checked bags. If documentation is needed at borders, a pharmacy label and a copy of the prescription are commonly used references.
Quick tip: Save a photo of the label and prescriber details for travel paperwork.
Side Effects and Safety
Viraday can cause side effects, and many are related to efavirenz. Commonly discussed effects include dizziness, sleep changes, vivid dreams, fatigue, nausea, diarrhea, and rash. These can be mild for some people and more disruptive for others, especially during early weeks of therapy. A clinician may review timing of doses, food effects, and mental health history to reduce avoidable risk.
More serious safety concerns may include severe skin reactions, mood changes (including depression or suicidal thoughts), liver inflammation, and rare lactic acidosis (a dangerous buildup of lactic acid). Tenofovir disoproxil fumarate can also affect kidney function and bone health in some people, so labs and clinical monitoring are often part of routine follow-up. Rash can have many causes in HIV, and guidance on symptom patterns is discussed in Skin Symptoms In HIV. People with kidney risk factors may find added context in Kidney Disease And HIV.
Why it matters: Stopping certain HIV medicines abruptly can be risky, especially with hepatitis B co-infection.
Drug Interactions and Cautions
Efavirenz can change how the liver processes many medicines, which may raise or lower drug levels. Prescriptions are confirmed with the prescriber before dispensing. Sharing a complete medication list helps reduce interaction surprises, including over-the-counter products and supplements. St. John’s wort is a common example of an herbal product that can interfere with antiretroviral therapy.
Important interaction categories to review with a clinician or pharmacist include:
- Seizure medicines and sedatives
- Antifungals and antibiotics
- Rifampin-like tuberculosis drugs
- Hormonal contraceptives
- Blood thinners and heart drugs
- Other HIV antivirals
Because emtricitabine and tenofovir disoproxil fumarate are also used in other combinations, duplication can occur if multiple HIV products are taken together. Pregnancy planning and liver disease are additional caution areas that typically require individualized clinical review.
Compare With Alternatives
Viraday is one of several ways clinicians may combine drug classes to control HIV. Alternatives differ by active ingredients, side-effect patterns, resistance barriers, and interaction profiles. For example, some regimens use integrase inhibitors rather than efavirenz, while others separate the “backbone” drugs from the third agent. Broader context on how treatment choices have changed over time is discussed in HIV Treatment Landscape.
The comparisons below are high level and not a recommendation:
| Option | What it is | Key considerations |
|---|---|---|
| Truvada Details | Two-drug NRTI backbone | Needs a third agent for full HIV treatment |
| Stribild Details | Single-tablet integrase-based combination | Includes a booster (cobicistat), affecting interactions |
| Combivir | Older two-drug NRTI combination | Often used in specific scenarios, not first-line broadly |
A prescriber typically considers prior therapy, resistance testing, kidney and liver status, and tolerability when selecting among options.
Pricing and Access
Viraday pricing can vary based on supply channel, strength presentation, and pharmacy dispensing requirements. Some people compare the overall regimen expense rather than focusing only on one product’s cost per tablet, since lab monitoring and companion medicines may also matter. When a prescription is on file, access is generally handled as a cash-pay transaction, which can be relevant for those managing coverage gaps.
Cash-pay access can help when insurance isn’t available. BorderFreeHealth supports US shipping from Canada through its partner-pharmacy model after prescription verification. If coverage changes occur, a clinician may need to recheck whether the same combination remains appropriate, especially if other medicines are added or stopped.
Authoritative Sources
For the most reliable, up-to-date details, confirm information against official labeling and clinical guidelines. These sources can clarify contraindications, interaction tables, monitoring suggestions, and warnings that may not be captured in brief summaries. They are also useful when a prescriber is considering a switch or when new symptoms appear after starting therapy.
Use the links below as neutral references, and bring questions to a qualified healthcare professional who can interpret them for an individual medical history.
U.S. prescribing details for the fixed-dose combination are in DailyMed Atripla Label.
National guidance on antiretroviral therapy appears in NIH HIV Clinical Guidelines.
For site actions, submit prescription details through your account and select prompt, express shipping when available.
This content is for informational purposes only and is not a substitute for professional medical advice.
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What is Viraday used for?
Viraday is a fixed-dose combination antiretroviral medicine used for the treatment of HIV-1 infection when a prescriber determines the three-drug combination is appropriate. It contains efavirenz plus two nucleoside/nucleotide reverse transcriptase inhibitors (emtricitabine and tenofovir disoproxil fumarate). The goal of therapy is to suppress HIV replication as part of an ongoing treatment plan. It is not a cure, and it is not intended for HIV prevention. Suitability depends on factors like prior treatment history, resistance testing, other conditions, and potential drug interactions.
How is the efavirenz/emtricitabine/tenofovir tablet usually taken?
This combination tablet is commonly prescribed as one dose taken once daily, following the directions on the prescription label. Because it includes efavirenz, some prescribing information describes taking it on an empty stomach and often at bedtime, since nervous system effects (such as dizziness or vivid dreams) may be more noticeable with food or during daytime activities. Directions can differ based on other medicines and health conditions. If a dose is missed, written pharmacy instructions or prescriber guidance should be followed rather than doubling doses.
What are common side effects of this combination?
Side effects can include dizziness, sleep disturbance, vivid dreams, fatigue, nausea, diarrhea, headache, and rash. Many effects are associated with efavirenz, especially early in treatment. Some people also notice mood changes or difficulty concentrating. Not everyone experiences these effects, and severity varies. Because symptoms like rash or abdominal discomfort can have multiple causes, it is important that any new or worsening symptoms are evaluated by a clinician who can assess timing, other medications, and possible alternative explanations.
What serious reactions or monitoring issues should I know about?
Serious risks described for efavirenz/emtricitabine/tenofovir disoproxil fumarate regimens can include severe skin reactions, significant mood or behavioral changes (including suicidal thoughts), liver inflammation, and rare lactic acidosis. Tenofovir disoproxil fumarate may also affect kidney function and can contribute to bone mineral density loss in some people. Monitoring often includes kidney and liver labs and routine HIV markers (viral load and CD4 count). People with hepatitis B may need added caution if therapy is stopped or changed.
Which drug interactions matter most with efavirenz-based regimens?
Efavirenz can alter the metabolism of many medicines by affecting liver enzymes, which may raise or lower levels of other drugs. Important interaction categories include certain seizure medicines, sedatives, some antifungals, rifampin-like tuberculosis drugs, blood thinners, and other antivirals. Hormonal contraceptives may be less effective with enzyme-inducing medicines, so clinicians may recommend additional precautions. Over-the-counter products and supplements also matter; St. John’s wort is a well-known example that can interfere with antiretroviral therapy.
What should I ask my clinician before starting or switching to this tablet?
Helpful questions include whether this combination fits prior HIV treatment history and any available resistance testing, and how it may affect mental health symptoms or sleep. It’s also reasonable to ask what baseline labs are needed (kidney function, liver enzymes, hepatitis B status) and how often follow-up testing is expected. Bring a complete list of prescription drugs, over-the-counter products, and supplements to review interactions. If pregnancy is possible, ask how efavirenz-containing regimens are handled in pregnancy planning and what alternatives exist if needed.
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