Vyzulta® Ophthalmic Solution for Open-Angle Glaucoma

This prescription eye drop lowers pressure inside the eye in adults. Vyzulta® is used for open-angle glaucoma and ocular hypertension. You can access Canadian pricing with US delivery from Canada, which may help if paying without insurance.

What Vyzulta Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Vyzulta® contains latanoprostene bunod, a prostaglandin analog that donates nitric oxide. After instillation, it converts to latanoprost acid and a nitric oxide donor. This dual action increases aqueous humor outflow through both the trabecular meshwork and the uveoscleral pathway. By improving these routes, it lowers intraocular pressure. As a result, the treatment helps reduce the risk of optic nerve damage over time. The class is commonly used as first-line therapy for many adults with chronic pressure elevation.

Latanoprostene bunod 0.024% ophthalmic solution is designed for once-daily dosing. It includes benzalkonium chloride as a preservative. Contact lenses should be removed before using the drop and reinserted after a short wait. For condition education and product context, explore our Ophthalmology category.

Who It’s For

This medicine is indicated to reduce intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Some adults who have not reached target pressure on other therapies may also use this treatment as directed by their prescriber. Vyzulta for glaucoma is often considered when once-daily dosing is preferred.

People with a history of herpetic keratitis, active intraocular inflammation, or risk factors for macular edema should discuss suitability with a clinician. Those who are aphakic or pseudophakic with a torn posterior lens capsule may require extra caution. If you have specific questions about these conditions, see our pages on Open Angle Glaucoma and Ocular Hypertension.

Dosage and Usage

Use one drop in the affected eye or eyes once daily in the evening, as described in the official label. Do not use more than once per day, since higher frequency may lessen the pressure-lowering effect. Wash hands before handling the bottle. Tilt your head back, gently pull down the lower eyelid to create a small pocket, and instill one drop without touching the eye or lashes.

After the drop lands, close your eye and press lightly at the inner corner for one to three minutes. This can help limit systemic absorption. If you use other topical eye medicines, separate administrations by at least five minutes. Remove soft contact lenses before dosing and wait at least 15 minutes before reinserting them.

Always follow your prescriber’s directions and the patient information leaflet. Do not share the bottle with others.

Strengths and Forms

This treatment is supplied as a sterile, preserved solution in a dropper bottle for ophthalmic use. The following presentation is commonly available; availability may vary by pharmacy and time.

• Latanoprostene bunod 2.5 mL 0.024%

Packaging, excipients, and labeling depend on the manufacturer and market. Your exact bottle and carton may differ from images online.

Missed Dose and Timing

If you miss the nightly drop, administer the next dose at the usual time the following evening. Do not double up or catch up with an extra drop. Keep a consistent schedule to support stable pressure control.

Storage and Travel Basics

Store the bottle at room temperature away from excessive heat, moisture, and direct light. Keep the cap tightly closed and the dropper tip clean. Do not touch the tip to any surface, including the eye or fingers. Keep out of reach of children and pets.

For travel, keep the medicine in its original packaging with the prescription label. Pack it in your carry-on bag to avoid extreme temperatures in checked baggage. If crossing borders, bring a copy of your prescription or a photo of the label. When flying, avoid placing the bottle near windows or vents. If you use contact lenses, carry a lens case and saline so you can remove lenses before dosing.

Benefits

This therapy is once daily and fits many evening routines. Nitric oxide donation may help enhance outflow through the trabecular meshwork, complementing the uveoscleral effect typical of the prostaglandin class. Many patients appreciate that a single daily drop can simplify adherence compared with multi-dose regimens. Consistent use can support sustained pressure reduction when directed by a prescriber.

Side Effects and Safety

• Eye redness
• Mild burning or stinging
• Eye irritation or discomfort
• Blurred vision after instillation
• Eyelash growth or darkening
• Iris or eyelid skin pigmentation changes

Serious but less common risks include macular edema, intraocular inflammation, or reactivation of herpetic keratitis. Periorbital fat changes and increased iris pigmentation may be permanent. Stop use and seek medical care for severe eye pain, vision changes, light sensitivity, or signs of infection. Remove contact lenses before dosing, since preservatives such as benzalkonium chloride can be absorbed by soft lenses. If you are pregnant, breastfeeding, or planning eye surgery, discuss use with your healthcare professional.

Drug Interactions and Cautions

Using more than one prostaglandin analog may reduce effectiveness or raise the risk of side effects. If multiple topical ophthalmic medicines are prescribed, separate them by at least five minutes, and use gels or ointments last. Tell your clinician about all eye products and systemic medicines you take. People with a history of uveitis, cystoid macular edema, or herpes simplex keratitis should use caution. If you wear soft contact lenses, remove them before use and wait before reinsertion.

What to Expect Over Time

Some people notice mild eye redness or transient blur right after a dose. Pressure reduction is expected with daily, consistent use. Your prescriber may check pressure at follow-up visits and adjust therapy if needed. Keep the dosing time steady, track each bottle’s opening date, and set reminders to support adherence. If irritation persists or gets worse, contact a clinician for guidance.

Compare With Alternatives

Several approved prostaglandin options exist. Travoprost is available as Travatan Z, which uses a different preservative system. Latanoprost is another benchmark option, sometimes preferred by prescribers as initial therapy. This medicine’s nitric oxide donation is a key mechanistic distinction versus many single-pathway agents. For a broader overview of topical combinations sometimes used in glaucoma care, you can read What Are The Alternatives To Combigan.

Pricing and Access

We list current options so you can review Vyzulta eye drops price and compare formats. For many customers, Vyzulta price without insurance is lower under Canadian sourcing. Ordering includes transparent pricing and clear refill paths. We provide encrypted checkout, and prescriptions are verified with your prescriber before dispensing.

Our marketplace reflects Canadian pricing with fulfillment that Ships from Canada to US. If you are exploring country-of-origin details, see Canada. Looking for deals or seasonal offers? See our Promotions page for current opportunities.

Availability and Substitutions

Supply can vary by manufacturer and pharmacy. If this item is temporarily unavailable, a prescriber may recommend a suitable alternative from the same class. Order latanoprostene bunod online only with a valid prescription, and use it exactly as directed by your clinician.

Patient Suitability and Cost-Saving Tips

This therapy may be appropriate for adults who need consistent pressure reduction with once-daily dosing. It may not suit those with a history of uveitis, macular edema, or herpetic keratitis unless a prescriber advises otherwise. If you have sensitivity to preservatives, talk with your clinician about options and lens care. Report any vision changes promptly.

To manage costs, consider multi-month fills when appropriate to reduce per-bottle fees and fewer transactions. Set reminders to reorder before your bottle runs low. Store your bottle correctly to avoid waste from contamination. Keep your follow-up appointments; consistent monitoring helps avoid unnecessary therapy changes that can increase costs.

Questions to Ask Your Clinician

• Is this drop suitable for my type of glaucoma?
• What pressure target are we aiming for with this treatment?
• How should I time this drop with my other eye medicines?
• What side effects should prompt me to call your office?
• Could contact lens wear affect tolerability or use?
• If redness persists, what alternatives should we consider?

Authoritative Sources

Manufacturer: Bausch + Lomb VyzultaFDA DailyMed LabelHealth Canada Drug Product Database

Start your order for US shipping from Canada with prompt, express shipping. This page is informational and not a substitute for professional medical advice; always follow your prescriber and the official label.