Xalkori

Xalkori is a cancer medicine used to treat certain types of non-small cell lung cancer (NSCLC) that have changes in the ALK or ROS1 genes. These gene changes help cancer grow, and Xalkori works by blocking them. It helps slow down or stop cancer from spreading.

Benefits

• Targets the specific gene changes (ALK or ROS1) that drive some lung cancers.
• Can shrink tumors and slow down the growth of cancer.
• Taken as a pill, so treatment can happen at home.
• Works well in many patients, even when other treatments haven’t.
• May help people live longer and feel better.

Dosage

• Usually taken as 250 mg twice a day — one pill in the morning and one at night.
• Take it the same time every day, with or without food.
• Swallow the capsule whole — don’t chew or crush it.
• Your doctor may adjust the dose based on how you respond or any side effects.

Warnings and Precautions

• Can affect your vision — things might look blurry or lights may seem brighter.
• May slow your heart rate — tell your doctor if you feel dizzy or faint.
• Can impact your liver — regular blood tests are important.
• Tell your doctor if you have heart, liver, or kidney problems.
• Not safe in pregnancy or breastfeeding — use birth control while on treatment.

Usage Instructions

• Take exactly as prescribed — don’t miss doses or stop on your own.
• If you miss a dose and it’s been less than 6 hours, take it. If it’s been longer, skip it.
• Don’t take extra to make up for a missed dose.
• Keep all follow-up appointments and blood tests to monitor your health.

Storage Information

• Store at room temperature, away from heat, light, and moisture.
• Keep the bottle tightly closed.
• Keep out of reach of children.

Common Side Effects

• Mild to moderate effects: vision problems (blurry vision, seeing flashes), nausea, diarrhea, tiredness, swelling in hands or feet, and changes in taste.
• Serious (seek medical help): chest pain, slow heartbeat, liver problems (yellow skin or dark urine), or breathing difficulties like shortness of breath or cough that doesn’t go away.