Xtandi® Tablets for Prostate Cancer

Enzalutamide is an oral androgen receptor inhibitor used for prostate cancer. This page explains what it treats, how to use it safely, and how to access it with US shipping from Canada. We also outline options for Enzalutamide without insurance.

What Xtandi Is and How It Works

Xtandi® contains enzalutamide, a medicine that blocks androgen receptor signaling. By reducing the effect of androgens on tumor cells, it helps slow disease progression in certain stages of prostate cancer. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

It is used in adults for metastatic castration-resistant prostate cancer and metastatic castration-sensitive disease, and in some settings of non-metastatic castration-resistant disease per approved labeling. The treatment is taken by mouth and does not require routine clinic administration. Always review the official patient information and follow your prescriber’s instructions.

Who It’s For

This therapy is prescribed for adults with prostate cancer, including castration-resistant and metastatic castration-sensitive indications. Many people continue medical or surgical androgen deprivation during treatment. See our overview of the condition here: Prostate Cancer.

Those with a history of seizures, significant uncontrolled hypertension, severe liver issues, or prior hypersensitivity to components may not be suitable. Discuss risks if there is a history of falls, fractures, or cardiovascular disease. Women who are or may become pregnant should avoid handling broken tablets.

Dosage and Usage

The standard regimen is a total daily dose of 160 mg, taken once a day at about the same time. Swallow tablets whole with water, with or without food. Do not crush, chew, or split. Continue androgen deprivation therapy if not surgically castrated, unless your prescriber defines a different plan.

Take it consistently. If you experience concerning effects, contact a healthcare professional promptly. Do not change your dose on your own. For complete directions, rely on the current FDA or Health Canada labeling and your prescriber’s guidance.

Strengths and Forms

Common presentations include Enzalutamide 40 mg tablets and 80 mg tablets. Availability can vary by market and manufacturer packaging. Your prescription will specify the strength and total tablets per fill. If the strength you were prescribed is not available, your prescriber may adjust the number of tablets to reach the same total daily dose.

Missed Dose and Timing

If you miss a dose, take the next dose at your usual time the following day. Do not take two doses at once to make up for a missed dose. If you vomit after taking a dose, do not take an extra tablet; wait until your next scheduled dose. Try to keep a daily routine to help avoid missed doses.

Storage and Travel Basics

Store tablets at room temperature in the original container, protected from excess heat and moisture. Keep out of reach of children and pets. Caregivers should handle intact tablets with dry hands and wash afterwards; avoid contact with broken tablets. When you travel, keep your medicine in carry-on baggage with the label and your prescription details. For cross-border trips, a copy of your prescription and a medication list can help with screening. Our partner pharmacies use temperature-controlled handling when required.

Benefits

This treatment targets the androgen receptor pathway that drives growth in many prostate tumors. Oral dosing offers convenience compared with some clinic-administered options. In appropriate indications, it may delay disease progression and help manage symptoms. Many patients value the once-daily schedule and the ability to take it with or without food, which can simplify routines.

Side Effects and Safety

• Common: fatigue, hot flushes, joint or back pain, headache, dizziness
• Blood pressure: increases can occur; monitoring is often recommended
• Gastrointestinal: decreased appetite, diarrhea, constipation, nausea
• Swelling: peripheral edema can occur
• Falls and fractures: risk may be higher in some patients

Serious but less common risks include seizures, posterior reversible encephalopathy syndrome, allergic reactions, and cardiovascular events. If you develop severe headache, confusion, fainting, chest pain, shortness of breath, or a seizure, seek urgent medical care. Your care team may monitor blood pressure and other labs during therapy.

Drug Interactions and Cautions

Enzalutamide can affect how other medicines work. It is known to induce CYP3A4 and can influence CYP2C9 and CYP2C19, which may lower levels of sensitive substrates such as warfarin and certain antiepileptics, immunosuppressants, and antidepressants. Strong CYP2C8 inhibitors or inducers can change enzalutamide exposure. Provide your full medication list, including over-the-counter products and supplements, to your prescriber and pharmacist.

Because of seizure risk, use caution with activities where sudden loss of consciousness would be dangerous. Alcohol and sleep agents may add to sedation or dizziness. Your prescriber may recommend bone health measures if you have fracture risk.

What to Expect Over Time

This medicine is often used long term until disease progression or unacceptable side effects. Your care team may follow PSA, imaging, symptoms, and blood pressure over time to assess response and tolerability. It is reasonable to expect day-to-day variability in energy levels. Building a consistent medication routine, staying hydrated, and reporting new or worsening symptoms promptly can support safe ongoing use.

Some people need additional therapies over the course of treatment, including bone-supporting agents or changes in hormonal therapy. Review educational resources on maintaining health during treatment, such as Prostate Health and Cancer Screenings For Seniors.

Compare With Alternatives

Other approved options for advanced prostate cancer include abiraterone plus prednisone and other androgen pathway inhibitors. Two alternatives we stock are Zytiga and Nubeqa. Choice of therapy depends on cancer stage, prior treatments, comorbidities, potential interactions, and prescriber preference. Your oncology team will advise which option aligns with your treatment plan.

Pricing and Access

We highlight options to reduce the Xtandi price without insurance and outline ways to Buy enzalutamide with transparent Canadian pharmacy pricing. Many patients see meaningful differences between Canadian and U.S. cash-pay amounts. This product Ships from Canada to US after your prescription is validated. For category context, explore our Cancer medications and country-of-origin details here: Canada.

To review current options and any limited-time offers, see Promotions. If you are new to our site, you can place an order online once your prescriber sends a valid prescription. Payment is handled through secure checkout. For condition background, we also provide an overview on Prostate Cancer.

Availability and Substitutions

Supply can vary. If a specific strength or packaging is temporarily unavailable, a prescriber may suggest an alternative strength or a different approved agent. We cannot guarantee restock dates. Your care team decides whether a substitution is appropriate for your regimen.

Patient Suitability and Cost-Saving Tips

Adults with advanced prostate cancer may be candidates if the prescriber determines the benefit outweighs risks given comorbidities and concomitant medicines. People with seizure history or uncontrolled hypertension may need closer monitoring or a different option. For budgets, consider multi-month fills when appropriate to lower per-fill fees, and set refill reminders so you do not run out while traveling.

Discuss the Enzalutamide price with your care team so they can consider support programs or alternative therapies if needed. You can use our site tools to compare cash-pay options and manage refills. Keep receipts and prescription copies handy for travel or reimbursement paperwork.

Questions to Ask Your Clinician

• Appropriate goal: how this therapy fits my overall cancer plan
• Duration: what would lead us to stop or change treatment
• Monitoring: which labs or checks are needed and how often
• Interactions: which medicines or supplements to avoid
• Safety: seizure, blood pressure, fall, and bone-health precautions
• Lifestyle: activity and hydration guidance during therapy

Authoritative Sources

FDA DailyMed

Health Canada Drug Product Database

Astellas Pharma US

Ready to proceed? Order Xtandi online today with prompt, express shipping and reliable US delivery from Canada. This page is informational and does not replace medical advice; your prescriber determines your treatment.