Zytiga® Tablets for Prostate Cancer

Zytiga is an oral androgen biosynthesis inhibitor for advanced prostate cancer. This page explains key uses, safety basics, and how to access treatment with US delivery from Canada. You can also review typical costs without insurance.

What Zytiga Is and How It Works

Zytiga® contains abiraterone acetate, which lowers androgen production in the body. It blocks CYP17, a critical enzyme for testosterone synthesis in the testes, adrenal glands, and tumor tissue. Lowering these hormones can slow disease progression in metastatic prostate cancer when used with prednisone. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Abiraterone Acetate tablets are taken on an empty stomach. Food raises exposure, so dosing follows fasting rules to support consistent levels. This medicine is commonly combined with ongoing medical castration using a GnRH analog or after orchiectomy.

Who It’s For

This treatment is indicated for adult men with metastatic castration-resistant prostate cancer and for metastatic castration-sensitive prostate cancer, used with prednisone as directed by the label. It is not intended for use in women or children. People with severe liver impairment, uncontrolled hypertension, low potassium, or heart failure require careful evaluation by a prescriber.

Patients managed for prostate cancer may also review our Prostate Cancer category and broader Cancer options for context on therapy classes and supportive care. For background on men’s health, see Understanding Prostate Health.

Dosage and Usage

Typical labeled dosing is 1,000 mg by mouth once daily on an empty stomach. Take it at least one hour before food or two hours after food. Swallow the tablets whole with water. Do not crush or split tablets. This therapy is used with prednisone; the prescribed prednisone schedule differs by indication. Follow the official label and your prescriber’s directions.

Maintain any concurrent androgen deprivation therapy unless directed otherwise. If vomiting occurs after a dose, do not take an extra tablet; resume at the next scheduled time. For patient education, you may review Abiraterone patient information on official sources linked below.

Clinicians monitor liver function tests regularly, especially early in treatment or after dose adjustments. Blood pressure, potassium, and fluid status are also checked due to mineralocorticoid-related effects.

Strengths and Forms

Film-coated tablets are available as the commonly published 250 mg and 500 mg strengths. Availability may vary by manufacturer and supply. Many patients use one daily dose that equals 1,000 mg, as directed by the label. Your pharmacy may dispense the brand or an authorized equivalent based on your prescription and stock.

Some listings will note Abiraterone 500 mg tablets as a higher-strength option to reduce pill count. Selection may depend on availability and your prescriber’s instructions.

Missed Dose and Timing

If you miss a dose, take your next dose at the usual time the following day. Do not double up to make up for a missed dose. Keep taking prednisone as prescribed. Use a reminder system to support steady, daily use. Consistent timing can help maintain stable exposure.

Storage and Travel Basics

Store tablets at room temperature in the original container. Keep the bottle closed, dry, and away from excess heat and light. Do not store in the bathroom. Keep out of reach of children and pets.

When you travel, carry the medicine in your hand luggage along with a copy of your prescription. Use a timed reminder to avoid missing doses across time zones. If security screening is expected, keep the labeled pharmacy container visible to simplify inspection. Dispose of unused or expired tablets through a community take-back program when possible.

Pen Handling and Sharps Disposal

This product is supplied as oral tablets. Pens, vials, and needles are not used. Sharps containers are not required for this therapy.

Benefits

This treatment reduces androgen production that can fuel tumor growth. It can be used in combination with standard hormonal therapy and prednisone. Oral dosing offers home use convenience. Taking it without food helps keep levels predictable. Many patients value once-daily scheduling with clear monitoring plans.

Side Effects and Safety

• Fluid retention and swelling
• Hypertension
• Low potassium
• Fatigue
• Hot flush
• Joint discomfort
• Upset stomach
• Elevated liver enzymes

Serious risks can include hepatotoxicity, adrenocortical insufficiency, and severe low potassium that may lead to arrhythmias. Adrenal insufficiency can occur with abrupt steroid changes, infection, or stress. Women who are pregnant or may become pregnant should not handle broken tablets. For comprehensive details, see Abiraterone acetate side effects in the official labeling linked below.

Drug Interactions and Cautions

Abiraterone is a CYP3A4 substrate and inhibits CYP2D6 and CYP2C8. Strong CYP3A4 inducers may reduce exposure. Concomitant use with sensitive CYP2D6 substrates or narrow therapeutic index agents may require monitoring. Check all prescription and nonprescription medicines, vitamins, and herbal products with your clinician.

Blood pressure, potassium, and liver tests are checked regularly. Abiraterone monitoring labs often include AST, ALT, bilirubin, and periodic electrolytes. Tell your healthcare professional about any history of liver disease, heart failure, recent cardiovascular events, or adrenal disorders. Follow label guidance for dose modifications in hepatic impairment.

What to Expect Over Time

Response evaluations are typically based on clinical assessment, labs such as PSA, and imaging schedules set by your oncology team. Some people notice changes in energy or fluid status during the first weeks. Regular follow-up supports safe use by tracking blood pressure and liver tests. If your prescriber adjusts your plan, keep using reminder tools, refill early, and update your medication list at each visit. Adherence to the fasting schedule can help keep day-to-day exposure steady.

For broader wellness context, see Health Screenings For Men. Seniors and caregivers may also find Cancer Screenings For Seniors useful when discussing monitoring plans.

Compare With Alternatives

Other approved androgen-receptor pathway options include darolutamide and enzalutamide. Talk with your clinician about tumor stage, prior therapy, comorbidities, and potential interactions when considering alternatives. Two examples available here are Nubeqa and Xtandi. Selection depends on your diagnosis, tolerance, and goals of care.

Pricing and Access

Canadian pharmacy pricing can provide meaningful savings for many patients paying cash. You can review Zytiga price without insurance on the product page and compare with the Generic abiraterone price when available. We provide transparent details so you can discuss options with your prescriber and plan refills on time. For periodic offers, see our Promotions. We also note origin details on relevant product pages, including Canada. Ordering includes clear steps and US shipping from Canada to your address.

Availability and Substitutions

Supply can vary by manufacturer and strength. If an item is temporarily unavailable, your prescriber may recommend a suitable alternative or generic equivalent. We dispense only with a valid prescription. For site security, checkout is encrypted. If you have questions about source or stock, contact support before placing your order.

Patient Suitability and Cost-Saving Tips

Adults with metastatic disease who can follow fasting requirements and monitoring are typical candidates. Those with uncontrolled hypertension, severe hepatic impairment, or a history of significant cardiovascular events need individualized assessment. If using a sulfonylurea or insulin separately for diabetes, note that steroid co-therapy may affect glucose control; your clinician can advise on monitoring.

To save on costs, ask your prescriber about multi-month fills when appropriate. Scheduling shipments ahead of time helps avoid gaps. Set refill reminders on your phone or calendar. If your plan changes, update your order timing to match clinic follow-ups and lab checks. Patients paying cash may compare brand and generic options to balance access and continuity.

Questions to Ask Your Clinician

• Fasting timing: how strictly should I schedule dosing with meals
• Prednisone plan: what dose and duration are right for me
• Monitoring: which labs and how often at the start
• Blood pressure and potassium: how should I track at home
• Liver safety: when would dose holds or changes be considered
• Interactions: are my heart or blood pressure medicines affected
• Travel: how to time doses across time zones

Authoritative Sources

FDA DailyMed: Zytiga Prescribing Information

Manufacturer Label: Janssen Zytiga

Health Canada Drug Product Database: Abiraterone

Ready to get started? You can place your order today with prompt, express shipping and temperature-controlled handling when required. This content is for general information and does not replace the official label or your clinician’s guidance.