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Cimetidine dosage

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Written by BFH Staff Writer on April 14, 2023

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Cimetidine dosage. Cimetidine treats conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It works by reducing the production of stomach acid, which can alleviate symptoms such as heartburn, acid indigestion, and stomach pain.

However, taking the correct dosage of cimetidine is crucial to ensure its effectiveness and minimize the risk of side effects.

Dosage for GERD and Peptic Ulcers

The recommended dosage of cimetidine for GERD and peptic ulcers is typically 800mg per day, divided into two or four doses. The frequency of dosing may depend on the individual’s medical condition and the severity of their symptoms.

For example, some people may take 400mg of cimetidine twice a day, while others may take 200mg of cimetidine four times a day. The dosage may also be adjusted for people with renal impairment to avoid the risk of drug accumulation and toxicity.

Dosage for Other Conditions

 

Dosage for Zollinger-Ellison Syndrome

The recommended dosage for Zollinger-Ellison Syndrome may vary depending on the severity of the condition and the individual’s response to treatment. In general, the dosage may range from 20mg to 160mg of cimetidine per day, divided into two to four doses. The maximum daily dose should not exceed 2.4 grams per day, unless directed by a healthcare provider.

Dosage for Prophylaxis of Stress Ulcers

The recommended dosage for prophylaxis of stress ulcers may depend on the individual’s medical condition and the risk of developing ulcers. In general, the dosage may range from 200mg to 400mg of cimetidine every 6 to 8 hours.

Dosage for Systemic Mastocytosis

The recommended dosage for systemic mastocytosis may vary depending on the individual’s age, weight, and response to treatment. In general, the dosage may range from 400mg to 800mg of cimetidine per day, divided into two to four doses. The maximum daily dose should not exceed 2.4 grams per day, unless directed by a healthcare provider.

Factors That Affect Dosage

Several factors may influence the recommended dosage of cimetidine. Age, weight, and medical conditions such as liver or kidney disease may affect how the body metabolizes the medication. Additionally, cimetidine may interact with other medications, such as anticoagulants and antidepressants, which can affect the dosage and frequency of administration.

Risks of Incorrect Dosage

Taking too much or too little cimetidine can have adverse effects on the body. For example, taking a higher dosage than recommended can increase the risk of side effects such as dizziness, headache, diarrhea, and constipation. On the other hand, taking a lower dosage than prescribed can reduce the effectiveness of the medication and fail to alleviate symptoms.

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