Domperidone Side Effects

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Written by BFH Staff Writer on February 19, 2024

When it comes to managing gastrointestinal issues like nausea, vomiting, and bloating, domperidone is often prescribed to provide relief. However, like any medication, it’s essential to understand potential side effects to make informed decisions about your health. 

What is Domperidone?

Domperidone is a medication commonly used to treat symptoms such as nausea, vomiting, bloating, and feelings of fullness in people with gastrointestinal disorders. It works by blocking the action of dopamine in the brain and gastrointestinal tract, which helps to improve the movement or contractions of the stomach and intestines, ultimately relieving symptoms.

Common Side Effects

While domperidone can be effective in managing gastrointestinal symptoms, it’s essential to be aware of potential side effects. Some common side effects that you may experience include:

  1. Headache – You might experience headaches as a common side effect of domperidone. If you find yourself experiencing persistent or severe headaches while taking this medication, it’s important to consult your healthcare provider.
  2. Dry Mouth – Dry mouth can occur as a result of taking domperidone. Staying hydrated and using sugar-free candies or gum can help alleviate this discomfort.
  3. Abdominal Cramps – Some individuals may experience abdominal cramps or discomfort while taking domperidone. These symptoms are usually mild and temporary but should be reported to your doctor if they persist or worsen.
  4. Dizziness – Dizziness is another potential side effect of domperidone. It’s essential to avoid activities that require alertness, such as driving or operating machinery, if you experience dizziness while taking this medication.
  5. Changes in Heart Rate – Domperidone can sometimes cause changes in heart rate, including palpitations or irregular heartbeats. If you notice any unusual heart-related symptoms while taking this medication, seek medical attention promptly.

Serious Side Effects

While less common, domperidone can also cause more severe side effects that require immediate medical attention. These may include:

  1. Allergic Reactions – In rare cases, domperidone can trigger allergic reactions such as rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing. If you experience any of these symptoms, seek emergency medical help.
  2. Seizures – Although uncommon, domperidone may increase the risk of seizures in some individuals, particularly those with a history of seizure disorders. If you have a seizure while taking this medication, seek medical attention immediately.
  3. Galactorrhea – Some individuals may experience an unusual side effect called galactorrhea, which involves the spontaneous flow of milk from the nipples unrelated to breastfeeding. If you notice this symptom, consult your healthcare provider.

Conclusion

Domperidone is a valuable medication for managing gastrointestinal symptoms, but like any medication, it can have side effects. By being aware of the potential side effects and knowing when to seek medical attention, you can use domperidone safely and effectively to improve your quality of life. Remember always to follow your healthcare provider’s instructions and report any concerns or unusual symptoms promptly.

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