3TC

3TC (Lamivudine) is an antiviral medication used to treat HIV-1 and chronic hepatitis B. It belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class, which works by stopping the virus from multiplying. This helps reduce viral load and improves immune function. 3TC is commonly used alongside other antiretroviral medications for effective HIV treatment.

Benefits

• Helps reduce HIV viral load and slows disease progression when combined with other medications.
• Controls hepatitis B by suppressing viral replication and reducing liver damage.
• Is well-tolerated with minimal drug interactions.
• Offers convenient dosing options with once or twice daily administration for improved treatment adherence.

Dosage

• For HIV treatment, adults and children over 12 years typically take 300 mg once daily or 150 mg twice daily, combined with other HIV medications.
• For children between 3 months and 12 years, the standard dose is 4 mg/kg twice daily, up to a maximum of 300 mg per day.
• For hepatitis B treatment, adults generally take 100 mg once daily.
• Pediatric dosages depend on medical guidance.
• This medication is taken orally, with or without food.

Warnings and Precautions

• Should always be used with other antiretroviral medications to prevent resistance.
• May cause a rare but serious condition called lactic acidosis, especially in patients with liver disease.
• Stopping treatment may cause severe liver complications in patients with hepatitis B, so liver function must be monitored.
• Dose adjustments may be needed for patients with kidney issues.
• Should be avoided in individuals allergic to lamivudine or any inactive ingredients.

Usage Instructions

• Take exactly as prescribed to prevent drug resistance.
• Swallow tablets whole with water. A liquid formulation is available if needed.
• Can be taken with or without food.
• If a dose is missed, take it as soon as possible unless it is close to the next dose. Do not take a double dose.

Storage Information

• Store at 25°C (77°F) and keep in a dry place, away from moisture and direct sunlight.
• Short-term exposure to temperatures between 15°C and 30°C (59°F–86°F) is acceptable.
• Protect liquid formulations from freezing.

Common Side Effects

• Mild side effects may include headache, nausea, fatigue, diarrhea, cough, and nasal congestion.
• Serious side effects that require medical attention include symptoms of lactic acidosis such as weakness, difficulty breathing, and irregular heartbeat, as well as severe liver issues or pancreatitis, which may present as abdominal pain and vomiting.