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Alphagan P® Ophthalmic Solution for Open-Angle Glaucoma
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Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
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Price range: $38.99 through $69.09
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This prescription eye drop helps lower pressure inside the eye. It is used for open-angle glaucoma and ocular hypertension. You can order with US delivery from Canada, and many people look for options when paying without insurance.
What Alphagan P® Is and How It Works
Alphagan P Ophthalmic Solution is a selective alpha-2 adrenergic agonist. It helps reduce intraocular pressure by decreasing aqueous humor production and by increasing uveoscleral outflow. The mechanism may support optic nerve protection when pressure is controlled, according to official labeling.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
The treatment is typically added to a glaucoma care plan when a single agent is not enough, or used alone when appropriate. It can be used alongside other topical agents as directed by your prescriber. Follow the official label and your clinician’s guidance for safe use.
Who It’s For
This medicine is indicated to lower eye pressure in adults with Open Angle Glaucoma or Ocular Hypertension. People who are sensitive to brimonidine or any ingredients should not use it. Infants and very young children must not receive this product due to serious safety risks noted in labeling.
If Brimonidine eye drops cost affects your choice of therapy, discuss alternatives and generic pathways with your prescriber. People using soft contact lenses should remove them before dosing and wait 15 minutes before reinsertion. Tell your clinician about cardiovascular disease, depression, orthostatic hypotension, or reduced kidney or liver function.
Dosage and Usage
Standard labeled dosing is one drop in the affected eye or eyes three times daily, about eight hours apart. Wash your hands before use. Tilt your head back, pull down the lower eyelid to form a pocket, and place one drop into the pocket without touching the tip to the eye or skin. Close the eye gently.
To reduce systemic absorption, press a finger at the inner corner of the eye for one minute after instillation. If you use other eye medications, wait at least five minutes between products. Use the schedule set by your prescriber and the official label. For broader eye-care options, browse Ophthalmology.
Strengths and Forms
This medicine is available as an ophthalmic solution in two commonly published strengths: 0.1% and 0.15%. Typical retail presentations include preservative-containing bottles, often supplied in 5 mL sizes. Availability can vary by partner pharmacy and market.
- Ophthalmic solution in multi-dose bottles
- Common pack sizes include 5 mL
- Check current availability before you place an order
Missed Dose and Timing
If you miss a scheduled dose, use it when you remember. If it is close to the next scheduled time, skip the missed dose and continue with your normal plan. Do not double up to make up for a missed application. Keep a simple reminder system to help maintain consistency.
Storage and Travel Basics
Store the bottle at room temperature, away from excess heat and direct light. Keep the cap tightly closed and the tip clean. Do not freeze the solution. Keep all eye medications out of the reach of children and pets.
When traveling, carry your bottle in a protective case in your hand luggage. Keep the original labeled carton for identification at security checkpoints. Avoid leaving the drops in a hot car or in freezing conditions. If you use a weekly pill or medication organizer, add a calendar note to help you pack your eye drops. For country-of-origin details on some items we carry, you can review Canada listings.
Pen Handling and Sharps Disposal
No pen, injector, or sharps handling is required for this ophthalmic solution.
Benefits
This class can lower eye pressure when used as directed. The dropper format is familiar and quick to use, which may support adherence. It can be combined with other agents when your care team recommends a multi-drug plan. The formulation is designed for ocular use and includes a well-studied active ingredient used in glaucoma management.
Side Effects and Safety
- Eye redness or irritation
- Burning or stinging after instillation
- Blurred vision
- Dry mouth
- Headache
- Drowsiness or fatigue
Serious reactions are uncommon but can include allergic eye reactions, very low blood pressure, slow heart rate, or mood changes. Stop use and seek medical help if you notice signs of an allergic reaction, severe eye pain, or marked vision changes. Use caution when driving until you know how the drops affect you. Children and infants are at higher risk of adverse events and should not use this product unless specifically directed by a specialist.
Drug Interactions and Cautions
Tell your prescriber about all medicines and supplements you use. Interactions may occur with monoamine oxidase inhibitors, tricyclic antidepressants that affect norepinephrine, CNS depressants, alcohol, and blood pressure medications. Using multiple pressure-lowering eye drops together can increase effects; follow the schedule your clinician provides. Remove soft contact lenses before dosing and wait 15 minutes before reinserting.
What to Expect Over Time
Many people experience a reduction in eye pressure with regular use, but your outcome depends on the overall treatment plan. Your clinician may check pressure at follow-up visits and adjust therapy when needed. Keeping a steady dosing routine, spacing drops correctly, and attending scheduled visits can help your care team evaluate progress.
Compare With Alternatives
Other approved options for pressure control include a prostaglandin analog and a carbonic anhydrase inhibitor. Depending on your medical history, a clinician may suggest one of these instead of, or alongside, the current therapy.
Two common alternatives we also carry are Xalatan Ophthalmic and Azopt. Your prescriber will decide which approach best fits your situation.
Pricing and Access
We list transparent options so you can review Alphagan P price and compare pack sizes before you proceed. Canadian pricing may offer meaningful cash-pay value for some patients. Ships from Canada to US when you place a valid prescription order.
You can also Order Alphagan P online after your prescriber sends or approves your script. We support secure checkout with encrypted payment processing. If you are looking for a coupon, see current offers on our Promotions page.
Availability and Substitutions
Supply can vary by strength and bottle size. If your preferred pack is unavailable, your prescriber may recommend an equivalent alternative or a temporary substitution in the same class. If paying cash, some patients discuss Alphagan P without insurance with their clinician to weigh brand and generic options.
Related options in this category include fixed-combination choices and single agents that target pressure through different mechanisms. You can also review agents like Dorzolamide Timolol or single agents such as Timolol Maleate and Dorzolamide when appropriate.
Patient Suitability and Cost-Saving Tips
Good candidates can administer drops consistently, keep follow-up appointments, and communicate about side effects. People with severe cardiovascular disease, those taking MAOIs, or caregivers of young children should discuss specific risks with a healthcare professional. Contact lens users should plan dosing around lens wear.
To manage cash-pay impact, ask your prescriber about generic brimonidine when clinically appropriate. If comparing plans, consider multi-month supplies to reduce per-fill fees, and set refill reminders so you do not run out unexpectedly. For some patients, Brimonidine tartrate price comparisons help guide therapy decisions in coordination with the care team.
Questions to Ask Your Clinician
- Is this the right pressure-lowering class for my eyes?
- How should I time doses with other drops?
- What signs of irritation mean I should contact you?
- Can I use this with my current blood pressure medicines?
- Will contact lenses affect safety or comfort?
- How soon should we recheck eye pressure?
- Are there alternatives if redness or fatigue occurs?
Authoritative Sources
FDA DailyMed for full U.S. prescribing information
Health Canada DPD product database
Manufacturer Information for updated label resources
Learn more about treatment choices in glaucoma care by exploring Alternatives To Combigan and other educational resources on our site.
Drug Class Insights and Further Reading
Carbonic anhydrase inhibitors and prostaglandin analogs are often used in combination plans. Your prescriber may consider agents based on pressure targets, tolerability, and dosing convenience. Educational content can help you understand these classes while you prepare for clinic visits.
For broader condition education, you can also review category pages for Open Angle Glaucoma and Ocular Hypertension.
Ready to proceed? Place your order with prompt, express shipping and reliable US shipping from Canada. This page is informational and is not a substitute for medical advice; always follow your prescriber’s directions.
Express Shipping - from $25.00
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Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
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- Worldwide (excludes some countries***)
What is the difference between Alphagan and Alphagan P?
Alphagan P contains a different preservative system that may be less irritating for people with sensitive eyes or long-term use compared to regular Alphagan.
Can I use Alphagan P while wearing contact lenses?
No. You should remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them.
What should I do if I accidentally use more than the recommended dose of Alphagan P?
If you use too many drops or overdose, seek medical advice immediately, especially if you experience drowsiness or low blood pressure.
How long will I need to use Alphagan P?
Many people need to use Alphagan P long-term to keep eye pressure under control. Your doctor will monitor your condition and advise how long you should continue treatment.
Can Alphagan P affect my ability to drive or use machines?
Yes. Alphagan P may cause blurred vision or drowsiness right after use. Wait until these effects pass before driving or using machines.
How quickly do these eye drops start to lower eye pressure?
Many patients experience pressure reduction after starting therapy, but the response varies. Your clinician will generally assess progress over follow-up visits and may adjust the plan. Use the drops on schedule, space different eye medicines by at least five minutes, and practice punctal occlusion to limit systemic exposure. Do not change dosing without your prescriber’s advice. Report persistent irritation, vision changes, or new symptoms promptly so your care team can evaluate safety and effectiveness in your specific case.
Can I use this with my contact lenses?
Yes, but remove soft lenses before dosing. Instill one drop, then wait at least 15 minutes before reinserting lenses. This helps avoid lens discoloration and improves comfort. Wash hands before use, and avoid touching the dropper tip to the eye or any surface. If you experience ongoing redness or irritation with lenses, talk with your eye care professional about timing adjustments or alternative options.
What if I miss a dose?
Use a missed dose when you remember, unless it is nearly time for the next scheduled application. If so, skip the missed dose and resume your regular plan. Do not double doses. Consider setting reminders on your phone to help maintain consistency. If you frequently miss doses, discuss strategies with your clinician to improve adherence and keep pressure control on track.
Are there medicines that interact with this treatment?
Potential interactions include monoamine oxidase inhibitors, tricyclic antidepressants that affect norepinephrine, CNS depressants, alcohol, and some blood pressure medicines. Using multiple pressure-lowering eye drops together may lead to additive effects. Share a full medication list with your clinician, including over-the-counter products and supplements, so they can review safety and provide a dosing schedule that fits your regimen.
Is this suitable during pregnancy or breastfeeding?
Safety data are limited in pregnancy and while breastfeeding. Your prescriber will weigh potential risks and benefits and may suggest alternatives if needed. Minimize systemic exposure by using punctal occlusion after dosing. Never start or stop medicines in pregnancy or while nursing without medical guidance. If you are planning pregnancy, discuss your glaucoma plan in advance so adjustments can be made safely.
How should I store the bottle at home and when traveling?
Keep the bottle at room temperature, away from excess heat and light. Do not freeze. Keep the cap tightly closed and the dropper tip clean. When traveling, carry the medication in your hand luggage, avoid extreme temperatures, and bring the original labeled carton for security checks. Keep all eye medicines out of the reach of children. Replace the bottle if the solution becomes discolored or cloudy.
What are common side effects?
The most reported effects include eye redness, stinging or burning after dosing, blurred vision, dry mouth, headache, and fatigue. These are usually mild and short-lived. Serious reactions are uncommon but can include allergic eye reactions, very low blood pressure, slow heart rate, or mood changes. Seek medical care if you develop severe eye pain, significant vision changes, or swelling. Report persistent symptoms to your clinician for personalized guidance.
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