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Reyataz® Capsules for HIV-1
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Atazanavir is an HIV protease inhibitor used with other antiretrovirals. It helps lower viral load as part of a complete regimen prescribed by your clinician. This page explains how the medicine works, who it suits, and ways to manage treatment and access.
What Reyataz Is and How It Works
With US delivery from Canada, you can access this treatment through our platform. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing. The active ingredient blocks the HIV-1 protease enzyme. That action prevents maturation of new viral particles. The therapy is taken with other HIV medicines to support viral suppression. Many patients pay cash for Atazanavir without insurance when coverage is limited or deductibles are high.
It is usually given once daily with food. It may be used with a booster such as ritonavir or cobicistat based on the label and prescriber direction. Always follow the official prescribing information provided with your medicine.
Who It’s For
This medicine is indicated for adults and certain adolescents with HIV-1 infection, in combination with other antiretrovirals. Some patients start therapy after baseline labs and genotype testing. Others switch from another regimen when appropriate. Reyataz brand Atazanavir should not be used in patients with known hypersensitivity to atazanavir. People with moderate to severe liver problems may not be candidates. Those with a history of heart conduction issues should discuss risks. For broader context on condition care, see our HIV category and this overview of testing methods in HIV Test Types.
Dosage and Usage
Follow your prescriber’s instructions and the package insert. Standard adult regimens often use once-daily dosing with food. When a booster is prescribed, take both medicines together at the same meal. Swallow capsules whole with water. If your clinician advises an acid-reducing agent, spacing may be required. Proton pump inhibitors and H2 blockers can affect absorption; clinical guidance varies by experience status and booster use. Defer to the official label or your healthcare professional for specifics.
If you start or stop other medicines, inform your prescriber promptly. Take doses at the same time every day to support adherence. If you miss several doses, do not try to “catch up”; contact your clinician for advice. For pediatric or weight-based dosing, see the full prescribing information.
Some adults take a dose that aligns with Atazanavir 300 mg capsules when combined with a pharmacokinetic enhancer, per label. Your clinician will confirm your schedule.
Strengths and Forms
Common presentations include capsules for adults and an oral powder for pediatric patients. Available strengths include 150 mg, 200 mg, and 300 mg capsules. Availability may vary by manufacturer and market. The oral powder is typically mixed as directed and taken with food; caregivers should review label instructions before use.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember unless it is close to the time of your next dose. Do not take two doses at once. If vomiting occurs shortly after taking the medicine, check the package insert or contact your healthcare professional for guidance. Aim for consistent daily timing with a meal, which supports absorption and may reduce stomach upset.
Storage and Travel Basics
Store capsules at room temperature in a dry place, away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Do not transfer pills to unlabelled containers. When traveling, carry your medication in original packaging with the prescription label. Pack it in your carry-on to avoid temperature extremes and lost luggage. Keep a copy of your prescription and a medication list in case you need to speak with a clinician while away.
Benefits
This protease inhibitor can help maintain viral suppression as part of a complete antiretroviral regimen. Once-daily dosing with food may fit many routines. A long track record and flexible pairing with other agents provide prescribers with familiar options. For people looking to simplify schedules, a single daily dose can aid adherence when clinically suitable.
Side Effects and Safety
- Common: nausea, diarrhea, headache, abdominal pain
- Skin: mild rash can occur
- Eyes/skin: yellowing from benign bilirubin increases
- General: fatigue, insomnia
Serious but less common risks include significant skin reactions, liver problems, gallstones, kidney stones, and heart conduction changes (PR interval prolongation). Inform your prescriber immediately if you notice severe rash, jaundice with pain, dark urine, chest symptoms, or signs of an allergic reaction. Immune reconstitution may occur when starting combination antiretroviral therapy.
Drug Interactions and Cautions
Atazanavir is metabolized by CYP3A. Strong inducers (such as rifampin or St. John’s wort) can reduce levels and are generally contraindicated. Some statins, antiarrhythmics, benzodiazepines, and ergot derivatives may require avoidance. Acid-reducing agents can lower absorption; timing and maximum doses depend on whether a booster is used and on treatment experience. Tenofovir may influence exposures; clinicians often consider corresponding adjustments within the regimen. Discuss all medicines, vitamins, and herbal products with your prescriber. For perspective on alternative HIV options, see this article: Aptivus Guide.
What to Expect Over Time
With consistent daily use in a complete regimen, many people see improved lab results at routine monitoring visits. Your clinician will track viral load and CD4 counts, and check liver function, bilirubin, and renal labs as needed. Some side effects appear early and fade as your body adjusts. Keep taking your medicine as prescribed unless your prescriber tells you to stop. If diet changes or interacting medicines are needed, your care team will advise on timing strategies.
Education and support matter. Reading about other options can help you prepare for discussions; see our overview in Biktarvy Guide.
Compare With Alternatives
Other options in HIV care depend on resistance patterns, prior therapy, and tolerability.
- Pifeltro: Doravirine is a non-nucleoside option for certain adults; learn more at Pifeltro.
- Atazor 300mg: Some patients may receive an atazanavir product from a different manufacturer when appropriate; see Atazor 300mg.
Discuss the best regimen for your situation with your prescriber.
Pricing and Access
We offer Canadian pricing with reliable fulfilment that Ships from Canada to US. Check the Generic Atazanavir price on our product page and compare options. If you plan to Buy Atazanavir online, you can complete checkout and upload your prescription. For coupons and seasonal offers, visit Promotions. Our encrypted checkout protects your information during payment.
Availability and Substitutions
Stock and manufacturers can change. If a specific strength or package is unavailable, a prescriber may recommend a therapeutically appropriate alternative or a different manufacturer. Some adults use capsule strengths aligned with Atazanavir 300 mg capsules when clinically indicated. Your care team will determine the right option.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults who can take a once-daily protease inhibitor with food and who have no contraindicated interactions. It may not suit those with significant hepatic impairment or certain cardiac conduction abnormalities. To reduce out-of-pocket costs, consider multi-month fills if your prescriber agrees. Set refill reminders so you do not miss doses. Ask your clinician about lab timing to bundle tests and visits efficiently. If insurance changes, check cash-pay options and compare Canadian pricing in our Antivirals category.
Questions to Ask Your Clinician
- Baseline labs: Which tests do you want before starting?
- Regimen fit: Is a booster recommended in my case?
- Acid reducers: How should I time antacids or PPIs?
- Interactions: Are any of my medicines unsafe with this therapy?
- Side effects: What symptoms should prompt a call?
- Monitoring: How often will you check my liver and bilirubin?
- Travel: What documentation should I carry for international trips?
Authoritative Sources
Health Canada Product Monograph
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Can I take atazanavir with antacids or acid reducers?
No, acid-reducing medications like proton pump inhibitors and antacids can affect atazanavir absorption. Speak with your doctor about timing doses if acid reducers are necessary.
What should I do if I miss a dose?
Take the missed dose as soon as you remember, but if it is close to your next scheduled dose, skip it. Do not take a double dose.
Can atazanavir cause jaundice?
Yes, atazanavir can increase bilirubin levels, which may cause yellowing of the skin or eyes. This is usually harmless but should be discussed with your doctor.
Is atazanavir safe during pregnancy?
Atazanavir may be used during pregnancy under a doctor’s supervision. Your healthcare provider will determine if the benefits outweigh the risks.
Can I drink alcohol while taking atazanavir?
Alcohol may increase the risk of liver problems while on atazanavir. It is best to limit or avoid alcohol consumption and discuss any concerns with your doctor.
Can I take this medicine during pregnancy or while breastfeeding?
Use in pregnancy and breastfeeding should be individualized. Some protease inhibitors may be considered with careful monitoring. Your clinician will weigh benefits and risks, including viral load, resistance, and alternative regimens. Drug levels can change during pregnancy, and infant exposure through breast milk is a concern. Follow public health recommendations about breastfeeding with HIV. Review the latest label and perinatal guidelines with your healthcare professional.
Do acid-reducing medicines affect this treatment?
Yes. Proton pump inhibitors, H2-receptor antagonists, and antacids can reduce absorption by increasing gastric pH. Timing and maximum doses may depend on whether a booster is used and on prior treatment history. Your prescriber may recommend spacing or choosing a different acid reducer. Always review the label or consult your clinician before starting or changing these medicines.
What foods should I take it with, and does timing matter?
Take your dose with food at about the same time each day. A meal can improve absorption and may reduce stomach upset. Choose a routine that you can maintain daily. Avoid grapefruit or Seville oranges if your clinician advises due to interaction potential with some antiretrovirals. If nausea occurs, smaller meals or snacks may help. Do not skip doses to prevent resistance.
Can I open or crush the capsules if I have trouble swallowing?
Do not crush or open capsules unless the label explicitly allows it. Changing the form can alter absorption and effectiveness. If you have difficulty swallowing, ask your prescriber about the pediatric oral powder option or a different regimen that suits your needs. A pharmacist can also discuss administration aids, like pill-swallowing techniques, that avoid altering the capsule.
Which lab tests will my clinician monitor?
Clinicians often monitor HIV-1 RNA, CD4 cell count, liver enzymes, bilirubin, renal function, and sometimes ECG if there are cardiac concerns. Additional labs may be ordered based on symptoms or interacting medicines. Early in therapy, your prescriber may check labs to establish baselines and to assess tolerability. Ongoing monitoring helps confirm the regimen is working safely alongside your other treatments.
How does this medicine interact with other HIV drugs like tenofovir?
Interactions within antiretroviral regimens are common. Atazanavir exposure can be affected by tenofovir, and boosters like ritonavir or cobicistat change drug levels. Prescribers consider these factors when selecting doses and companions. Never adjust your own regimen. Bring a full medication list to visits so potential interactions can be reviewed and managed according to the label and treatment guidelines.
What should I do if I notice yellowing of skin or eyes?
Yellowing may be from unconjugated bilirubin increases associated with this drug class. Although often benign, new or worsening jaundice warrants calling your clinician. Sudden severe symptoms, abdominal pain, dark urine, or pale stools need prompt evaluation to rule out liver or gallbladder issues. Do not stop the medicine without medical advice; your prescriber will guide next steps based on labs and symptoms.
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