Please note: a valid prescription is required for all prescription medication.
Daxas is an oral COPD medicine containing roflumilast, a phosphodiesterase-4 inhibitor used for flare-up prevention in selected adults. You can buy Daxas 500 mcg tablets online, view the current Daxas price, and choose the strength shown during ordering to match the directions from your healthcare professional.
This medicine is used as a long-term add-on treatment for severe chronic obstructive pulmonary disease associated with chronic bronchitis and a history of exacerbations. It is not a rescue medicine and will not quickly open the airways during sudden shortness of breath.
Daxas Price, Strength, and Ordering Basics
Daxas 500 mcg is the strength commonly associated with roflumilast tablet therapy for COPD maintenance. During checkout, select the dose, quantity, and supply that match your clinical directions. If the label on your medicine or your care plan uses different wording, ask a healthcare professional to clarify before you place an order.
The Daxas cost can vary with sourcing, supply, quantity, and manufacturer changes. Many people paying out of pocket look at Daxas Canadian pricing when insurance coverage is limited or unavailable. The current total is shown during ordering before payment, so you can review the medicine cost alongside any service and delivery charges.
Quick tip: Keep a copy of your current medication list nearby when ordering, especially if you use several COPD inhalers or tablets.
What Daxas Is Used For
Daxas is used to reduce the risk of COPD exacerbations in adults with severe COPD linked with chronic bronchitis and a history of flare-ups. An exacerbation is a worsening of COPD symptoms that may require additional treatment, urgent care, or changes to your maintenance plan. For more condition background, visit our chronic obstructive pulmonary disease COPD information.
Roflumilast works differently from inhaled bronchodilators. Bronchodilators help relax airway muscles, while roflumilast helps reduce inflammation involved in COPD flare-ups. Because it does not provide fast relief, continue to use any rescue inhaler exactly as directed by your clinician.
This treatment is not intended for asthma, sudden breathing attacks, or occasional breathlessness. It is usually considered when COPD remains difficult to control despite appropriate maintenance therapy. Your clinician may look at your exacerbation history, lung function, body weight, mood history, liver health, and current medicines before deciding whether roflumilast fits your plan.
How Roflumilast Helps the Lungs
Roflumilast is a PDE4 inhibitor. PDE4 is an enzyme involved in inflammatory signaling, and blocking it can reduce certain inflammatory activity in the airways. In COPD care, the goal is fewer flare-ups over time rather than immediate improvement after each tablet.
Daxas is an oral anti-inflammatory medicine, not a steroid and not an inhaler. That distinction matters because it may be added to inhaled COPD maintenance treatment rather than replacing it. Many adults who use roflumilast still need long-acting bronchodilators, inhaled corticosteroids, or combination inhalers as directed.
Consistency matters with preventive COPD therapy. Taking the tablet at the same time each day can make the routine easier. If you also use inhalers, technique and adherence remain important parts of control; our respiratory articles cover practical lung-health topics that may support conversations with your care team.
How to Take Daxas Tablets
The usual schedule for roflumilast tablets is once daily, with or without food. Swallow tablets whole with water. If stomach upset occurs, taking the dose with food may be easier, but do not change the prescribed routine without clinical guidance.
If you miss a dose, take it when you remember on the same day. If it is nearly time for the next dose, skip the missed dose and return to the regular schedule. Do not take two doses together to make up for a missed tablet.
Daxas is designed for long-term control. You may not feel a change in breathing right away, and that does not necessarily mean the medicine is not working. Track flare-ups, rescue inhaler use, weight changes, sleep changes, appetite, and mood so your clinician can judge whether the treatment remains appropriate.
Safety, Side Effects, and Monitoring
Common side effects can include diarrhea, nausea, stomach pain, reduced appetite, weight loss, headache, insomnia, and dizziness. Some effects are most noticeable early in treatment and may lessen as the body adjusts. Contact a healthcare professional if symptoms persist, feel severe, or interfere with eating, sleeping, hydration, or daily activities.
Roflumilast can be associated with psychiatric side effects, including anxiety, depression, mood changes, and suicidal thoughts or behavior. This risk is especially important for people with a history of depression or suicidal thinking. Seek urgent help for severe mood symptoms, thoughts of self-harm, or behavior changes that worry you or those close to you.
Weight loss can occur with roflumilast. Your healthcare professional may monitor body weight and appetite, especially if you are already underweight or have unexplained weight loss. Report meaningful weight changes promptly rather than waiting for the next routine visit.
Daxas should be avoided in moderate to severe liver impairment. Hypersensitivity reactions are possible with any medicine; get medical help for rash, swelling, wheezing, or trouble breathing after taking a tablet. Tell your clinician about all medicines, supplements, and herbal products you use so interaction risks can be assessed.
Interactions and What to Avoid
Strong enzyme-inducing medicines may reduce roflumilast exposure and make it less effective. Examples include rifampin, carbamazepine, phenobarbital, and phenytoin. Some inhibitors may increase exposure and raise the chance of side effects, including certain antibiotics or medicines that affect the same liver pathways.
Discuss theophylline, other COPD medicines, antidepressants, antifungals, antibiotics, seizure medicines, and tuberculosis treatments before starting roflumilast. Alcohol is not listed as a direct contraindication, but it can worsen dizziness, sleep problems, stomach effects, or mood symptoms in some people. Ask a clinician what level of alcohol intake is appropriate for your health history.
Do not stop COPD maintenance medicines on your own because symptoms feel stable. Stopping inhalers, skipping follow-ups, or ignoring early mood or weight changes can make treatment harder to manage. If side effects are difficult, a clinician can help weigh whether to continue, pause, or switch therapy.
Storage, Travel, and US Shipping from Canada
Store Daxas tablets at typical room temperature in a dry place. Keep tablets in the original labeled packaging when possible, away from bathroom humidity, children, and pets. Do not use tablets that look damaged, contaminated, or inconsistent with the packaging label.
When traveling, carry tablets in hand luggage with your medication list and clinic contact information. Keeping medicine in the labeled container helps avoid confusion at security checks, hotels, or urgent care visits. If your supply crosses time zones, ask how to keep a simple once-daily schedule.
BorderFreeHealth offers US shipping from Canada for this product, with prompt, express shipping. Country-of-origin information can be browsed through our Canada sourcing section, and broader respiratory medicines are grouped under the respiratory category.
Daxas Compared With COPD Inhalers
Daxas occupies a different role than many COPD inhalers. Long-acting muscarinic antagonists, long-acting beta agonists, and inhaled corticosteroid combinations mainly support airway opening and airway inflammation control through inhaled delivery. Roflumilast is an oral PDE4 inhibitor focused on reducing exacerbation risk in a narrower COPD group.
That difference does not make one approach universally better. A person with chronic bronchitis and repeated flare-ups may need a different plan than someone whose main issue is day-to-day breathlessness. Your clinician may combine therapies, adjust inhalers, add pulmonary rehabilitation, or address smoking cessation, vaccination, oxygen needs, and exercise tolerance.
Why it matters: Daxas should not replace a rescue inhaler for sudden breathing symptoms.
Who May Need Extra Caution
Daxas may not be suitable for everyone with COPD. Extra caution is important for people with moderate or severe liver problems, a history of depression, suicidal thoughts, significant unintentional weight loss, frailty, or multiple interacting medicines. Older adults and people with several chronic conditions may need closer monitoring after therapy begins.
Pregnancy, breastfeeding, and plans for pregnancy should be discussed with a clinician before using roflumilast. COPD itself can carry risks when breathing is poorly controlled, so treatment decisions should balance maternal health, symptom control, and medicine-specific safety information.
Call a healthcare professional if you develop persistent diarrhea, severe nausea, ongoing insomnia, new anxiety, low mood, appetite loss, unexpected weight change, allergic symptoms, or worsening breathing. Seek emergency help for severe shortness of breath, chest pain, blue lips, confusion, or thoughts of self-harm.
Questions to Discuss Before Starting or Refilling
- Is roflumilast appropriate for my COPD type and flare-up history?
- Which inhalers should I keep using while taking this tablet?
- How often should my weight and mood be monitored?
- Which side effects should prompt a call right away?
- Could my seizure medicine, antibiotic, antidepressant, or theophylline interact?
- What should I do if diarrhea or appetite loss becomes persistent?
- How will we decide whether the medicine is helping over time?
Authoritative Sources
European Medicines Agency: Daxas medicine information
AstraZeneca Canada: Daxas product monograph
This content is for informational purposes only and is not a substitute for professional medical advice.
BMI Calculator
Estimate adult body mass index from height and weight, with metric and imperial units.
These calculations are for education only and do not replace clinical advice, diagnosis, or treatment. Always confirm medical decisions with a qualified healthcare professional.
Peak Flow Zone Calculator
Calculate asthma peak-flow zones from personal best and current peak flow.
These calculations are for education only and do not replace clinical advice, diagnosis, or treatment. Always confirm medical decisions with a qualified healthcare professional.
Pack-Years Calculator
Estimate smoking exposure from cigarettes per day and years smoked.
These calculations are for education only and do not replace clinical advice, diagnosis, or treatment. Always confirm medical decisions with a qualified healthcare professional.
Target Heart Rate Calculator
Estimate exercise heart-rate zones using age, resting heart rate, and the Karvonen method.
These calculations are for education only and do not replace clinical advice, diagnosis, or treatment. Always confirm medical decisions with a qualified healthcare professional.
Express Shipping - from $29.99
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $29.99
- Cold-Packed Products $39.99
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $19.99
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $19.99
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
What is Daxas used for?
Daxas is used as maintenance treatment to reduce COPD exacerbations in selected adults with severe COPD associated with chronic bronchitis and a history of flare-ups. It is not used for sudden breathing symptoms or asthma attacks.
What does roflumilast do for the lungs?
Roflumilast blocks PDE4, an enzyme involved in inflammatory signaling. In COPD, this anti-inflammatory effect can help reduce flare-up risk over time, but it does not work like a rescue bronchodilator.
Can Daxas cause depression or mood changes?
Yes. Roflumilast has been associated with mood changes, depression, anxiety, insomnia, and suicidal thoughts or behavior. Contact a healthcare professional promptly for new or worsening mood symptoms, and seek urgent help for thoughts of self-harm.
What should I avoid while taking roflumilast?
Avoid stopping COPD inhalers or changing your treatment routine unless a clinician tells you to. Discuss strong enzyme inducers such as rifampin, carbamazepine, phenobarbital, and phenytoin, because they may reduce roflumilast effectiveness.
Is Daxas the same as a rescue inhaler?
No. Daxas is an oral maintenance medicine for reducing COPD flare-up risk in appropriate adults. It does not provide rapid airway opening, so keep using your rescue inhaler as directed for sudden symptoms.
How should Daxas tablets be stored?
Store tablets at room temperature in a dry place, away from moisture, children, and pets. Keep them in the original labeled packaging when possible, especially during travel.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
