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Dienogest Tablets for Endometriosis
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$44.99
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This progestin helps manage endometriosis symptoms and supports hormonal balance. This page explains how the treatment works, who it suits, and how to use it, with US shipping from Canada. You can also review access options if you are paying without insurance.
What Dienogest Is and How It Works
Dienogest® is a progestin used to reduce endometrial tissue activity and relieve pelvic pain associated with endometriosis. It works by countering estrogen’s effects on endometrial cells, which may lessen inflammation and bleeding in ectopic tissue. Some combination oral contraceptives pair a progestin with an estrogen to prevent pregnancy; single-ingredient therapy focuses on endometriosis symptom control. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
The treatment is taken orally. It may change menstrual bleeding patterns. Many people notice lighter or irregular periods over time. For birth control needs, use a dedicated contraceptive method since this medicine alone is not approved as a contraceptive in all regions.
Learn more about the condition and management options in our Endometriosis hub, and explore related care in Womens Health.
Who It’s For
This therapy is intended for people diagnosed with endometriosis who need ongoing symptom relief. It can be considered for adults who prefer an oral, non-injectable option. It is not for use during pregnancy.
Avoid this medicine if you have active liver disease, hormone-sensitive cancers, unexplained uterine bleeding, current or previous blood clots, or allergy to any component. Those with depression, migraine, high blood pressure, diabetes, or high cholesterol should discuss risks with a prescriber. People seeking contraception may need a combined oral contraceptive or non-oral method; see our Contraception category.
Dosage and Usage
Typical endometriosis regimens use continuous daily dosing. Follow the official label and your prescriber’s directions for start day and duration. Take the tablet at the same time each day with water. You can take it with or without food, but pick a routine you can keep.
If your clinician prescribes dienogest 2 mg, do not change your schedule without medical guidance. Combined products have different schedules that follow the pack’s color or sequence. Read the patient leaflet for specific day-by-day instructions when using any combination pack.
Strengths and Forms
Common presentations include oral tablets. Availability may vary by supplier and country of origin.
- dienogest 2 mg tablets for endometriosis symptom management
- Combination oral contraceptives pairing a progestin with ethinyl estradiol or estradiol valerate (pack structures vary by brand)
Not all strengths or packs are available at all times. See country-of-origin details under product listings tagged Canada.
Missed Dose and Timing
If you miss a tablet, take it as soon as you remember on the same day. If it is almost time for the next tablet, skip the missed one and go back to your usual time. Do not double up. For combination packs, missed-pill rules differ; check the leaflet for backup contraception instructions.
Storage and Travel Basics
Store tablets at room temperature in the original blister or bottle. Protect from moisture and excess heat. Keep out of reach of children and pets. When traveling, carry your medicine in hand luggage with a copy of your prescription. Use a small pill organizer only if it preserves labeling you need for security checks. Do not use tablets that are damaged, discolored, or past the labeled date. Our checkout is encrypted for your security.
Benefits
This medicine may reduce pelvic pain, painful periods, and spotting between periods associated with endometriosis. Many people value a once-daily oral option. Continuous dosing can lessen cyclical pain by stabilizing endometrial activity. For those who cannot take estrogen-containing products, a progestin-only approach may provide an alternative path discussed with a clinician.
Side Effects and Safety
- Headache or migraine
- Breast tenderness
- Mood changes or low mood
- Acne or oily skin
- Nausea or abdominal discomfort
- Weight change
- Irregular or lighter bleeding
Serious effects are less common and can include severe depression, liver problems, allergic reaction, or, with estrogen-containing combinations, blood clots, stroke, or heart attack in susceptible users. Seek urgent care for chest pain, sudden shortness of breath, one-sided weakness, severe abdominal pain, or yellowing of the skin or eyes. Do not use in pregnancy. If you become pregnant, stop the medicine and contact your prescriber.
Drug Interactions and Cautions
Strong cytochrome P450 3A4 inducers may lower levels and reduce effectiveness. Examples include rifampin, carbamazepine, phenytoin, and St. John’s wort. Potent CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, and certain HIV/HCV medicines can increase exposure. Discuss all medicines and supplements with your healthcare professional.
Use caution if you have a history of depression, migraine with aura, high blood pressure, high triglycerides, diabetes, or liver conditions. Smoking increases cardiovascular risk with estrogen-containing contraceptives, especially over age 35. Alcohol can worsen certain side effects like dizziness or nausea.
What to Expect Over Time
With regular daily dosing, many patients report gradual reductions in pelvic pain and cycle-related symptoms. Irregular bleeding or spotting may occur early and often improves with continued use. Track symptoms and periods in a diary or app. Bring this record to follow-up visits so your prescriber can assess response and tolerability. If symptoms persist or worsen, your clinician may consider alternative therapies or additional evaluations.
Compare With Alternatives
Other options for endometriosis include combined oral contraceptives, levonorgestrel-releasing intrauterine systems, GnRH analogs or antagonists, and, in selected cases, surgery. Some COCs feature estradiol valerate and dienogest in multiphasic regimens. Explore broader options in our Endometriosis and Contraception categories. For vulvovaginal symptom relief in menopause care, see Imvexxy as an example of a local estrogen product; this is not an endometriosis treatment but can be relevant for select needs under clinician guidance.
Pricing and Access
Border Free Health lists cash-pay options with transparent details. Canadian pricing can offer meaningful savings compared with typical U.S. rates. This product Ships from Canada to US with pharmacist dispensing after prescription verification.
Looking to compare brands? Some users research Valette Dienogest or other regional equivalents; availability differs by market. To see current pricing and supply, add the item to your cart to view options. For seasonal discounts, check our Promotions page.
Availability and Substitutions
Supply can vary by strength and manufacturer. If your preferred pack is unavailable, your prescriber may recommend an equivalent alternative in the same class or a different therapy aligned to your history. We cannot guarantee restock dates. Review category pages like Womens Health for adjacent options and guidance articles.
Patient Suitability and Cost-Saving Tips
You may be a candidate if you have confirmed endometriosis and want a daily oral therapy. You may not be a candidate if pregnant, breastfeeding without approval, or if you have severe liver disease, certain cancers, or a clotting history. Adolescents and perimenopausal patients need individualized assessment.
- Plan multi-month fills: fewer refills can reduce overall costs
- Use reminders: set phone alerts to improve adherence
- Bundle needs: consolidate orders within Womens Health
- Travel prep: pack extra days and carry the prescription copy
Questions to Ask Your Clinician
- Is a progestin-only therapy appropriate for my symptoms and goals?
- How long should I continue before assessing response?
- What signs mean I should contact you right away?
- Could a combined oral contraceptive suit me better?
- Do my medicines or supplements interact with this therapy?
- What monitoring do I need for mood, blood pressure, or liver health?
Authoritative Sources
Health Canada DPD: Visanne (dienogest)
Health Canada DPD: Qlaira (estradiol valerate/dienogest)
Bayer: Visanne Product Information
Ready to get started? Add to cart and proceed to checkout for US delivery from Canada with prompt, express shipping. This content is for general information and does not replace your prescriber’s guidance.
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How long is this therapy usually taken for endometriosis?
Treatment duration varies based on your clinician’s plan, symptom control, and tolerability. Many patients use a continuous daily schedule over months. Follow-up visits help assess benefits and side effects, and guide whether to continue, pause, or switch therapies. Do not stop or extend treatment on your own. Use a symptom diary to capture pain, bleeding changes, and any mood changes for review at appointments.
Can this medicine be used for birth control?
Single-ingredient progestin products used for endometriosis are not approved as contraceptives in all regions. If you also want pregnancy prevention, discuss combined oral contraceptives or non-oral options with your prescriber. Combined products contain an estrogen plus a progestin and have different dosing schedules and missed-dose rules. Always refer to the specific package insert for contraceptive guidance.
What side effects should I watch for at the start?
Common effects include headache, breast tenderness, mild nausea, acne, and irregular bleeding. These often improve as your body adjusts. Call your clinician for severe mood changes, persistent migraine, yellowing of the skin or eyes, or signs of a clot with combination contraceptives such as chest pain or sudden shortness of breath. Report any new medicines or supplements you begin, since some can alter hormone levels.
What if I miss a tablet?
Take the missed tablet as soon as you remember on the same day. If it’s close to your next dose, skip the missed tablet and return to your normal time. Don’t double up. For combination packs, follow the missed-pill grid in the leaflet, which may advise backup contraception for a period of time. Consistent timing each day helps maintain steady hormone exposure and symptom control.
Are there important drug interactions?
Yes. Medicines that strongly affect CYP3A4 can change hormone exposure. Inducers like rifampin, carbamazepine, and St. John’s wort may reduce effectiveness. Inhibitors such as ketoconazole, itraconazole, and certain antivirals can increase levels. Always share a full list of prescription drugs, OTC products, and herbal supplements with your healthcare professional so they can check for interactions and adjust your plan if needed.
How should I store the tablets when traveling?
Keep tablets in the original labeled packaging at room temperature, away from moisture and heat. Pack them in your carry-on to avoid extreme temperatures in checked luggage. Bring a copy of your prescription and a simple dosing schedule. A small pill organizer can help, but retain identifying labels for security checks. Avoid using tablets that are damaged or past the date on the package.
Will this affect my periods or bleeding patterns?
Changes in bleeding are common, especially early in treatment. You may notice spotting, lighter periods, or altered cycle timing. These effects often lessen with continued use. Track your pattern and discuss it at follow-up visits. If bleeding becomes heavy or prolonged, contact your prescriber promptly. If you switch to a combined contraceptive, expect different patterns based on that product’s schedule and formulation.
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