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Dienogest (Prescription Progestin)
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Dienogest is a prescription progestin (progesterone-like hormone) used in selected hormone therapy plans and in some combined oral contraceptives. This page summarizes practical basics—common uses, dosing patterns, safety concerns, interactions, and storage—using plain language alongside clinical terms. Services arranged through BorderFreeHealth are fulfilled by partner pharmacies and Ships from Canada to US for cash-pay access, including people without insurance.
A valid prescription is required, and the exact directions depend on the specific product and country labeling. The information below is meant to support informed conversations with a prescriber and to help with non-clinical tasks like keeping medication lists, tracking refills, and storing tablets properly.
For related browsing, see the Women’s Health Products hub and the Women’s Health Articles collection for broader context on reproductive health topics.
What Dienogest Is and How It Works
This medicine is part of the progestin class, which can change how the uterine lining responds to hormones and can also affect ovarian hormone signaling. Prescriptions are confirmed with the prescriber before dispensing. Access may be coordinated as US delivery from Canada through licensed pharmacy partners, depending on the prescription and product availability.
In clinical terms, progestins bind progesterone receptors and may reduce estrogen-driven stimulation of endometrial tissue (the lining-like tissue involved in some gynecologic conditions). In everyday language, that can mean changes in bleeding patterns and hormone-related symptoms over time. Effects and side effects can look different when the progestin is used alone versus paired with an estrogen in a combined pill.
Why it matters: The same ingredient can be used in different products with different instructions.
Who It’s For
Whether this therapy is appropriate depends on the exact formulation being prescribed and the reason for use. In some settings, a clinician may prescribe a progestin-focused regimen for endometriosis-related symptoms, while other products use a progestin as one component of contraception. For condition-specific browsing on the site, see Endometriosis and Contraception.
Important exclusions and precautions vary by label, especially when an estrogen is part of the product. Common high-level reasons a prescriber may avoid hormone therapy include known or suspected pregnancy, unexplained vaginal bleeding, active liver disease, or a history of certain hormone-sensitive cancers. Combined hormonal contraceptives also carry additional clot-related cautions for some patients, so personal risk factors (smoking status, migraine with aura, prior thrombosis, and age) often influence product choice.
Dosage and Usage
Follow the prescription label and the patient leaflet for the specific product provided. Many hormone tablets are taken once daily at about the same time, which helps keep hormone levels steadier and reduces missed doses. If Dienogest is part of a multi-tablet pack or phased regimen, the order of tablets and the start day can matter, so packaging instructions should be read closely.
If a dose is missed, the correct next step depends on the product type and how long it has been since the scheduled dose. Some regimens advise taking the missed tablet as soon as remembered, while others recommend skipping it—especially for combined contraceptives where timing rules can change across the pack. When instructions are unclear or the leaflet is missing, the safest approach is to confirm directions with a pharmacist or prescriber rather than guessing.
For broader reproductive-health planning resources, the site’s maternal health overview in Maternal And Newborn Health may be helpful background reading.
Strengths and Forms
Most products are supplied as oral tablets, but the exact strength and packaging format depend on the manufacturer and the formulation being prescribed. Some monographs describe a Dienogest 2 mg tablet as a common single-hormone presentation, while other products combine an estrogen with a progestin in fixed-dose tablets and may use calendar-style packs to guide daily use. Availability through partner pharmacies can vary.
Branding and product names can differ by country and can include combined-hormone regimens as well as progestin-only options. The key practical point is that “tablet count” and “pack layout” may signal a different schedule, not just a different manufacturer. The prescription label and insert should always be treated as the source of truth for that specific supply.
| Presentation type | What to check on the label |
|---|---|
| Single-hormone tablets | Strength per tablet and daily timing instructions |
| Calendar or phased packs | Tablet order, start day, and missed-dose rules |
| Combined-hormone tablets | Whether an estrogen component is included and related cautions |
Storage and Travel Basics
Store tablets according to the package insert, typically at controlled room temperature and protected from excess heat and moisture. Bathrooms and car glove compartments often run humid or hot, which can degrade many medications over time. Keeping tablets in the original blister pack can also help protect them from light and makes it easier to verify lot numbers and expiration dates.
When traveling, carry medicines in hand luggage when possible and keep a copy of the prescription or pharmacy label available in case verification is needed. If a tablet looks discolored, crumbling, or unusually soft, it may have been exposed to moisture or heat and should be checked with a pharmacist before use.
Quick tip: Keep a current medication list with doses in a notes app.
For related life-stage planning, the overview in Menopause And Beyond Guide offers general context on hormonal transitions.
Side Effects and Safety
Side effects can vary by person and by whether the product includes estrogen. Commonly discussed effects across progestin-based therapies include headache, nausea, breast tenderness, acne, mood changes, and irregular bleeding or spotting, especially early in treatment. Medicines are supplied through licensed Canadian partner pharmacies. A prescriber may also consider how this therapy fits alongside conditions like migraines, depression, metabolic concerns, or prior pregnancy complications.
More serious symptoms warrant urgent clinical assessment, particularly when a combined estrogen-progestin product is used. Examples include chest pain, sudden shortness of breath, one-sided leg swelling, new severe headache, weakness on one side, or sudden vision changes—these can be signs of a clot-related event. Severe abdominal pain, yellowing of the skin or eyes, or heavy unexpected bleeding also deserve prompt evaluation. For hormone-related symptom context, PCOS Symptoms Guide may be a useful general resource.
Drug Interactions and Cautions
Hormone therapies can interact with medicines that change liver enzyme activity, which may alter hormone levels and reduce reliability for symptom control or contraception, depending on the product. Interactions are highly formulation-specific, so the medication list should be reviewed by a pharmacist and prescriber whenever a new drug is started or stopped.
Examples of interaction categories commonly discussed on hormone labels include:
- Enzyme-inducing anticonvulsants (seizure medicines)
- Rifamycin antibiotics used for tuberculosis
- Some HIV or hepatitis C regimens
- St. John’s wort (herbal supplement)
- Other hormone-containing therapies
Medical history also matters. Conditions affecting the liver, unexplained bleeding, or prior hormone-sensitive cancers may change whether a progestin-only approach is considered. If the product is used for contraception, backup methods and missed-dose rules should follow the specific insert.
Compare With Alternatives
Alternatives depend on the treatment goal: contraception, cycle regulation, or symptom management for conditions such as endometriosis. Some people are prescribed combined oral contraceptives that use different progestins, such as Yaz, while others may be prescribed non-contraceptive options that target ovarian hormone signaling, such as Orilissa. Each option has distinct contraindications, monitoring expectations, and side-effect profiles.
Another comparison point is whether the prescription is for a combined regimen that includes an estrogen component. For example, products combining estradiol valerate with Dienogest (often recognized internationally as Qlaira) may come with different pack designs and clot-related warnings than progestin-only approaches. Non-pill alternatives can include intrauterine devices (IUDs), barrier methods, or condition-specific therapies, and the right match is typically decided by clinical history and preferences.
Pricing and Access
Total costs depend on the exact product, strength, and days supplied, along with any required dispensing documentation. Requests are handled as cash-pay when insurance isn’t used. For people managing prescriptions without insurance, it can help to keep the prescriber’s contact details current, since verification steps may be needed before a partner pharmacy can dispense Dienogest.
On the site, the practical steps usually include submitting a prescription, confirming shipping details, and responding to any clarification requests from the pharmacy team. If available for a given product, updates may also appear on the Promotions page, though availability can change and is not guaranteed.
Authoritative Sources
Regulatory and reference sources can clarify how a specific formulation is labeled, what warnings apply, and how missed-dose rules are written. This matters because some labels discuss the ingredient as part of a combined product rather than as a stand-alone tablet. The links below are intended for cross-checking key safety language and for reviewing pharmacology background on Dienogest before discussing options with a licensed clinician.
- DailyMed listing for estradiol valerate/dienogest labeling
- NIH PubChem compound summary for dienogest
If a patient leaflet or label conflicts with general summaries, the leaflet instructions should be prioritized, and questions should be routed to the prescriber or dispensing pharmacist.
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This content is for informational purposes only and is not a substitute for professional medical advice.
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What is dienogest used for?
Dienogest is a synthetic progestin (a progesterone-like hormone). Depending on the specific product and country labeling, it may be prescribed as part of a plan to manage endometriosis-related symptoms or used within certain combined oral contraceptives that also contain an estrogen. The intended use, warnings, and dosing schedule can differ significantly between a progestin-only tablet and a combined-hormone pack. A clinician’s prescription and the product’s patient leaflet are the best sources for the exact indication for an individual prescription.
Is dienogest the same as a combined birth control pill?
Dienogest is an ingredient, not a single universal product type. Some prescriptions may involve a progestin-only formulation, while other products combine an estrogen with a progestin in one regimen. Combined oral contraceptives have additional contraindications and safety warnings compared with many progestin-only options, especially around clot risk and certain migraine histories. Because packaging and missed-dose instructions vary by formulation, it’s important to rely on the specific label and insert that comes with the dispensed medication.
What side effects are commonly reported with dienogest?
Side effects with progestin-based therapies can include headache, nausea, breast tenderness, acne, mood changes, and changes in bleeding patterns such as spotting or irregular bleeding. Some effects are more noticeable early in therapy and may change over time, but persistence varies by person. Risks and side effects can be different when the ingredient is used in a combined estrogen-progestin product compared with a progestin-only formulation. Any side effect that feels severe, sudden, or disruptive should be reviewed with a licensed clinician.
What symptoms should be treated as urgent while taking dienogest?
Urgent symptoms depend on the formulation, particularly if an estrogen is included, but certain signs should be treated seriously. These can include chest pain, sudden shortness of breath, one-sided leg swelling or pain, sudden severe headache, weakness or numbness on one side, or sudden vision changes, which may suggest a clot-related event. Severe abdominal pain, yellowing of the skin or eyes, fainting, or heavy unexpected bleeding also warrant prompt medical evaluation. Patients should follow the product’s warning section and clinician guidance.
What medications and supplements can interact with dienogest?
Hormone therapies can be affected by medicines that change how the liver metabolizes drugs. Some anticonvulsants, rifamycin antibiotics (used for tuberculosis), certain HIV or hepatitis C regimens, and the herbal supplement St. John’s wort are common examples discussed on hormone labels. These interactions may lower hormone levels or change side effects, and they can be especially important for contraceptive reliability with combined products. A complete, up-to-date medication list (including supplements) should be reviewed by the prescriber and pharmacist.
What should I ask my clinician before starting dienogest?
Useful topics include the exact goal of therapy, expected timeline for follow-up, and which warning symptoms matter most for the specific formulation. It also helps to discuss personal history that changes hormone safety decisions, such as migraines, smoking status, clot history, liver disease, abnormal bleeding, or prior hormone-sensitive cancers. Asking how missed doses should be handled for the exact product and pack format can prevent confusion later. If other medicines are taken regularly, interaction screening should be part of the conversation.
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