Please note: a valid prescription is required for all prescription medication.
Efavir® Tablets for HIV-1
Buy More, Save More: Get 20% off when you buy 3 or more of any one product using code LESS20 at checkout.
Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
Black Friday Bonus: Enjoy free standard shipping on all orders over $250.
Offer can be combined with the 20% “Buy More, Save More” discount. Enter each coupon code separately at checkout to claim your offers. Offer ends December 5, 2025.
Price range: $44.99 through $71.00
Secure Encrypted Payments
Efavir® is a prescription efavirenz tablet used with other HIV medicines. This page explains how the treatment works, who it may suit, and how to use it safely. We support US shipping from Canada, and you can review options even if paying without insurance.
What Efavir Is and How It Works
Efavirenz is a non-nucleoside reverse transcriptase inhibitor. It helps block the HIV-1 enzyme needed to make new virus. The treatment is taken with other antiretrovirals to lower viral load and support immune recovery. For background on the condition, see our HIV resource.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
An Efavir online purchase requires a valid prescription. You can use this page to compare alternatives, read label-aligned guidance, and plan storage for travel.
Who It’s For
This medicine is indicated as part of combination therapy for adults and certain adolescents with HIV-1. It is not used alone. People with a history of significant liver disease, serious psychiatric conditions, or known hypersensitivity to components should avoid it. Those who are pregnant or planning pregnancy should discuss risks and alternatives with a clinician. For general education on testing, visit Types Of HIV Tests or learn more at How Can You Get HIV.
Some patients consider affordability during therapy selection. If you explore Efavir pay out of pocket approaches, coordinate closely with your prescriber to keep your regimen consistent.
Dosage and Usage
Follow your prescriber’s directions and the official label. Adults often take a once-daily dose, typically at bedtime, to lessen central nervous system effects. Taking the tablet on an empty stomach may reduce side effects; high-fat meals can increase exposure. Swallow whole with water. Keep your other HIV medicines on the same schedule.
Dose adjustments, if any, are determined by your clinician. Pediatric dosing varies by weight and formulation. If you have liver impairment, your care team may monitor you more closely. When uncertain, defer to the official prescribing information.
The standard adult dose is commonly 600 mg once daily; this is general label information and not a substitute for medical advice.
Strengths and Forms
Tablets are commonly available in 200 mg and 600 mg strengths. Packaging and tablet appearance can vary by manufacturer and country. Availability may change over time.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember unless it is close to the next dose. If it is almost time for your next dose, skip the missed tablet. Do not double up. Keep a reminder system to support steady adherence. If vomiting occurs soon after dosing, contact your healthcare professional for guidance from the label.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from direct light. Keep the medicine in the original container with the label intact. Use child-resistant closures and store out of reach of children and pets. When traveling, carry your medication in hand luggage along with your prescription or pharmacy label. A simple list of your regimen can help at security checkpoints. If your plans involve climate extremes, use a protective case and avoid leaving the bottle in a hot car.
For broader therapy options within the class and beyond, you can browse our Antivirals catalog or filter by origin such as India.
Benefits
This therapy is part of a well-studied class used for combination regimens. Once-daily administration may fit routine schedules. Taking it at bedtime can help some people manage dizziness or vivid dreams. Combined with other antiretrovirals, the treatment can help reduce viral load and support immune health when taken as prescribed.
Side Effects and Safety
- Dizziness or drowsiness
- Trouble sleeping or unusual dreams
- Headache or fatigue
- Nausea or stomach upset
- Rash or itching
Serious risks can include severe rash, liver problems, mood changes, depression, suicidal thoughts, seizures, and heart rhythm issues. Seek urgent care for severe skin reactions, signs of liver injury, or new psychiatric symptoms. Hypersensitivity reactions require discontinuation and medical evaluation. Use caution with alcohol or other sedatives. Discuss plans for pregnancy, contraception, and breastfeeding with your prescriber.
Drug Interactions and Cautions
Efavirenz affects CYP enzymes and has many interactions. Some benzodiazepines, certain antiarrhythmics, ergot derivatives, and pimozide are contraindicated. St. John’s wort can reduce levels and should be avoided. Interactions may occur with rifampin or rifabutin, some antifungals, anticonvulsants, methadone, and warfarin. Hormonal contraceptives may be less effective; consider barrier methods. Certain hepatitis C regimens and boosted protease inhibitors have complex interactions. Share your full medication and supplement list with your clinician and pharmacist.
What to Expect Over Time
With consistent use in a complete regimen, viral load may decline and immune markers may improve. Some central nervous system effects can appear early and often lessen with time. Keep a regular dosing routine, maintain clinic follow-ups, and complete recommended lab monitoring. If you and your clinician decide to change therapy, follow a coordinated plan to prevent resistance. Some choose an Efavir self pay route when navigating coverage gaps; factor clinical needs first.
Compare With Alternatives
Other options in the same class include doravirine and etravirine. Depending on your regimen needs and tolerability, your prescriber may consider Pifeltro or the fixed-dose combination Delstrigo. For a broader view of evolving regimens, see Evolving Landscape.
Pricing and Access
You can view current Efavir price on the product page and compare formats. Many patients evaluate total regimen costs across multiple agents. We offer transparent listings with US delivery from Canada for eligible prescriptions. If you are exploring Efavir Canadian pricing, check the listing details and discuss any questions with our support team.
For helpful offers, visit our Promotions page. Checkout uses encrypted checkout for data protection. Coverage varies by plan; if paying cash, you can compare options and place an order once your prescription is received.
Availability and Substitutions
Supply can vary by manufacturer and lot. If an item is unavailable, your prescriber may recommend a clinically appropriate alternative in the same class or a different class. Some patients prefer Efavir from Canada due to selection and pricing differences. You can also review related agents within Antivirals or explore condition topics like Vaccine To Prevent HIV.
Patient Suitability and Cost-Saving Tips
Good candidates can take a once-daily NNRTI as part of a fully suppressive regimen and can maintain adherence. People with severe psychiatric histories, significant liver disease, or serious skin reactions to similar medicines may need a different option. If contraception is needed, add a reliable barrier method.
- Multi-month fills: ask your prescriber about longer supplies
- Set reminders: phone alarms or pillboxes support adherence
- Coordinate labs: align refills with clinic visits
- Travel-ready: keep a spare small supply in carry-on
If you rely on Efavir cash price, consider consolidating refills across your regimen, reviewing eligible generics, and comparing combination products. For community information and screening reminders, see HIV Testing Day.
Questions to Ask Your Clinician
- Is this NNRTI a good fit for my regimen and history?
- How should I manage early dizziness or sleep changes?
- Which interactions are most important with my current medicines?
- What contraceptive methods should I use while on therapy?
- How often should I have liver tests and other monitoring?
- What signs or symptoms mean I should contact the clinic?
Authoritative Sources
FDA DailyMedFDA Drug DatabaseHealth Canada DPD
Ready to proceed? You can place your order with prompt, express shipping that Ships from Canada to US after we receive and verify your prescription. This information is educational and not a substitute for professional medical advice.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Why should Efavir be taken at bedtime?
Taking it at bedtime helps reduce dizziness and vivid dreams during waking hours.
Can Efavir be taken with food?
It should be taken on an empty stomach, as food increases drug levels and may worsen side effects.
What if I miss a dose of Efavir?
Take the missed dose as soon as you remember. If your next dose is near, skip the missed dose.
Does Efavir cure HIV?
No, it helps control HIV but is not a cure. Consistent use with other antiretrovirals is essential.
Are mood changes with Efavir permanent?
Mood changes and vivid dreams usually lessen over time. Report persistent symptoms to your doctor.
Can I take this medicine with food or at bedtime?
Label guidance suggests taking the tablet on an empty stomach, preferably at bedtime, to reduce central nervous system effects like dizziness or vivid dreams. A high-fat meal may increase exposure and side effects. Swallow the tablet whole with water. Keep the rest of your HIV regimen on a consistent schedule. If you have trouble sleeping or daytime drowsiness, tell your healthcare professional so they can review options within your overall plan.
What common side effects should I watch for early on?
Many people notice dizziness, drowsiness, trouble sleeping, or unusual dreams. Headache, tiredness, nausea, and rash can also occur. These effects may improve after the first weeks as your body adapts. Contact your prescriber if symptoms are severe, persistent, or interfere with daily activities. Seek urgent care for serious skin reactions, signs of liver trouble, new mood changes, or thoughts of self-harm.
Does it interact with birth control or other medicines?
Efavirenz can lower levels of some hormonal contraceptives, so a barrier method is recommended. The medicine also interacts with many drugs and supplements through liver enzymes. St. John’s wort should be avoided. Certain sedatives, antiarrhythmics, antifungals, anticonvulsants, and hepatitis C regimens have important interactions. Share all medicines and supplements with your clinician and pharmacist to help prevent issues.
What if I miss a dose or vomit after taking it?
If you miss a dose, take it when you remember unless it’s close to the next dose. Skip the missed dose if you’re near the next scheduled time, and never double up. If you vomit soon after taking your tablet, contact your healthcare professional for label-based advice. Keeping reminders and a simple daily routine can help prevent missed doses and support long-term adherence.
Is this treatment safe during pregnancy or breastfeeding?
Risks and benefits should be discussed before conception and during pregnancy. Your clinician may recommend a different regimen depending on timing and clinical factors. Because the medicine passes into breast milk and transmission risks are complex, breastfeeding guidance varies by region. Follow your prescriber’s advice and local guidelines when planning for pregnancy or infant feeding.
Can I drive or operate machinery while on therapy?
Dizziness, drowsiness, and concentration changes can occur, especially when starting therapy. Until you know how you respond, avoid driving or operating machinery. Alcohol and other sedatives may worsen these effects. If symptoms persist or affect safety, contact your clinician. Taking the tablet at bedtime and on an empty stomach may help lessen daytime effects for some people.
How is this medicine stored at home and during travel?
Store tablets at room temperature, in a dry place away from light, and keep them in the original, labeled container. Use child-resistant caps and store out of reach of children and pets. When traveling, pack your supply in carry-on luggage with your prescription or pharmacy label. Avoid leaving the medication in a hot car or near moisture, and carry a small backup supply when possible.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
How to book an appointment
- 1Create Begin by completing a profile or log into your existing account. This step ensures we have the necessary information to provide you with a service that's tailored to your needs. account and start earning.
- 2Scheduling an appointment with our online booking system is easy. Pick a day and time that suits you. You’ll receive an immediate confirmation, without the wait.
- 3Discuss your concerns and symptoms and receive a thorough diagnosis from one of our licensed doctors during a confidential video appointment.
- 4If you've been prescribed medication, your Rx is sent directly to one of our licensed pharmacies and delivered right to your door.
Get Started
To book an online doctor appointment, register for an account or login. After doing so, you can book your visit on this page.


