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Jardiance (empagliflozin) Tablets
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Empagliflozin is an SGLT2 inhibitor (kidney glucose blocker) taken by mouth. It is prescribed for adults with type 2 diabetes and, in some cases, for heart-related conditions. This page explains practical basics for safe use and handling.
Jardiance is the brand name for empagliflozin tablets. The information below summarizes common reasons it is prescribed and how it works. It also reviews typical schedules and key cautions from labeling. Use the links to browse condition hubs and read longer guides.
What Jardiance Is and How It Works
This medicine belongs to the SGLT2 inhibitor class, which lowers blood glucose by helping the kidneys remove some glucose into the urine. Ships from Canada to US through a prescription referral model, and options may help people without insurance use cash-pay access. The same mechanism can also cause mild fluid loss, so clinicians often consider hydration and blood pressure alongside glucose goals.
By increasing urinary glucose excretion, the treatment can reduce fasting and after-meal glucose levels. The shift in kidney handling of sodium and water may also affect circulation, which is one reason this drug class is studied in heart conditions. Effects vary by individual factors, including kidney function and other medicines. For broader background on diabetes and cardiovascular risk, browse Type 2 Diabetes Articles and the guide Diabetes And Heart Attacks.
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Who It’s For
In many settings, this therapy is prescribed to improve blood sugar control in adults with Type 2 Diabetes, alongside nutrition and activity plans. Depending on local labeling and a clinician’s assessment, it may also be used for adults with Heart Failure to support heart-related outcomes. Treatment selection often depends on kidney function, cardiovascular history, and whether other glucose-lowering medicines are used.
Jardiance is not used for type 1 diabetes and should not be started to treat diabetic ketoacidosis (a serious acid buildup). It is contraindicated in people with a known serious allergy to empagliflozin and in patients on dialysis. For glycemic control, use may be limited when kidney function is significantly reduced, because the glucose-lowering effect depends on filtration through the kidneys. A prescriber can clarify whether the intended use matches current labeling in the dispensing jurisdiction.
Why it matters: The right indication helps balance benefits with risks like dehydration or infections.
Dosage and Usage
This medication is taken once daily by mouth, typically at the same time each day. Jardiance is commonly started at 10 mg once daily, and some patients may have the dose increased to 25 mg once daily if additional glucose lowering is needed and tolerated. Tablets are usually swallowed whole with water and can be taken with or without food. If a dose is missed, labeling generally advises taking it when remembered unless it is close to the next dose; double-dosing is not recommended.
Clinicians may adjust the overall diabetes regimen to reduce low blood sugar risk when this drug is combined with insulin or a sulfonylurea. In some cases, a prescriber may recommend holding SGLT2 inhibitors before major surgery or prolonged fasting to reduce ketoacidosis risk. Because kidney function influences both safety and effectiveness, baseline and periodic renal labs are commonly part of routine follow-up. For condition-focused product browsing, see the Diabetes Care category. For related discussion of heart failure therapy planning, the article Metformin And Heart Failure offers additional context.
Monitoring basics
Ongoing monitoring typically focuses on kidney function, blood pressure, and glucose patterns. Some people notice increased urination, which can affect hydration and dizziness risk, especially in hot weather or when also taking diuretics. Clinicians may ask about symptoms that could suggest ketoacidosis (nausea, vomiting, abdominal pain, unusual fatigue, or rapid breathing) even if glucose is not very high. Reporting genital irritation or urinary symptoms early matters, since infections can progress. If home glucose monitoring is used, the prescriber can interpret trends and decide whether other medicines need adjustment.
Strengths and Forms
This product is supplied as oral tablets in two strengths: 10 mg and 25 mg of empagliflozin. Many people start with the lower strength, then move to the higher strength if appropriate. When discussing fills, it can help to confirm the exact strength and quantity on the prescription so the dispensing pharmacy can match what the prescriber intended.
Jardiance 10 mg tablets and the 25 mg strength are both film-coated tablets; packaging (bottle vs blister) can vary by manufacturer and dispensing source. In clinical terms, the active ingredient is empagliflozin, and listings may also describe it as empagliflozin tablets, empagliflozin 10 mg tablet, or empagliflozin 25 mg tab. Availability of a generic of Jardiance (empagliflozin brands or empagliflozin tablets) depends on country-specific approvals and market timing, so options may differ between jurisdictions.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from direct light and moisture. Keep the medicine in its original container or a properly labeled pharmacy package, and store it out of reach of children and pets. Avoid storing doses in places that can get hot or humid, such as cars, bathrooms, or near kitchen sinks. If tablets appear damaged or unusually discolored, ask a pharmacist before use.
For travel, it is usually easiest to keep tablets in a carry-on bag to avoid temperature swings. Carry a copy of the prescription or pharmacy label for identification, especially when crossing borders. If time zones change, many people keep the once-daily schedule anchored to a consistent morning routine; a prescriber can clarify what to do if timing shifts lead to missed doses. If nausea, vomiting, or reduced intake occurs during travel, clinicians may advise temporary changes to diabetes medicines to lower dehydration and ketoacidosis risk.
Quick tip: Keep a photo of the label for reference if packaging is lost.
Side Effects and Safety
Common side effects with SGLT2 inhibitors include increased urination, thirst, and genital yeast infections (fungal irritation). Urinary tract infections can occur, and some people notice mild dizziness, especially when standing quickly. Because the medicine increases fluid loss, the risk of low blood pressure can be higher in older adults, people on diuretics, or those with reduced kidney function. Routine follow-up often includes a review of hydration status and kidney labs.
Jardiance can rarely be associated with serious problems such as ketoacidosis, severe urinary infection (including kidney infection), acute kidney injury, or necrotizing fasciitis of the perineum (a dangerous soft-tissue infection). Seek urgent care for severe weakness, confusion, fainting, rapid breathing, severe genital pain or swelling, or signs of an allergic reaction. Low blood sugar is more likely when combined with insulin or sulfonylureas. If more context on cardiovascular risk factors is helpful, browse Cardiovascular Articles.
Prescriptions are confirmed with prescribers before the medicine is dispensed.
Drug Interactions and Cautions
Drug interactions are usually managed by reviewing the full medication list, including over-the-counter products and supplements. Combining this therapy with insulin or insulin secretagogues (such as sulfonylureas) can increase the chance of hypoglycemia, so clinicians may adjust those agents. Diuretics can add to fluid loss and may increase dizziness or low blood pressure risk. Alcohol use, low-carbohydrate diets, or prolonged fasting can also raise ketoacidosis risk in susceptible patients.
Kidney function and blood pressure medicines often intersect with diabetes regimens, so prescribers may monitor labs and vital signs after changes. In some cases, monitoring may be considered when used with digoxin, since small changes in levels have been reported with SGLT2 inhibitors. Always report new symptoms such as reduced urination, extreme thirst, or persistent vomiting. For browsing related heart and vascular medicines by category, visit the Cardiovascular Category hub.
Compare With Alternatives
Several other medicines treat type 2 diabetes and may also be used in heart failure. Within the same SGLT2 inhibitor class, dapagliflozin is a common alternative; across other classes, options include metformin, DPP-4 inhibitors, GLP-1 receptor agonists, and sulfonylureas. Each class differs in side effects, monitoring needs, and how it fits alongside kidney function or heart conditions. For a deeper look at class-level heart failure research, see SGLT2 Inhibitors In Heart Failure.
If a prescriber is considering a switch within the class, related product listings include Forxiga Tablets and Dapagliflozin Tablets. The article Exploring Dapagliflozin Uses provides additional discussion points to bring to a clinical visit. Any change in therapy should be guided by the prescriber, especially when insulin or diuretics are part of the regimen.
Pricing and Access
Out-of-pocket costs for Jardiance can vary by strength, quantity, and dispensing source, and coverage rules differ across plans. Some people compare cash-pay pricing with what they would pay through private insurance or public programs, including Medicare, when eligible. US shipping from Canada is part of the platform’s access model, but a valid prescription is still required and reviewed before dispensing.
Cash-pay access is available, including options for people without insurance. If a clinician writes for empagliflozin 10 mg or 25 mg, having the current medication list and recent kidney labs available can help reduce delays during verification. The Promotions Page may list site-wide programs that apply to eligible prescriptions, though availability can change.
Authoritative Sources
For the most accurate prescribing details, always rely on the current product label and the clinician’s directions on the prescription. Official sources are also useful when reviewing contraindications, kidney thresholds, and perioperative guidance for SGLT2 inhibitors. When reading online summaries, check that the information matches the jurisdiction where the medication will be dispensed, since approved indications and warnings can differ.
The references below are good starting points for label-based information and patient-facing summaries. If anything conflicts with a prescription label or a clinician’s plan, the prescriber’s instructions should take priority.
- For U.S. labeling and approval history, see Drugs@FDA Database.
- For patient-friendly drug information, review MedlinePlus Empagliflozin.
- For Canadian product listings and monographs, consult Health Canada Drug Product Database.
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This content is for informational purposes only and is not a substitute for professional medical advice.
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What is Jardiance used for?
Jardiance (empagliflozin) is commonly prescribed to improve blood sugar control in adults with type 2 diabetes, alongside diet and physical activity. Depending on the product labeling in the dispensing jurisdiction and a clinician’s judgment, it may also be prescribed for certain heart-related indications, such as heart failure. It is not used for type 1 diabetes and is not a treatment for diabetic ketoacidosis. A prescriber can confirm whether the reason for use matches current approved indications and individual risk factors.
How does empagliflozin lower blood sugar?
Empagliflozin is a sodium-glucose cotransporter-2 (SGLT2) inhibitor, sometimes described as a “kidney glucose blocker.” It works by reducing the kidneys’ reabsorption of filtered glucose, which increases glucose elimination in the urine. As a result, blood glucose levels can fall. Because this mechanism also leads to additional urine output, some people notice more frequent urination or thirst. The extent of glucose lowering depends partly on kidney function, so clinicians often monitor renal labs during therapy.
What are common side effects of Jardiance?
Common effects include increased urination and thirst, which relate to the medicine’s mechanism. Genital yeast infections and urinary tract infections can also occur, and the risk may be higher in people with prior infection history. Some people experience dizziness, especially when standing, which can be related to volume depletion (reduced body fluid). Low blood sugar is more likely when the drug is taken with insulin or sulfonylureas. If symptoms are new, persistent, or severe, it is important to contact a healthcare professional.
Can Jardiance cause ketoacidosis even if sugar isn’t very high?
Yes. SGLT2 inhibitors, including empagliflozin, have been associated with ketoacidosis, and it can sometimes occur with blood glucose that is not markedly elevated. Warning symptoms can include nausea, vomiting, abdominal pain, unusual fatigue, rapid breathing, or confusion. Risk can increase during prolonged fasting, significant illness, heavy alcohol intake, or around major surgery. Because ketoacidosis is serious, people should seek urgent medical evaluation if these symptoms occur and tell clinicians they are taking an SGLT2 inhibitor.
What monitoring is usually recommended while taking empagliflozin?
Monitoring commonly includes kidney function tests (such as serum creatinine/eGFR) before starting and periodically after, because renal function affects both safety and effectiveness. Clinicians may also monitor blood pressure, since the medication can increase urine output and contribute to lower blood pressure in some individuals. Glucose monitoring plans vary based on the overall regimen; those using insulin or sulfonylureas may monitor more closely for hypoglycemia. Patients should also report signs of urinary or genital infections early so treatment can begin promptly.
What should I ask my clinician before starting Jardiance?
Helpful questions include: whether the medication is being used for diabetes control, a heart-related indication, or both; what kidney function thresholds apply; and how often labs should be checked. It is also worth discussing sick-day plans, including what to do during vomiting, dehydration, fasting, or before surgery. Ask how to recognize symptoms of ketoacidosis and serious infections, and whether other diabetes medicines (especially insulin or sulfonylureas) should be adjusted to reduce hypoglycemia risk. Bring an updated medication and supplement list to the visit.
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