Kazano® Tablets for Type 2 Diabetes

Kazano combines alogliptin and metformin in one tablet for adults with type 2 diabetes. It supports blood sugar control alongside diet and exercise. If you are comparing options for US delivery from Canada, this page explains uses, dosing, safety, and how you can order, even if you are paying Kazano without insurance.

What Kazano Is and How It Works

Kazano® contains two medicines that work in complementary ways. Alogliptin is a DPP-4 inhibitor that helps your body increase insulin release after meals and lowers glucagon. Metformin is a biguanide that reduces glucose made by the liver and improves how your body uses insulin. Together, the combination can help improve fasting and post-meal glucose when used with diet and exercise.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine is taken by mouth with food. It is not insulin. The combination may be considered when metformin alone is not enough, or to replace separate alogliptin and metformin tablets under a clinician’s guidance.

As a class, DPP-4 inhibitors generally have a low risk of low blood sugar, but the risk can increase if used with insulin or sulfonylureas. Metformin may cause gastrointestinal effects at the start; taking with meals can help.

Who It’s For

The treatment is indicated to improve glycemic control in adults with type 2 diabetes, as an adjunct to diet and exercise. It is not for type 1 diabetes or for treating diabetic ketoacidosis. It should not be used in patients with severe kidney problems, metabolic acidosis, or in settings that raise the risk of lactic acidosis.

Tell your clinician about kidney or liver disease, heart failure, alcohol use, pancreatitis history, or a plan for iodinated contrast imaging. Discuss pregnancy or breastfeeding plans. For broader background on the condition, see our resource on Type 2 Diabetes.

Dosage and Usage

Standard directions follow the official label. The tablet is typically taken twice daily with meals. Your prescriber chooses a strength based on your current regimen and kidney function. Do not crush or split unless your clinician advises. Swallow with water, ideally at the same times each day to support routine.

If you are switching from separate components, your prescriber may match equivalent daily doses while considering tolerability. If gastrointestinal effects occur, taking the dose with the largest meal may help. Keep regular follow-up to review glucose logs and periodic labs.

Strengths and Forms

The combination is supplied as film-coated oral tablets in multiple strengths. Availability can vary by partner pharmacy and manufacturer.

• Alogliptin metformin 12.5/1000 mg tablets
• Other common presentations include 12.5 mg/500 mg and 12.5 mg/850 mg

Your prescriber will select the strength suited to your treatment plan.

Missed Dose and Timing

If you miss a dose, take it when remembered unless it is close to the next scheduled time. If it is almost time for your next dose, skip the missed dose and resume your normal schedule. Do not take two doses at once.

Consistency matters. Pair doses with daily routines such as breakfast and dinner to help adherence. A pill organizer and phone reminders can be helpful.

Storage and Travel Basics

Store the tablets at room temperature and protect them from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Do not store in the bathroom. Use the original labeled container during travel.

When traveling, pack enough tablets plus a small buffer, and carry a copy of your prescription. Keep medicine in your carry-on to avoid temperature extremes. If your trip crosses time zones, maintain roughly the same spacing between doses and consult the label or your clinician with timing questions.

For related supplies and tools, explore our Diabetes Care section.

Benefits

This medicine can simplify therapy by combining two proven agents in one pill. It may reduce pill burden versus taking components separately. The DPP-4 inhibitor supports post-meal control, while metformin supports fasting levels and overall insulin sensitivity. Many people appreciate a familiar metformin backbone with an add-on from a different class.

Combining mechanisms can support A1C reduction when used with lifestyle measures. Once-daily or twice-daily schedules with meals can fit into daily routines. For an overview of treatment classes, see our Diabetes Drugs List and this primer on Types Of Insulin.

Side Effects and Safety

• Stomach upset, nausea, or diarrhea
• Headache or dizziness
• Upper respiratory symptoms or nasopharyngitis
• Back pain or joint aches
• Loss of appetite or mild taste change

Serious risks are uncommon but can occur. Metformin has a rare risk of lactic acidosis that is higher with kidney impairment, dehydration, or heavy alcohol use. DPP-4 inhibitors have reported rare pancreatitis and severe allergic reactions. Hypoglycemia can occur, especially if used with insulin or sulfonylureas. Vitamin B12 levels can decline with long-term metformin use. Seek urgent care for severe abdominal pain, rash or swelling, trouble breathing, or signs of profound weakness.

Drug Interactions and Cautions

Tell your clinician about all medicines and supplements. Iodinated contrast for imaging may require temporarily withholding metformin. Excessive alcohol increases lactic acidosis risk. Some cationic drugs that compete for renal tubular secretion can affect metformin levels. Review any insulin or sulfonylurea therapy since the combination can increase low blood sugar risk with those agents.

Report any pancreatitis history, gallstones, or high triglycerides. Monitor kidney function as advised. If you develop illness with dehydration, ask your clinician about temporarily pausing therapy. For condition-specific education, our guide on Insulin Resistance may help your discussions.

What to Expect Over Time

With regular use and lifestyle changes, many people see smoother day-to-day glucose readings. Effects can vary. Your clinician may review self-monitoring logs and periodic A1C to assess progress. If tolerated, a stable routine with meals often supports adherence.

Expect initial digestive symptoms to improve for many as the body adjusts. Keep hydrated, and take doses with food. If readings trend low, especially when using insulin or sulfonylureas, contact your clinician. Plan routine refills so you do not run out, and use reminders to stay on schedule.

Compare With Alternatives

Other prescription options may suit different needs. A DPP-4 inhibitor alone such as Sitagliptin may be used with metformin when a fixed-dose combination is not preferred. An SGLT2-metformin combination like Xigduo 60 Tablets may be considered when kidney function and clinical goals align. Discuss choices with your prescriber.

Pricing and Access

Border Free Health lists current Kazano price information so you can compare options. We source through licensed partners with Canadian pricing and US shipping from Canada. You can also Buy alogliptin metformin through our secure checkout. We display clear pricing and show typical cash-pay considerations. For periodic offers, see our Promotions. Payment is handled via encrypted checkout.

If you are browsing country-of-origin details, visit Canada. For broader diabetes essentials, explore Diabetes Care.

Availability and Substitutions

Supply can vary by strength and manufacturer. If a particular tablet is unavailable, a prescriber may recommend a therapeutically appropriate alternative or separate components. We do not quote restock dates. Your clinician will decide if a substitution is medically suitable.

Patient Suitability and Cost-Saving Tips

Good candidates are adults with type 2 diabetes who can take metformin and a DPP-4 inhibitor and who benefit from a combined tablet. It is not suited for type 1 diabetes, people with significant kidney disease, metabolic acidosis, or those with a history of serious hypersensitivity to components.

• Refill rhythm: set reminders before you run out
• Multi-month fills: consider a Kazano 90 day supply if appropriate
• Travel ready: carry extra tablets and your prescription
• Discuss options: ask about alternatives if costs or tolerance are issues
• Stay consistent: take with meals to support tolerability

Building a steady routine can reduce missed doses. For healthy living support, see our article on Type 2 Reversal Facts and tips for awareness in National Diabetes Month 2025.

Questions to Ask Your Clinician

• Is this combination appropriate with my kidney function?
• How should I time doses with meals and other medicines?
• What signs suggest lactic acidosis or pancreatitis?
• Could my hypoglycemia risk change with current therapies?
• How often should we check A1C and B12?
• What are my alternatives if I do not tolerate the tablets?
• Should I pause doses before contrast imaging or procedures?

Authoritative Sources

Order Kazano online at Border Free Health. Enjoy prompt, express shipping with clear pricing and careful handling for your order.

Disclaimer: This page is educational and not a substitute for professional medical advice. Always follow your prescriber’s directions and the approved label.