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Lixiana
Price range: $139.99 through $145.99
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Lixiana (edoxaban) is an oral anticoagulant used to prevent and treat blood clots, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in patients with atrial fibrillation. It works by inhibiting factor Xa in the coagulation pathway.
Benefits:
- Reduces risk of stroke and systemic embolism
- No need for routine INR monitoring
- Fixed once-daily dosing
- Lower risk of major bleeding compared to warfarin
Dosage:
- Standard dose: 60 mg once daily
- Reduced dose: 30 mg daily in patients with renal impairment or low body weight
- Start after at least 5 days of parenteral anticoagulation in DVT/PE
- Adjust dose as per renal function and indication
Warnings and Precautions:
- Increased risk of bleeding
- Use caution in patients with impaired kidney function
- Not recommended with potent P-gp inhibitors
- Discontinue before major surgery
Usage Instructions:
- Take once daily with or without food
- Swallow the tablet whole with water
- Do not skip doses
- Follow the physician’s advice on use with other medications
Storage Information:
- Store below 30°C
- Keep in the original blister pack
- Protect from moisture and light
- Keep out of reach of children
Common Side Effects:
- Easy bruising
- Nosebleeds
- Gastrointestinal discomfort
- Anemia
- Rash
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- United States (all contiguous states**)
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Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
What is Lixiana used for?
Lixiana (edoxaban) is an oral anticoagulant used to prevent stroke and systemic embolism in patients with non-valvular atrial fibrillation. It is also used for the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE).
How does Lixiana work?
Lixiana is a direct Factor Xa inhibitor, meaning it blocks a key enzyme in the coagulation cascade. This action helps prevent the formation of blood clots without requiring routine blood monitoring like older anticoagulants such as warfarin.
Can Lixiana cause bleeding?
Yes, as with all anticoagulants, bleeding is the most significant risk. Patients should report any unusual bruising, blood in urine or stool, or prolonged bleeding, and should avoid activities that increase injury risk.
How should Lixiana be taken?
Lixiana is typically taken once daily with or without food. It’s important to take it at the same time each day to maintain consistent blood levels and ensure optimal protection against clot formation.
Is routine blood monitoring needed with Lixiana?
Unlike warfarin, Lixiana does not require regular INR monitoring. However, kidney function should be periodically checked to ensure the medication is being cleared properly, especially in elderly patients.
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