Neupro® Transdermal Patch for Parkinson's Disease and RLS

The Neupro transdermal patch is a prescription dopamine agonist for Parkinson’s disease and moderate-to-severe Restless Legs Syndrome. It delivers rotigotine through the skin for continuous symptom control. This page explains how it works, who it may suit, safety basics, and how you can order without insurance.

What Neupro Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing. Neupro® contains rotigotine, a dopamine agonist that stimulates dopamine receptors in the brain. It provides steady 24-hour exposure via a once-daily patch. This helps manage motor symptoms of Parkinson’s disease and the uncomfortable urges and sensations of Restless Legs Syndrome. With US delivery from Canada, you can access this therapy while working with your prescriber.

The medicine bypasses the digestive tract, so food does not affect absorption. The adhesive matrix slowly releases rotigotine across the skin. As a rotigotine transdermal system, it supports round-the-clock control, including early morning hours when symptoms can be more noticeable.

Who It’s For

This treatment is approved for adults with Parkinson’s disease and for adults with moderate-to-severe primary Restless Legs Syndrome. It may be used alone or with other antiparkinson agents under clinician guidance. For an overview of Parkinson’s symptoms, see our category page on Parkinsons Disease. For restless legs, visit Restless Legs Syndrome.

Do not use if you have a known allergy to rotigotine or patch components, or if you have repeated or severe skin reactions to adhesives. People with a history of hallucinations, impulse-control issues, low blood pressure, severe cardiovascular disease, or significant mental health conditions should discuss risks with a prescriber first. If pregnant or breastfeeding, ask a healthcare professional about potential risks and benefits.

Some patients specifically seek a patch option for adherence or swallowing concerns. For RLS, an exact phrase often used is Neupro patch for RLS, but decisions should always be individualized with your prescriber.

Dosage and Usage

Apply one patch to clean, dry, hairless skin once daily. Choose one of these areas: abdomen, hip, thigh, flank, shoulder, or upper arm. Press firmly for 30 seconds to ensure full contact, especially around the edges. Wash hands after applying. Rotate sites daily, leaving at least 14 days before reusing the same area.

Do not cut a patch. Avoid external heat sources on or near the patch, such as heating pads, saunas, hot tubs, or direct sunlight on the patch area. Heat can increase absorption and raise the chance of side effects. If the edges lift, smooth them down; if a patch falls off, apply a new one to a different site and continue your usual schedule the next day.

Your prescriber will determine the starting dose and titration plan based on your condition and response. If you switch from another dopamine agonist, follow medical guidance closely to reduce withdrawal or additive effects. For broader context on neurologic therapies, see our Neurology category.

Strengths and Forms

The patch is available in multiple strengths (mg per 24 hours): 1, 2, 3, 4, 6, and 8 mg/24 h. Each is a transdermal system intended for once-daily use. Availability can vary by market and timing. Your prescriber will match the strength to your needs, and may adjust over time based on response and tolerability.

Missed Dose and Timing

If you forget to apply a patch, put one on as soon as you remember. Replace it at your usual time the next day. If a patch loosens or falls off, apply a new one to a different site and keep your standard replacement time. Avoid doubling patches to make up for a missed application unless your prescriber has explicitly instructed that schedule.

Storage and Travel Basics

Store patches in their original pouches until use, and protect from moisture. Keep at typical room conditions away from direct heat sources. Do not freeze. When traveling, pack enough patches for the trip and a few extras in case of damage. Keep them in carry-on baggage with a copy of your prescription. Dispose of used patches by folding them in half with the sticky sides together and placing them in a safe container out of reach of children and pets.

Security checkpoints and routine trips should not affect the patch. Remove the patch before an MRI or cardioversion procedure because some patches contain metal layers that can heat during these studies. Our checkout is encrypted, and temperature-controlled handling when required is used across our network.

Benefits

This class provides continuous drug exposure over 24 hours, which can help with fluctuations that occur between oral doses. Many patients appreciate the once-daily routine. A patch can be helpful if swallowing pills is difficult or if morning symptoms are bothersome. Continuous delivery may also reduce peaks and troughs that can occur with some oral regimens, though responses vary.

Side Effects and Safety

Common effects may include nausea, vomiting, dizziness, drowsiness, headache, insomnia, application-site redness or itching, and swelling of the legs or ankles. Skin reactions at the patch site are usually mild to moderate. If irritation persists, worsens, or spreads, contact your prescriber.

• Daytime sleepiness
• Orthostatic hypotension or fainting
• Hallucinations or confusion
• Impulse-control problems
• Worsening dyskinesia with levodopa
• Allergic skin reactions

Rare but serious risks can include sudden sleep episodes, severe low blood pressure, hallucinations with behavioral changes, or compulsive behaviors such as gambling or shopping. Visual changes, severe rash, or swelling of the face or throat require urgent care. The risk of hypoglycemia is not a class effect here, but caution is needed if you take multiple sedating medicines.

If you use cholinesterase inhibitors for cognition, such as Exelon Patch 30 Units, or MAO-B inhibitors like Selegiline, your prescriber may monitor for additive side effects like nausea or dizziness.

Drug Interactions and Cautions

Tell your clinician about all medicines and supplements. Dopamine antagonists, including many antipsychotics, may reduce the effect of this therapy. Alcohol or sedatives can increase drowsiness. Antihypertensives may enhance low blood pressure, especially when standing. Combining with levodopa may increase dyskinesia; clinicians often adjust regimens over time.

Impulse-control issues may occur with dopamine agonists; report new urges or behaviors. People with severe cardiovascular disease or a history of psychosis require careful assessment. For a general primer on interaction risks, see our article Drug Interactions. Other dopamine-related therapies, such as Cabergoline, can have overlapping cautions and should be coordinated by a prescriber.

What to Expect Over Time

Most people start at a low dose and may adjust gradually under medical guidance. Skin reactions, if they occur, often improve with careful rotation and site care. As dosing is optimized, many patients notice steadier control across the day and night. If side effects limit use, your clinician may pause titration or consider alternatives. Keep a simple symptom and patch log; it can help your prescriber fine-tune therapy.

Compare With Alternatives

Other approved options may be considered depending on symptoms and response. MAO-B inhibition is a common approach; see Azilect for a once-daily oral option. Combination dopaminergic therapy remains a mainstay; Levodopa Carbidopa is frequently used as part of a tailored plan. Your clinician can advise how these might compare and whether a patch formulation fits your daily routine.

Pricing and Access

Many patients look for Canadian pricing with reliable US fulfilment. If you are comparing the Rotigotine patch price, review our current listings and talk with your prescriber about suitability. We highlight typical self-pay ranges and pharmacy-sourced options when available. For coupons or seasonal offers, visit our Promotions page.

We also note Neupro patch Canadian pricing when stock permits. Ships from Canada to US with a valid prescription. You can browse neurology items and condition pages to understand choices and talk through the plan with your clinician. For research updates in related fields, explore Alzheimers Care.

Availability and Substitutions

Supply can vary by strength and pack size. We post real-time status on product pages and will ask for your prescription details for verification. If you are checking Neupro patch availability and it is out of stock, your prescriber may recommend an alternative class or a different delivery form. Condition-specific goals, side effects, and daily routines help guide the choice.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults who prefer a once-daily patch, need around-the-clock symptom coverage, or have difficulty with oral dosing. It may not be ideal for those with significant adhesive allergies, uncontrolled hallucinations, or recurrent severe skin reactions. If you have orthostatic hypotension or are at risk for falling asleep during daytime activities, use caution and discuss monitoring plans with your clinician.

To manage costs, consider multi-month fills when your prescriber deems the dose stable. Set reminders for patch changes and reorder dates to avoid gaps. Compare options across our Neurology category, and review country-of-origin details on pages such as Canada. If you also manage cognitive symptoms in Parkinson’s disease, talk with your clinician about options like Exelon Patch 30 Units for separate indications.

Questions to Ask Your Clinician

• Starting plan: which strength and how often to review
• Skin care: rotation tips and managing irritation
• Safety: driving, operating machinery, or daytime sleepiness
• Interactions: antipsychotics, sedatives, or blood pressure medicines
• Procedures: removing the patch before MRI or cardioversion
• Alternatives: when to consider oral dopaminergic options

Authoritative Sources

FDA DailyMed

UCB, Inc.

Health Canada Drug Product Database

Ready to proceed? Place your request for the patch today with prompt, express shipping and US shipping from Canada. Always use as directed by your prescriber. This information is not a substitute for medical advice.