Nobivac® Canine 1-DAPPv Vaccine for Dogs

Nobivac Canine 1-DAPPv is a core vaccine for dogs. It helps protect against distemper, adenovirus, parainfluenza, and parvovirus in healthy canines. This page explains how the vaccine works, who it fits, and how to handle it for safe use, with US delivery from Canada and details on paying without insurance.

What Nobivac Is and How It Works

Nobivac® Canine 1-DAPPv is a modified-live, combination vaccine for dogs six weeks of age or older. It contains antigens to stimulate protective immunity against distemper virus, adenovirus type 2, parainfluenza virus, and parvovirus. As a combination product, the DAPP components reduce injections compared with giving separate shots.

Canine Distemper can cause respiratory, gastrointestinal, and neurologic signs. Adenovirus is linked to infectious hepatitis and can affect the liver and eyes; see Canine Adenovirus Infectious Hepatitis for background. Parainfluenza contributes to kennel cough complexes. Parvovirus is a severe gastrointestinal infection; read more under Canine Parvovirus.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This DAPPv vaccine for dogs works by presenting weakened organisms so the immune system learns to recognize them. The treatment does not cause disease in healthy animals when used as directed. After a complete series and on-time boosters, many dogs maintain durable responses, though schedules can vary by risk and local guidance.

Who It’s For

DAPPv for dogs is considered a core immunization for most puppies and adult canines. Healthy animals at least six weeks old can receive primary vaccination. Dogs with uncertain protection, shelter intakes, and animals in boarding settings may also benefit when assessed by a veterinarian.

Do not vaccinate dogs that are acutely ill, severely immunocompromised, or known to have had life-threatening vaccine reactions. Use caution in pregnant animals. Maternal antibodies in young puppies may blunt responses, which is one reason a series across early weeks is recommended.

Dosage and Usage

The label directs a 1 mL dose given subcutaneously or intramuscularly. For the puppy series, begin at six weeks of age or older, then administer doses every three to four weeks until at least 16 weeks of age. Adult dogs with unknown status often receive an initial dose and a follow-up per veterinarian direction. Revaccination is typically done annually or as recommended by your prescriber.

Nobivac 1 DAPPv should be reconstituted immediately before use with the supplied diluent, shaken gently, and used promptly. Administer at a consistent time during scheduled visits. Observe dogs after injection, and keep them quiet and monitored for a short period. Follow the official product insert for detailed administration instructions.

Strengths and Forms

This product is supplied as a lyophilized cake with sterile diluent for reconstitution. It is commonly available in single-dose vials for clinical use, and in clinic packs. Availability can vary by lot and location.

• Nobivac 1 DAPPv single dose presentation
• Nobivac Canine 1 DAPPv 25×1 dose clinic packaging

Packaging and labeling may differ by market. Always confirm the exact product before you order.

Missed Dose and Timing

If a puppy series is delayed, the series is usually continued rather than restarted; clinicians may adjust timing. If a booster window is missed, your prescriber may recommend a dose as soon as practical and update the schedule. Do not give extra doses without direction. Follow the label and seek veterinary guidance when schedules are disrupted.

Storage and Travel Basics

Store refrigerated and protect from light. Do not freeze. Keep in the original packaging until reconstitution. Use immediately after mixing, and discard any unused portion safely. For travel, transport in an insulated container with cold packs to maintain recommended temperature and avoid direct contact with ice. Minimize time out of refrigeration. Keep out of reach of children and animals. Temperature-controlled handling when required supports product integrity during transit.

If you plan to carry doses across borders or state lines, bring purchase documentation and check any local restrictions. Dispose of needles and syringes in a puncture-resistant sharps container according to local rules.

Benefits

This combination protects against four serious pathogens in one visit, reducing injections and clinic time. The therapy can be integrated into standard puppy and adult wellness plans. Single-dose vials simplify inventory and administration in clinics and shelters. As part of core immunization, it supports community disease control for canine populations.

Canine DAPPv vaccine may reduce the risk of severe illness, hospitalization, and prolonged recovery associated with parvovirus and distemper. Protection against adenovirus and parainfluenza contributes to respiratory and systemic health, especially in group housing or social environments.

Side Effects and Safety

• Injection-site tenderness or mild swelling
• Transient lethargy
• Brief fever
• Reduced appetite

Serious reactions can include hypersensitivity or anaphylaxis, facial swelling, hives, vomiting, or collapse. Rare events such as immune-mediated responses have been reported with vaccines in general. Seek immediate veterinary care if severe signs occur. Inform your prescriber about previous reactions before future doses. Observe animals after vaccination and report concerns promptly.

Drug Interactions and Cautions

Immunosuppressive therapies, including high-dose corticosteroids or certain chemotherapeutics, may blunt vaccine responses. Concurrent administration with other biologics should follow label guidance and veterinarian advice. Maternal antibodies can interfere with early puppy responses, which is why a series is recommended. Do not mix this vaccine with other products in the same syringe unless the label specifically indicates compatibility.

What to Expect Over Time

Responses build across the series and after boosters. Puppies often need several visits before robust protection develops. Adult dogs may maintain protection with periodic revaccination per local risk and clinic protocols. Monitor for mild, short-lived post-vaccination effects. For a high-risk environment, prescribers may adjust timing to align with exposure patterns.

A DAPPv puppy vaccine is one part of a broader wellness plan, which can include parasite control, nutrition, and routine checkups. Keep documentation of each dose to support boarding, training classes, and travel requirements.

Compare With Alternatives

Some clinics prefer enhanced formulations or packaging differences. For a similar spectrum with an alternative presentation, consider Nobivac Canine Edge 1 Dappv. For situations focusing on early parvo and distemper protection, Nobivac Puppy Dpv may be used as directed by a veterinarian. Nobivac DAPPv products are often selected based on clinic workflow, age, and risk.

Pricing and Access

Our platform highlights Canadian pricing and US fulfilment options to help clinics and owners plan purchases. This item Ships from Canada to US through licensed channels. Review current offers and see how cash-pay orders can fit different budgets. If you are looking for deals, visit our Promotions page for rotating savings.

You can compare options in Pet Medications and confirm origin details under Canada before you place an order.

Availability and Substitutions

Supply can vary. If a selected presentation is unavailable, a prescriber may recommend an alternative with a matching spectrum or schedule. Do not substitute vaccines without veterinary oversight, especially during a puppy series. Check stock before scheduling clinics to avoid gaps.

Patient Suitability and Cost-Saving Tips

Most healthy dogs are candidates for core DAPP immunization. Animals with prior severe reactions, current illness, or those on immunosuppressive therapies may require adjusted timing or different plans. For shelters and high-volume settings, single-dose vials can help reduce waste compared with multi-dose formats.

• Bundle visits: align boosters with other care
• Order clinic packs: reduce per-dose costs
• Set reminders: keep schedules on track
• Plan ahead: confirm stock before clinics

To stretch budgets, consider scheduling your order to coincide with upcoming clinics and using multi-pack formats when appropriate. For broader pet health reading, see Doxycycline For Dogs and Drontal For Dogs as examples of supportive therapies for different conditions.

Questions to Ask Your Clinician

• Is my dog ready to start the DAPP series now?
• Which schedule fits age, exposure, and local risk?
• Can this be given with other vaccines the same day?
• What post-vaccination signs should I watch for at home?
• How should I handle and store doses for transport to the clinic?
• What documentation do I need for boarding or travel?

Authoritative Sources

Merck Animal Health – Nobivac Canine PortfolioProduct Insert – Nobivac DAPPv (US)USDA Center for Veterinary Biologics – Licensed Products

Ready to proceed? You can place your order with prompt, express shipping, and we will support safe handling throughout the process. This content is informational and not a substitute for professional veterinary advice; always follow the official label and your clinician’s guidance.