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Orthovisc® Injection for Knee Osteoarthritis
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Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
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$496.99
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This page explains a knee osteoarthritis injection used to reduce pain and improve joint function. You can access it with US delivery from Canada. If you pay without insurance, we outline practical ways to manage costs and plan refills.
What Orthovisc Is and How It Works
Orthovisc® contains high–molecular weight hyaluronan, a form of sodium hyaluronate. It is injected into the knee joint to supplement synovial fluid. The treatment can improve lubrication and cushioning, which may reduce pain during movement. By restoring viscosity, it may help the joint glide more smoothly.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This is a viscosupplement injection for knee osteoarthritis. It is given by a trained clinician in a medical setting. The series approach aims to provide relief over a treatment cycle, with effects that can build across injections.
Who It’s For
This medicine is intended for adults with knee osteoarthritis who have symptoms such as pain, stiffness, or reduced function. Orthovisc for knee pain is considered when simple measures and oral pain relievers are not enough, or when patients wish to avoid frequent oral NSAID use. People with known allergies to hyaluronan products or gram-positive bacterial proteins should not receive it. Avoid use if there is an infection or skin disease at the injection site. Your clinician will evaluate your joint and medical history to confirm suitability.
Some patients may also discuss oral options to complement non-drug strategies. For background on therapy choices, see our condition pages for Osteoarthritis and Pain Inflammation.
Dosage and Usage
The typical schedule is one intra-articular injection into the affected knee once weekly for several weeks. Many treatment courses use three injections; some may use a four-injection series, as directed by the prescriber. The entire dose in the prefilled syringe is administered into the knee joint. sodium hyaluronate injection 30 mg/2 mL is delivered by a healthcare professional under aseptic technique.
Before the injection, the clinician may remove excess joint fluid. You will be asked to avoid strenuous activity for a short period after each dose. Follow your prescriber’s instructions on activity limits and post-injection care. Do not self-inject or attempt to reuse any supplies.
Strengths and Forms
Available presentation: Orthovisc 30 mg/2 mL in a single-use prefilled syringe for intra-articular use. Packaging and labeling can differ by market. Availability may vary based on supplier and stock.
Missed Dose and Timing
If you miss an appointment, contact your clinic to reschedule the next injection. Try to maintain weekly intervals when possible. If timing shifts, your clinician will guide how to complete the series. Do not receive extra injections to “catch up” without medical advice.
Storage and Travel Basics
This product is clinic-administered and should be stored according to the official label, typically at controlled room temperature and protected from freezing. Keep syringes in original packaging until use. If you are transporting your prescription to a clinic, keep it in the carton, avoid extreme temperatures, and do not open or heat the syringe. Ask the clinic to store it until administration. Use child-safe practices: keep out of reach of children and pets.
When traveling, carry documentation of your prescription and keep the package in your hand luggage. Avoid direct sunlight and car dashboards. A pharmacy or clinic can advise on handling and timing. Our partners support encrypted checkout and temperature-controlled handling when required.
Benefits
This treatment can reduce knee pain and improve function for osteoarthritis. It supplements joint lubrication, which may help with walking, daily activities, and exercise tolerance. Because it is localized to the joint, it may be suitable for patients seeking to limit systemic exposure from chronic oral analgesics. A defined series also allows planning around activities and physical therapy.
Side Effects and Safety
- Injection-site pain or swelling
- Joint stiffness or warmth
- Temporary fluid accumulation
- Mild bruising or redness
Serious reactions are uncommon but can include severe joint inflammation or infection, allergic reactions, or significant swelling requiring medical care. Tell your clinician about any allergies, bleeding problems, prior knee infections, or recent skin conditions near the injection site. If you use blood thinners or have a history of immune reactions to hyaluronan products, discuss risks before treatment.
Drug Interactions and Cautions
There are no widely recognized systemic drug interactions because this therapy acts locally within the joint. Still, inform your clinician about all medicines and supplements, including anticoagulants and intra-articular steroids. The injection should not be placed into an infected or severely inflamed joint. Avoid strenuous weight-bearing activity for 48 hours after each dose unless your prescriber advises otherwise.
What to Expect Over Time
Many patients notice gradual changes across the series, with comfort and function improving as the course progresses. You may find walking, climbing stairs, or exercise feels easier. Responses vary. Consistent scheduling, activity moderation after each dose, and adherence to physical therapy can support outcomes. If your knee symptoms remain significant after a complete course, your clinician may reassess the diagnosis, discuss alternative therapies, or plan a future series.
Compare With Alternatives
Another hyaluronate option is Durolane, which is given as a single injection in many cases. Patients who prefer oral therapy may consider the NSAID Celecoxib, where appropriate. Your clinician can explain differences in visit frequency, administration, and expected symptom control.
Pricing and Access
Save with Canadian pricing and seamless U.S. access. We help you compare options, estimate series needs, and plan refills around your clinic schedule. If you are evaluating the Orthovisc price, view our current listing and consult your prescriber on the expected number of injections in a course. We support US shipping from Canada and coordinate verified prescriptions before dispensing.
Looking for neutral savings info and seasonal offers? See our Promotions page for current updates. For arthritis education and adjunct options, explore Celebrex Arthritis and Meloxicam Dosage. You can also browse by origin via Canada.
Availability and Substitutions
Supply can vary. If this item is unavailable, a prescriber may recommend an appropriate alternative hyaluronate or adjust timing. We do not guarantee restock dates. Your clinic can advise on scheduling, and we can help you review comparable therapies carried on our site.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults with knee osteoarthritis who have not achieved adequate relief with activity modification, topical agents, or oral analgesics. It is not for people with joint infections or known hypersensitivity to hyaluronan. To manage expenses, consider multi-month planning for both knees if your clinician anticipates bilateral treatment over time. Align your purchase with scheduled appointments to avoid storage at home. Set reminders for follow-up injections so you do not miss weekly intervals. Discuss physical therapy and weight-bearing guidance to support joint health between visits.
Questions to Ask Your Clinician
- Series plan: three or four injections for my knee?
- Joint aspiration: will you remove fluid before dosing?
- Activity: what should I avoid after each injection?
- Co-therapy: can I use topical NSAIDs or acetaminophen?
- Future planning: when might a repeat series be considered?
Authoritative Sources
Review official information before starting treatment:
Ready to proceed? You can order Orthovisc online with prompt, express shipping, supported by pharmacist review and your clinician’s prescription. This content is educational and does not replace medical advice. Always follow your prescriber’s instructions and the official label.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
How long does knee relief usually last after a series?
Response varies. Some people notice benefits building across the series, with comfort and function improving over weeks. Others may need more time or a different approach. Relief duration can depend on osteoarthritis severity, activity level, and adherence to activity guidance and physical therapy. If pain persists or returns, your clinician may reassess your joint, consider a repeat series at an appropriate interval, or recommend an alternative therapy tailored to your needs.
Can both knees be treated during the same period?
Clinicians sometimes treat both knees in a similar timeframe, scheduling separate injections for each knee. Your plan depends on symptoms, exam findings, and overall health. Doing both knees can help coordinate visits and rehabilitation. It can also affect budgeting and appointment timing, so discuss logistics with your clinic. Your prescriber will determine the appropriate sequence and spacing to balance comfort, safety, and activity goals.
What should I expect at the injection visit?
A clinician will assess your knee, clean the skin, and may remove excess joint fluid. The medicine is placed directly into the joint space using a sterile technique. Afterward, light activity is usually fine, but you may be told to avoid strenuous exercise or prolonged standing for a short period. Temporary soreness, warmth, or swelling can occur. Ask how to use ice and when to resume usual routines. Seek medical care if severe pain or fever develops.
Is this therapy compatible with oral NSAIDs or acetaminophen?
Many patients use nonprescription pain relievers or topical agents alongside joint injections. Your prescriber can advise on appropriate options and timing. Oral NSAIDs may have gastrointestinal, kidney, or cardiovascular risks, especially with long-term use. Acetaminophen has separate dosing limits. Always share your full medication list and medical history, and ask about the safest plan for your situation.
What if I miss an appointment during the series?
Call the clinic to reschedule as soon as possible. Try to maintain the weekly spacing between injections when feasible. Your clinician will guide how to complete the series if timing shifts. Do not receive extra injections without professional direction. Keep reminders for future appointments and plan transportation in advance to help stay on schedule throughout the course.
Can I store the syringe at home before the visit?
Storage is usually managed by clinics, but if you must transport your prescription, keep it in the original carton, avoid heat and freezing, and bring it directly to your appointment. Do not open the package or attempt to sterilize anything. Keep it away from children and pets. Ask the clinic to confirm storage details based on the labeled product supplied to you. When in doubt, defer to the official label and your prescriber.
How does this differ from single-injection options?
Some viscosupplements are given as a one-time dose, while others use a multi-injection series. Differences include visit frequency, volume delivered, and how clinicians tailor the plan. Single-dose options can reduce visits, while multi-dose series may allow incremental improvement over time. Efficacy and convenience vary by product and patient needs. Your clinician can explain which approach aligns with your goals and schedule.
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