Prascend® Tablets for Horses

Prascend is a pergolide mesylate tablet used to control signs of equine Cushing’s disease, also called PPID. This page explains how the treatment works, safe use, and access options for ongoing care. US delivery from Canada helps you manage therapy costs without insurance.

What Prascend Is and How It Works

Cushings Disease in horses is driven by overactive pituitary tissue that increases certain hormones. Prascend® is a dopamine agonist that helps rebalance those hormones and reduce clinical signs such as long hair coat, muscle loss, and increased drinking and urination. It supports steady management rather than a cure.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

These pergolide tablets for horses act on dopamine receptors in the pituitary. The effect may reduce ACTH-related hormone production. Many horses need ongoing therapy and periodic reassessment by a veterinarian. Always follow the approved label for dose adjustments and monitoring.

For country-of-origin details, see our attribute page for Canada.

Who It’s For

This treatment is indicated to control clinical signs associated with PPID in adult horses. Horses with classic signs, or laboratory-confirmed PPID, may benefit when a prescriber recommends therapy. Use only under veterinary supervision.

Prascend tablets for horses are not for animals intended for human consumption. Use caution in breeding, pregnant, or lactating mares. Avoid if the animal has known hypersensitivity to pergolide or related agents. Discuss other health conditions and current medicines with your veterinarian before starting.

Dosage and Usage

Typical dosing starts low and is adjusted by the veterinarian based on response. Label guidance describes once-daily administration by mouth. Many horses receive a partial tablet at initiation, with careful titration after clinical review.

Give with a small amount of feed if needed to encourage acceptance. Tablets can be split to achieve the instructed dose. Do not change the dose on your own. If the horse shows decreased appetite or other changes, contact the prescriber before altering therapy. For full directions, follow the official product label.

Caregivers should wash hands after handling. Women who are pregnant or may become pregnant should avoid direct contact with fragmented tablets. Keep all medicines away from children and animals.

Strengths and Forms

The product is supplied as scored oral tablets in blister packs for accurate dosing. Availability can vary by pack size and supplier.

Commonly published presentation: Prascend 1mg tablets for horses. Your veterinarian will determine the daily amount from this strength to match the horse’s weight and response. Selection of pack count may depend on the stable’s refill plan.

Missed Dose and Timing

If a dose is missed, give it when remembered the same day. If it is nearly time for the next scheduled dose, skip the missed one and resume regular dosing. Do not double up doses. Keep a simple chart to track daily administration and reduce errors.

Storage and Travel Basics

Store tablets in the original blister to protect from moisture. Keep at room temperature as directed on the label and away from direct sunlight. Do not store in the tack room if it is very humid. Keep out of reach of children and other animals. When traveling, carry the prescription and the original packaging for verification if asked.

For longer trips, pack a few extra days of tablets in case of delays. Use a secure container and keep a copy of the veterinarian’s directions. Our fulfilment uses temperature-controlled handling when required.

For broader veterinary needs while traveling or at shows, explore our Pet Medications category.

Benefits

This class helps manage hormone imbalance associated with PPID. Many horses show improved coat shedding, more stable body condition, and better energy. Once-daily dosing supports barn routines. Scored tablets allow fine-tuning under veterinary guidance. Ongoing monitoring and consistent administration can help maintain control of clinical signs over time.

Side Effects and Safety

• Decreased appetite or inappetence
• Lethargy or reduced activity
• Diarrhea or soft stool
• Colic signs
• Sweating or mild agitation

Some horses may experience behavioral changes or ataxia. If severe reactions occur, contact your veterinarian promptly. Dose changes should be guided by the prescriber only. Horses with concurrent illnesses need careful oversight. In rare cases, sensitivity may require discontinuation.

Drug Interactions and Cautions

Drugs that oppose dopamine effects may reduce response, including phenothiazines, some antiemetics, and domperidone. Sedatives and blood pressure–lowering agents may require caution. Always provide your veterinarian a complete list of supplements, dewormers, and other medicines.

Use care if other endocrine therapies are in place. The label advises veterinary evaluation before combining new medicines. These pergolide tablets should only be started or adjusted by the prescriber.

What to Expect Over Time

It may take steady daily use and routine check-ins for noticeable changes. Your veterinarian may recheck clinical signs and recommend periodic lab monitoring. Dose adjustments can occur as the horse’s condition evolves seasonally. Keep feeding, turnout, and farrier care consistent, and track changes in coat, water intake, and attitude. Stable records help you and the prescriber evaluate progress.

Compare With Alternatives

For PPID in horses, pergolide is the established therapy on label. When tablets do not suit a particular horse, prescribers may discuss other approaches or supportive care. For endocrine conditions in other species that we carry, see Vetoryl® for canine hyperadrenocorticism and Thyro Tab® for hypothyroidism in dogs. Your veterinarian will determine what is clinically appropriate for your animal.

Pricing and Access

Canadian sourcing can offer value compared with local cash-pay options. For barns planning refills, pack size selection supports routine scheduling. If you prefer smaller packs, ask about Prascend 60 tablets during checkout. For larger refills, consider multi-pack requests if your prescription allows.

Ships from Canada to US, with transparent pricing shown at checkout. You can review the current listing and see availability before placing an order. If you are looking for seasonal deals, check our Promotions page. Discuss total costs without insurance with your veterinarian if budgeting across diagnostics, farrier care, and feed.

Availability and Substitutions

Supply and pack counts can vary. If a specific pack is unavailable, your prescriber may recommend an alternative plan or a different count to maintain continuity. We do not provide restock dates; please check the product page for current status. Any substitution decisions should be made by the veterinarian.

Patient Suitability and Cost-Saving Tips

Good candidates are horses with confirmed or strongly suspected PPID where the clinician recommends treatment. Horses with severe systemic illness, or breeding mares, need careful risk–benefit discussions. Not for animals intended for the food chain.

Cost planning tips include ordering enough tablets to cover your next recheck, using barn calendars for reminders, and aligning refills with farrier or dental visits. Multi-month refills can reduce repeated courier fees when prescriptions permit. Keep dosing logs, and request refill reminders so you never run short before a veterinary review.

If you manage other conditions at the stable, see supportive options like Cerenia® for nausea, Onsior Dog® for postoperative pain in dogs, and Antirobe® for certain dental infections in pets. For endocrine adrenal support in dogs, review Zycortal® with your veterinarian.

Questions to Ask Your Clinician

• Diagnosis plan: Which clinical signs and tests support a PPID diagnosis?
• Dose selection: What starting dose and schedule fit my horse today?
• Monitoring: Which follow-up checks or ACTH tests should we plan?
• Side effects: What early signs suggest dose adjustment is needed?
• Feed and turnout: Do diet or exercise changes support this therapy?
• Hoof care: How should we coordinate farrier care for laminitis risk?
• Long-term plan: How often will we reassess and consider dose changes?

Authoritative Sources

Boehringer Ingelheim Animal Health (US)

FDA NADA 141-331 (Prascend)

Health Canada Drug Product Database

Ready to proceed? You can add to cart for your prescription and choose fulfilment with prompt, express shipping and US shipping from Canada. Always follow your veterinarian’s directions.