Renvela® Tablets for Hyperphosphatemia

Renvela is a phosphate binder for adults with chronic kidney disease on dialysis. It helps reduce high phosphorus by binding dietary phosphate in the gut. This page explains how it works, safe use, and how US delivery from Canada may help you manage costs without insurance.

What Renvela Is and How It Works

Renvela® contains sevelamer carbonate, a non-absorbed polymer that binds phosphate in the gastrointestinal tract. By trapping phosphate from food, it lowers the amount absorbed into the bloodstream and helps manage Hyperphosphatemia in people on dialysis. This treatment does not contain calcium, aluminum, or iron, which helps reduce the chance of calcium loading or metal-related issues.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

The class can be used alone or with other binders based on your prescriber’s plan. It is taken with meals so it can bind the phosphate you eat. Swallowing tablets whole is important; the powder option can be considered for those who have trouble swallowing.

Who It’s For

This medicine is used to control high serum phosphorus in adults with chronic kidney disease on dialysis. It may be considered in people who should avoid calcium-based binders or who need additional binding capacity. People with a history of bowel obstruction should not use it. Tell your healthcare professional about swallowing difficulties, severe gastrointestinal problems, or recent abdominal surgery before starting.

Dosage and Usage

Follow your prescriber’s directions and the official label. Starting doses are typically based on your current serum phosphorus and whether you are switching from another binder. The dose is taken three times daily with meals. Your prescriber may adjust the dose during follow-up visits to maintain target phosphorus.

Swallow tablets whole with liquid. Do not crush, chew, or break the tablets. For the oral powder, mix the entire packet contents with water and drink promptly. Take this therapy at the same meals each day to support consistent binding.

Use medicines that must be given apart from binders at the specified intervals provided by your clinician. Ask your dialysis team or pharmacist to review your full medication list. If you have dosing questions, defer to the package insert and your prescriber. Renvela dosage should always be individualized by a clinician based on labs and response.

Strengths and Forms

Common options include film-coated tablets and an oral powder for suspension. Availability can vary by pharmacy and manufacturer.

• Sevelamer carbonate 800 mg tablets
• Oral powder packets for suspension

Not all pack sizes are stocked at all times. Your prescriber may recommend brand or generic based on your needs.

Missed Dose and Timing

If you miss a dose with a meal, skip it and take the next dose with your next meal. Do not double up to make up for a missed dose. Keeping doses tied to meals helps the binder work where it is needed.

Storage and Travel Basics

Store at room temperature in the original container, away from moisture. Keep the bottle tightly closed and out of reach of children and pets. When traveling, carry this medicine in your hand luggage along with a copy of your prescription. Use a pill organizer only if it keeps tablets protected from humidity. For liquids or powders, reseal packets as directed after mixing. Pharmacies use temperature-controlled handling when required; ask your pharmacist if you have questions about transit conditions.

Benefits

This treatment binds dietary phosphate to help maintain target serum levels. It is not systemically absorbed, so its action remains in the gut. Being calcium- and metal-free may reduce the need to track calcium load or iron intake from binders. The oral powder can support patients who cannot swallow tablets. Consistent use with meals, plus dialysis and diet guidance, works together to manage phosphorus.

Side Effects and Safety

• Common effects: nausea or vomiting
• Digestive changes: constipation, diarrhea, gas
• Abdominal discomfort: pain or bloating
• Stool changes: harder stools or more frequent stools

Serious but less common risks include bowel obstruction, ileus, or perforation, especially in people with prior major gastrointestinal disease or surgery. Difficulty swallowing can occur with tablets; talk to your prescriber about powder options if you have dysphagia. Vitamin levels, including fat-soluble vitamins, may need monitoring as advised by your clinician. Seek urgent care for severe abdominal pain, persistent vomiting, or signs of bowel blockage. Report any new or worsening symptoms to your dialysis team promptly. Renvela side effects should be discussed with your clinician, especially if they do not improve.

Drug Interactions and Cautions

Sevelamer can reduce the absorption of certain medicines taken at the same time. Separate dosing from sensitive drugs as directed by the label and your prescriber. Notable interactions include:

• Antibiotics: especially fluoroquinolones like ciprofloxacin
• Thyroid hormones: levothyroxine may require TSH monitoring
• Immunosuppressants: tacrolimus or cyclosporine monitoring may be needed
• Antiarrhythmic and antiseizure medicines: discuss timing with your clinician

Always provide a full medication and supplement list to your healthcare professional. Do not change doses on your own.

What to Expect Over Time

Your prescriber will check phosphorus regularly and adjust the dose if needed. Many people require slow, careful titration, guided by dialysis labs and diet counseling. Taking each dose with meals is key to consistent control. If you experience gastrointestinal effects, discuss options like meal adjustments, hydration, or switching to powder. Adherence can improve day-to-day symptoms related to high phosphate and help meet long-term treatment goals set by your dialysis team.

Compare With Alternatives

Phosphate binders come in several classes. Calcium-based options bind phosphate but add calcium load. Iron-based binders offer another choice. Non-calcium, non-metal polymers are a widely used approach.

We also carry Velphoro (sucroferric oxyhydroxide), an iron-based binder that some prescribers choose. Other options your clinician may consider include calcium acetate or ferric citrate. Choice depends on labs, pill burden, tolerance, and other conditions. These are prescription decisions managed by your healthcare professional.

Pricing and Access

Canadian pharmacy pricing can offer meaningful savings compared to typical cash-pay in the U.S. Availability and pack sizes vary by manufacturer. For current offers, check our site listings. Sevelamer carbonate 800 mg price information appears on each product page so you can compare options. This item Ships from Canada to US with transparent fees.

Looking for deals? Visit our Promotions page for active discounts. For origin details, see Canada on select product pages. We use encrypted checkout to protect your information. If you have questions about insurance, your prescriber can advise on coverage, while we focus on cash-pay options.

Availability and Substitutions

Brand and generic options may both be available. A prescriber may recommend a substitution if your usual product is temporarily out of stock. Generic sevelamer carbonate is commonly used in dialysis programs when appropriate. If a specific strength or pack is unavailable, your clinician can advise on alternatives and titration with available units. Generic Renvela sevelamer carbonate may be an option when authorized by your prescriber.

Some buyers prefer a particular manufacturer for consistency. If you have that preference, add a note at checkout and we will coordinate when possible. Product categorization for browsing is available under Other. For dosage-unit specifics, refer to your label rather than online summaries. Sevelamer carbonate 800 mg tablets may not be stocked at all times.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults on dialysis who need a calcium-free binder or who have not tolerated other binders. It may not suit people with a history of bowel obstruction or severe swallowing problems. Always review your medical history with your prescriber.

• Multi-month fills: reduce trips and help keep adherence steady
• Refill reminders: set alerts tied to your dialysis schedule
• Diet alignment: coordinate with your renal dietitian for meal timing
• Pill burden: ask about powder if tablets are difficult
• Compare options: review brand vs generic availability

For budgeting, compare out-of-pocket quotes across sizes and manufacturers. If you need a discount, a Renvela cash price comparison on our site can help you plan. You can also review diabetes support content if you manage CKD and diabetes together, such as Different Types Of Insulin, Lantus Insulin Uses, and National Diabetes Month 2025.

Questions to Ask Your Clinician

• What phosphorus target should I aim for with this binder?
• How will we adjust the dose based on my dialysis labs?
• Should I take any medicines at a different time to avoid interactions?
• Is the powder a better option for me due to swallowing concerns?
• Do I need vitamin monitoring or supplements during treatment?
• What signs of bowel blockage should prompt urgent evaluation?

Authoritative Sources

FDA DailyMed

Manufacturer

Health Canada DPD

Ready to proceed with your prescription? You can place an order with prompt, express shipping and US shipping from Canada. This site is informational and does not replace your clinician’s advice or the official label.