Aldactone® Tablets for Hypertension and Edema

Spironolactone is a potassium-sparing diuretic used for fluid buildup and blood pressure control. This page explains key uses, safety, and how to access treatment with US delivery from Canada. You can compare options for Spironolactone without insurance.

What Aldactone Is and How It Works

Aldactone® contains spironolactone, an aldosterone receptor antagonist. It helps your body release water and sodium while retaining potassium. This action reduces swelling from conditions like heart failure and cirrhosis and supports blood pressure management. It may also be prescribed for confirmed primary hyperaldosteronism.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

The medicine works at the distal nephron to counter aldosterone’s effects. It can lower blood pressure, reduce edema, and ease symptoms related to excess aldosterone. Because it spares potassium, clinicians monitor electrolytes and kidney function during ongoing therapy. See our category guide on Potassium Sparing Diuretics to learn how this class compares with others.

Who It’s For

This therapy is indicated for heart failure–related edema, cirrhotic ascites, nephrotic edema, essential hypertension, and primary hyperaldosteronism diagnosed by testing. Some people should avoid it, including those with anuria, acute kidney failure, or baseline high potassium. Your prescriber will decide if Aldactone tablets are appropriate alongside other treatments. For hypertension education, you can also review Hypertension and the overview in Atenolol Uses.

Dosage and Usage

Follow your prescription label. Many adults take it once daily; some take divided doses. Take consistently with or without food. Try to take it at the same time each day, which helps routine and reduces missed doses. Swallow whole with water. This is a diuretic, so morning dosing can help limit nighttime bathroom trips. Discuss lab monitoring with your healthcare professional and follow any instructions on salt substitutes or potassium intake.

Your prescriber may adjust the schedule based on kidney function, potassium levels, and treatment goals such as edema control or blood pressure support. Never change your dose on your own. If you also take loop or thiazide diuretics, your care team may coordinate timing to balance effect and tolerability. For general class guidance, see our Diuretics category.

If tablets are scored, your prescriber may decide whether splitting is suitable. Always use a proper tablet cutter if instructed to split. Avoid crushing unless your clinician says it is acceptable for your specific product.

Strengths and Forms

This medicine is supplied as oral tablets in multiple strengths. Common presentations include 25 mg, 50 mg, and 100 mg tablets. Availability can vary by manufacturer and by pharmacy. If your exact strength is not in stock, your prescriber may provide a suitable alternative tablet strength or a temporary plan.

Ask your pharmacist about tablet appearance and imprint if you switch manufacturers. The labeled active ingredient remains spironolactone. When needed, your clinician can help align refills with your lab schedule for safe ongoing use. This section includes the exact term Spironolactone 25 mg for clarity on one common strength.

Missed Dose and Timing

If you miss a dose, take it when remembered the same day. If it is close to the next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. If you miss doses frequently, set reminders or ask your pharmacist about adherence tools. Consistency supports stable blood pressure and fluid balance.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from moisture and light. Keep them in the original, child-resistant container with the label intact. Do not store in a bathroom. When traveling, pack enough for the full trip plus a few extra days in case of unexpected delays. Carry medicines in your hand luggage with a copy of your prescription and clinic contact information. If you use a pill organizer, keep at least one container with the original label for security checks.

Dispose of expired or unused tablets through community take-back programs when available. If none exist, ask your pharmacist for safe disposal guidance. As a micro trust cue for shipments, we use encrypted checkout and follow temperature-controlled handling when required.

Benefits

This treatment helps your body shed excess fluid while limiting potassium loss. It can support blood pressure goals and reduce swelling from certain conditions. Because it targets aldosterone, it may help address symptoms tied to hormonal fluid retention. Once-daily dosing is common, which many patients find convenient. Review class information under Cardiovascular to see how therapies are organized by condition.

Side Effects and Safety

• Increased urination
• Dizziness or lightheadedness
• Headache
• Gastrointestinal discomfort
• Breast tenderness or menstrual changes
• Fatigue

Serious risks can include high potassium, kidney function changes, and very low blood pressure. Contact a clinician right away with severe weakness, slow or irregular heartbeat, fainting, or little to no urination. Because spironolactone can raise potassium, your prescriber may limit potassium-rich salt substitutes or supplements. Report persistent gastrointestinal issues, rash, or endocrine-related effects such as gynecomastia to your care team.

Drug Interactions and Cautions

Tell your clinician about all medicines and supplements. Notable interactions include ACE inhibitors and ARBs, potassium supplements, trimethoprim-containing antibiotics, cyclosporine, tacrolimus, NSAIDs, and lithium. Digoxin levels can be affected. Alcohol and other blood pressure therapies may increase dizziness. If you are also taking agents that impact potassium, your care team will determine appropriate lab monitoring. For broader blood pressure therapy context, explore Heart Failure resources.

What to Expect Over Time

Many people notice gradual improvement in swelling and blood pressure with regular use. Your healthcare professional may schedule blood tests to monitor potassium and kidney function. Staying consistent with dosing, keeping follow-up visits, and following dietary guidance can help the plan work as intended. If your condition changes or you have new symptoms, contact your prescriber to review the regimen.

Compare With Alternatives

Some patients may use a different potassium-sparing diuretic, or a fixed-dose combination. Your clinician may consider Triamterene as a class alternative in select cases. Others may benefit from the combination product Spironolactone HCTZ to address fluid retention and blood pressure together. If you currently use Generic spironolactone, any change should be guided by your prescriber, considering labs and your treatment goals.

Pricing and Access

You can review current Spironolactone price options on this page and compare Canadian sources. We provide transparent details so you can plan refills and discuss costs with your clinician. Ordering is prescription-based, and verification is part of our process. This product ships to most U.S. addresses and typically Ships from Canada to US. If you are looking for seasonal deals, check our Promotions page for current offers.

Availability and Substitutions

Supply may vary by strength and manufacturer. If your exact item is temporarily unavailable, your prescriber may recommend a different tablet strength or an alternative medicine. Pharmacists can coordinate with your clinician to ensure the substitute aligns with your diagnosis and monitoring plan. We do not promise restock dates, but we aim to keep you informed about options for continuity of therapy.

Patient Suitability and Cost-Saving Tips

This medicine may be a good fit for adults whose conditions and labs support use of an aldosterone antagonist. It may not be suitable for people with high baseline potassium or severe kidney impairment. Ask your clinician about multi-month supplies to reduce refill visits. Set reminders so you do not miss doses. If budget is a concern, browsing Spironolactone online options on our site can help you compare sources and plan ahead. Align refills with upcoming lab checks when possible.

Questions to Ask Your Clinician

• How will we monitor potassium and kidney function?
• Should I avoid salt substitutes or high-potassium foods?
• What signs of low blood pressure should I watch for?
• Is once-daily dosing right for me, or should I split doses?
• If I switch manufacturers, do I need any new counseling?
• How do my other medicines affect safety on this therapy?

Authoritative Sources

FDA DailyMed

US Prescribing Information

Health Canada DPD

Ready to proceed? You can place your order now for prompt, express shipping with US shipping from Canada. This content is educational and does not replace your clinician’s advice.