Trulicity® Injection for Type 2 Diabetes

This once-weekly injectable medicine helps manage type 2 diabetes in adults. You get US delivery from Canada, plus straightforward details on the Trulicity® price without insurance.

What Trulicity Is and How It Works

Trulicity® contains dulaglutide, a GLP-1 receptor agonist. It helps lower blood sugar by increasing insulin release when glucose is high and reducing glucagon. It also slows stomach emptying, which may help with appetite control. The pen is a single-dose, prefilled autoinjector used once each week.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This treatment is taken alongside diet and exercise. It is not insulin. It may be used alone or with other diabetes medicines under a prescriber’s direction. For broader context on treatment options, see our Type 2 Diabetes hub and the Diabetes Drugs List.

Who It’s For

Many adults use Trulicity for type 2 diabetes to improve blood sugar control. It is not for type 1 diabetes or diabetic ketoacidosis. People with a personal or family history of medullary thyroid carcinoma or with MEN2 should not use this class. If you have had pancreatitis, severe gastrointestinal disease, or serious stomach problems, your clinician may choose another option.

Discuss your medical history, current medicines, and goals with a healthcare professional before starting this therapy. Explore comparative insights in Trulicity Vs Ozempic to understand how GLP-1 options differ.

Dosage and Usage

The pen is injected once weekly, on the same day each week, with or without meals. Commonly, treatment starts at 0.75 mg once weekly. If additional effect is needed and the medicine is well tolerated, prescribers may increase the dose in steps at appropriate intervals. Follow your prescriber’s directions and the official patient instructions that come with your pen.

Inject subcutaneously into the abdomen, thigh, or upper arm. Rotate sites with each dose. Do not inject into tender, bruised, or scarred skin. Do not mix with insulin or use the same injection site for two medicines at the same time.

Set a weekly reminder. If your weekly schedule must change, pick a new weekly day and keep it consistent thereafter. For practical tips on easing early side effects, see Manage Trulicity Side Effects.

Strengths and Forms

Single-dose, prefilled autoinjector pens are typically available in the following weekly dose strengths:

• 0.75 mg/0.5 mL
• 1.5 mg/0.5 mL
• 3 mg/0.5 mL
• 4.5 mg/0.5 mL

Availability may vary by supply and location. Your prescriber will choose the right starting strength and adjust if needed.

Missed Dose and Timing

If you miss a weekly injection and the next planned dose is at least three days away, take the missed dose as soon as possible. If less than three days remain until your next dose, skip the missed dose and resume the regular schedule. Do not take two doses within three days of each other.

Storage and Travel Basics

Unopened pens are usually stored in a refrigerator. Keep them in the original carton to protect from light. Do not freeze. If a pen has been frozen, do not use it. When labeled guidance allows room-temperature storage for a limited time, keep below the specified maximum temperature and avoid direct heat and sunlight. For travel, pack your pen in a carry-on bag with your prescription label. Consider a small cooler if you expect warm conditions. Use temperature-controlled handling when required.

Keep all medicines out of reach of children and pets. Dispose of expired or unused pens according to local guidance or pharmacy instructions. For supplies and related items, browse Diabetes Care.

Pen Handling and Sharps Disposal

Each pen is single use. Read the Instructions for Use that come with your pen before injecting. General steps include:

• Wash hands, choose an injection site, and clean the skin.
• Remove the cap. Place the base flat on skin.
• Unlock if applicable, then press and hold the button to start.
• Listen for the clicks and wait until the indicator shows the dose is complete.
• Lift the pen from skin. The needle is shielded and not reused.

Place the used pen in an FDA-cleared sharps container. If none is available, use a heavy-duty household container with a tight-fitting, puncture-resistant lid until you can transfer to proper disposal. Do not throw loose pens in household trash or recycling.

Benefits

This medicine supports A1C reduction when combined with diet and exercise. Weekly dosing can be convenient compared with once-daily options. The treatment has a low risk of low blood sugar when used without insulin or sulfonylureas. Some patients with cardiovascular risk factors may receive additional heart-related benefits per approved labeling. Results vary by individual and concomitant therapy.

Side Effects and Safety

Some people describe early nausea with the Trulicity pen, which often improves over time. Common effects may include:

• Nausea or vomiting
• Diarrhea or stomach pain
• Decreased appetite
• Indigestion or bloating
• Fatigue or headache
• Injection site reactions

Serious risks can include pancreatitis, gallbladder problems, kidney issues from dehydration, and severe allergic reactions. There is a boxed warning for risk of thyroid C-cell tumors; avoid use if you or family members have MTC or MEN2. Low blood sugar can occur when this therapy is used with insulin or sulfonylureas. If you experience severe abdominal pain, neck swelling, hoarseness, or trouble breathing, seek urgent care.

Drug Interactions and Cautions

Taking this treatment with insulin or sulfonylureas may increase the chance of hypoglycemia. Because it slows gastric emptying, it can affect how some oral medicines are absorbed; your prescriber may advise timing adjustments for sensitive drugs. Tell your clinician about all medicines, vitamins, and herbal supplements. Use caution if you have a history of pancreatitis, gallbladder disease, or severe gastrointestinal disorders.

What to Expect Over Time

Many people notice early digestive symptoms that tend to lessen as the body adjusts. Blood sugar improvements typically emerge with steady weekly use, alongside nutrition and activity plans prescribed by your clinician. Building a routine helps: use phone reminders, keep a spare pen within storage limits, and track doses on your calendar. For broader comparisons among therapies, browse Types Of Insulin to understand roles across diabetes care.

Compare With Alternatives

Other prescription options may suit different needs. DPP-4 inhibitors are taken by mouth and can be considered when injections are not preferred. You can review Sitagliptin or Sitagliptin Malate to see how mechanisms, dosing, and tolerability compare. Your prescriber will choose the approach that fits your health history and goals.

Pricing and Access

We provide transparent information on the Trulicity price and current availability. Products are fulfilled by licensed partners and Ships from Canada to US. For updates on savings opportunities, see Promotions. If you are comparing cash-pay options, check the listing for the most up-to-date details and bring questions to your clinician.

Two helpful actions: review potential savings compared with local cash-pay options, and compare total costs when choosing multi-pen quantities. If you have insurance, confirm your plan’s coverage and any prior authorization requirements.

Availability and Substitutions

Supply can change. If your strength is temporarily unavailable, a prescriber may suggest an alternative dose or a different class that fits your history. When discussing options, consider clinical fit first and then discuss Dulaglutide cost as part of the plan.

Patient Suitability and Cost-Saving Tips

This therapy may fit adults with type 2 diabetes who need additional glucose control after diet and exercise. It is not right for people with type 1 diabetes, diabetic ketoacidosis, or those with a history of MTC or MEN2. Share any history of pancreatitis, severe stomach problems, or gallbladder disease with your clinician. If you use insulin or a sulfonylurea, ask about strategies to reduce low blood sugar risk.

Smart ways to manage total spend include choosing multi-month supplies when appropriate, setting refill reminders, and aligning prescription renewals to reduce separate fees. If you pay cash, discuss Dulaglutide price without insurance and compare quantities to find the best value for your situation.

Questions to Ask Your Clinician

• Is a weekly GLP-1 right for my A1C target and medical history?
• How should I time other medicines that may be affected by slower stomach emptying?
• What signs suggest pancreatitis or gallbladder problems, and what should I do?
• How can I reduce nausea when starting this medicine?
• If I use insulin or a sulfonylurea, how do I lower hypoglycemia risk?
• What follow-up labs and check-ins should I plan for?

Authoritative Sources

• Manufacturer Prescribing Information
• FDA DailyMed
• Health Canada Drug Product Database

Ready to start? Buy Trulicity pen online with prompt, express shipping and US shipping from Canada. This page is informational and not a substitute for professional medical advice; always follow your prescriber’s instructions.