Please note: a valid prescription is required for all prescription medication.
Clarus® Capsules for Severe Acne
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Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
Price range: $51.10 through $99.07
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Clarus is a prescription isotretinoin capsule used for severe nodular acne. It may help when other treatments do not control breakouts. You can access US delivery from Canada through our platform, including options for isotretinoin capsules without insurance.
What Clarus Is and How It Works
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Clarus® is a Canadian brand of isotretinoin for severe, scarring acne. It is a retinoid that reduces oil production in the skin and may limit inflammation within pores. Over time, this can reduce deep, painful lesions and future flare-ups.
Clarus isotretinoin from Canada is prescription-only and dispensed under strict pregnancy-prevention rules. This medicine is taken by mouth with food. It supports long-term control by addressing the causes of nodular acne at the oil gland level.
Learn more about acne basics in What Is Acne and common care steps in How To Treat Acne.
Who It’s For
This treatment is for severe nodular acne that has not improved with antibiotics and topicals. It is used in teens and adults as directed by a clinician.
Do not use if you are pregnant or may become pregnant. Do not breastfeed while taking it. People with severe liver disease, very high blood lipids, or uncontrolled mental health conditions may need a different approach. Review your full medical history and medications with your prescriber.
For condition context, see our Severe Acne category.
Dosage and Usage
Use exactly as prescribed. The typical plan is once or twice daily with food, for a defined course. Swallow capsules whole with water. Do not crush or open the capsule. Take at the same times each day to support consistency.
Your clinician may order labs to monitor liver enzymes and lipids. Avoid vitamin A supplements during therapy. Use two reliable forms of birth control and follow program requirements throughout treatment and for a period afterward, as instructed on the official label.
Report severe headaches, vision changes, mood changes, stomach pain, or persistent vomiting right away. If unclear on timing, consult your prescriber or pharmacist. You can also read practical acne tips in How To Prevent Acne.
Strengths and Forms
Capsules are the oral form. Commonly available strengths include:
- 10 mg softgel capsules
- 20 mg softgel capsules
- 40 mg softgel capsules
Availability may vary. Some people search for buy isotretinoin Clarus capsules, but a valid prescription is required and supply is pharmacist-dispensed.
Missed Dose and Timing
If you miss a dose, take it when you remember with food. If it is close to your next scheduled dose, skip the missed dose. Do not double up to make up for a missed capsule. Try to choose routine mealtimes to support adherence.
Storage and Travel Basics
Keep capsules in the original container with the label. Store at room temperature away from excess heat, moisture, and direct light. Keep out of reach of children and pets.
For travel, pack enough for the full trip plus a few extra days. Keep the labeled container in your carry-on and bring a copy of your prescription. Do not share this medicine with anyone. Do not donate blood during therapy or for a set period afterward, as instructed by your clinician.
Benefits
This therapy targets oil glands and helps limit pore blockage. Many people see fewer deep lesions and less scarring risk after a full course. Capsules can be easier to integrate into daily routines compared with multi-step topical regimens. Treatment courses are time-limited, which some patients prefer over indefinite topical maintenance alone. Outcomes depend on individual factors and clinician guidance.
Side Effects and Safety
- Dry lips and skin
- Dry eyes or irritation with contact lenses
- Nose dryness or nosebleeds
- Back or joint aches
- Headache
- Temporary changes in triglycerides or liver enzymes
Serious risks include severe birth defects if taken during pregnancy. Other rare but important risks can include mood changes, severe abdominal pain or pancreatitis, vision problems, or signs of pseudotumor cerebri. Stop the medicine and seek urgent care for severe headaches with vision changes, chest pain, trouble breathing, swelling, or allergic reactions.
Drug Interactions and Cautions
Avoid vitamin A supplements. Combining with tetracycline antibiotics may increase the risk of pressure-related headaches; do not take both unless your prescriber directs it. Some hormonal contraceptives can be affected by certain herbs; St. John’s wort may reduce contraceptive effectiveness. Limit alcohol, which can worsen lipid and liver effects. Avoid waxing, aggressive peels, or dermabrasion during treatment and for a period after. Use sun protection due to increased sensitivity.
What to Expect Over Time
Skin dryness often appears early. Breakouts may improve gradually during the course. Some patients notice an initial flare before improvement. Your prescriber may check labs and overall response. Keep a simple skincare routine with gentle cleanser and moisturizer, and use lip balm to manage dryness. Consistent use as directed supports the intended results.
Compare With Alternatives
For milder or maintenance needs, topical options may be considered. Clascoterone cream is a non-retinoid anti-androgen; see Winlevi. A topical phosphodiesterase-4 inhibitor may help plaque psoriasis and some off-face concerns; review Zoryve with your clinician. Your prescriber will decide which option fits your condition and history.
Pricing and Access
We list Clarus isotretinoin price with clear options when available. You get Canadian pricing with US shipping from Canada and a secure checkout experience. Final amounts depend on your prescription and selected quantity.
Looking for ways to save? Check our seasonal Promotions page for current offers where available. For broader dermatology options, browse our Dermatology category.
Availability and Substitutions
Supply can vary by strength and pack size. If an item is out of stock, your prescriber may recommend an alternative or adjusted plan. We update listings to reflect Clarus isotretinoin US shipping status when possible. We do not guarantee specific dates for availability.
Patient Suitability and Cost-Saving Tips
This therapy may suit patients with scarring nodular acne who tried other options without success. It is not appropriate during pregnancy or while breastfeeding. People with certain liver, lipid, or mental health conditions need careful evaluation.
To manage costs, ask your prescriber about multi-month fills when appropriate, which may reduce per-unit pricing. Set refill reminders so you do not miss doses during a course. If your plan allows, compare pharmacy options for the best overall value. For ongoing supply, we can support a Clarus isotretinoin refill when your prescriber authorizes it. Our checkout uses encryption to protect your information.
Questions to Ask Your Clinician
- Course length and goals: What outcomes are realistic for my case?
- Monitoring plan: Which labs and how often?
- Birth control: Which methods are recommended with this medicine?
- Side effect management: How to handle dryness, headaches, or mood changes?
- Skincare routine: Which cleansers and moisturizers are suitable?
- Activity and procedures: Any limits on sports or cosmetic treatments?
- Follow-up: When should I check in about progress or concerns?
Authoritative Sources
DailyMed Isotretinoin LabelingHealth Canada Drug Product DatabaseWhat Helps With Acne Scars
Ready to proceed? You can order Clarus isotretinoin online with prompt, express shipping, with temperature-controlled handling when required. This page is informational and not a substitute for medical advice; always follow your clinician’s instructions and the official label.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Why are pregnancy tests required before and during Clarus treatment?
Clarus can cause serious birth defects, so pregnancy must be avoided. Frequent pregnancy testing ensures safety throughout treatment.
Can Clarus be used for mild acne?
No, it is reserved for severe, cystic acne or cases unresponsive to other treatments. Milder cases can often be treated with topical medications.
What happens if I miss a dose?
Take it as soon as you remember, unless it’s close to your next dose. Do not double up to make up for a missed capsule.
Is it normal for acne to get worse at first?
Yes, flare-ups are common in the early weeks. This usually improves as treatment continues.
Can I wear makeup while using Clarus?
Yes, but choose non-comedogenic (non-pore-clogging) products and ensure your skin remains moisturized.
What makes Clarus different from other acne treatments?
Clarus is an oral isotretinoin capsule used for severe nodular acne that has not responded to other therapies. It works within oil glands to reduce sebum and limit pore blockage. This approach targets the root causes of deep lesions, which topical medicines often cannot reach. Treatment is time-limited and monitored with labs. Your clinician will determine if this option is appropriate based on your history, exam, and prior treatments.
How long is a typical treatment course?
Courses are time-limited and often last several months, but exact duration varies by individual needs and prescriber direction. The medicine is usually taken with food, once or twice daily. Your clinician will outline a schedule and any needed lab monitoring. Do not change your dose or stop abruptly without guidance. If you miss a dose, take it when you remember unless it is close to the next scheduled capsule.
Can I take supplements or other medicines with isotretinoin?
Avoid vitamin A supplements while taking isotretinoin, as this can increase side effects. Tetracycline antibiotics are generally avoided due to risk of increased intracranial pressure. Alcohol may raise triglycerides and strain the liver, so use caution. Tell your prescriber about all medicines, herbs, and over-the-counter products, including St. John’s wort, which may affect contraceptive effectiveness. Your clinician can review your full list for safety.
What side effects should I watch for?
Common effects include dry lips and skin, dry eyes, nose dryness, headache, and temporary changes in triglycerides or liver enzymes. Seek urgent care for severe headaches with vision changes, chest pain, shortness of breath, severe abdominal pain, mood changes with self-harm thoughts, or signs of an allergic reaction. Report any pregnancy exposure immediately. Your clinician will guide supportive care for dryness and other manageable effects.
Can I have cosmetic procedures during treatment?
Waxing, dermabrasion, and aggressive chemical peels are generally avoided during isotretinoin therapy and for a period afterward due to the risk of scarring and skin injury. Discuss timing with your dermatologist before scheduling procedures. Use daily sunscreen and gentle skincare during treatment. If you are unsure about a product or service, ask your clinician for guidance before proceeding.
How should I store the capsules at home and while traveling?
Keep capsules in their original labeled container at room temperature. Protect from heat, moisture, and light. Store out of reach of children and pets. For travel, pack the medicine in your carry-on and bring a copy of your prescription. Keep enough supply for your trip plus a few extra days. Do not share this prescription with anyone, and do not donate blood during therapy or shortly after.
What if Clarus is not available in my strength?
Supply can vary by strength and package size. If your strength is unavailable, your prescriber may recommend a different strength, an alternative acne therapy, or a later fill date based on your needs. We update listings as supply information changes, but we do not guarantee restock timelines. Your clinician can advise on safe substitutions aligned with your treatment plan.
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