Combivir® Tablets for HIV

Combivir is a prescription HIV medicine combining lamivudine and zidovudine. It is used with other antiretrovirals to help lower viral load and support immune recovery. This page explains use, safety, and how you can access it with US delivery from Canada, including options if you’re paying without insurance.

What Combivir Is and How It Works

Combivir® contains lamivudine and zidovudine, two nucleoside reverse transcriptase inhibitors. These medicines block reverse transcriptase, an enzyme HIV needs to replicate. Taken with a compatible regimen, the treatment can reduce viral load and support CD4 counts over time.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine is usually part of a combination plan chosen by your prescriber. It may be paired with an integrase inhibitor or another class to form a complete regimen. Using it consistently as directed supports long-term control of HIV.

Who It’s For

This therapy is indicated as part of combination treatment for people living with HIV-1. It can be appropriate for adults and certain adolescents when combined with other active agents. Your prescriber will select a complete plan based on your history, lab results, and potential resistance.

People with known hypersensitivity to lamivudine or zidovudine should not use it. Those with significant anemia, neutropenia, or advanced liver disease may need different options. If you also have hepatitis B, stopping lamivudine can cause HBV flare. Discuss pregnancy and breastfeeding plans with your healthcare professional. For broader context on the condition, see Hiv and review symptom basics in Hiv Aids Symptoms.

Dosage and Usage

Standard adult dosing is one tablet taken twice daily, with or without food. Swallow tablets whole with water. If your prescriber has tailored your schedule, follow those instructions and defer to the official label for specifics. Avoid taking this therapy with other medicines that also contain lamivudine or zidovudine.

People with kidney or liver problems may require individualized plans; your care team will guide those decisions. Take doses at the same times each day to support steady levels. The phrase Lamivudine zidovudine 150/300 mg tablets refers to the fixed-dose strength used in many adults; do not alter or split the tablet unless your prescriber advises.

Strengths and Forms

This treatment is supplied as oral tablets. Availability can vary by pharmacy and manufacturer.

• Combivir tablets 150 mg/300 mg

If your regimen requires a different component ratio, your clinician may prescribe the single agents separately.

Missed Dose and Timing

If you miss a dose and remember soon after, take it as soon as possible. If it is close to your next scheduled time, skip the missed dose and resume your regular schedule. Do not double doses. If vomiting occurs shortly after taking a tablet, check the official label and contact your prescriber for guidance.

Storage and Travel Basics

Store tablets at room temperature in the original, tightly closed container. Keep away from excess heat, moisture, and direct light. Use child-resistant caps and store out of reach of children and pets. When traveling, carry your medicine in a labeled container, keep it in your hand luggage, and bring a copy of your prescription. A simple pill organizer may help maintain your schedule across time zones. If flying, allow extra time for security screening and keep a medication list handy.

Benefits

As part of a complete plan, this combination can help reduce viral load and support immune recovery. A fixed-dose tablet may simplify routines versus taking the two components separately. Consistent use can support adherence, which is important for long-term control. Your clinician will pair it with other agents to create an effective regimen tailored to your needs.

Side Effects and Safety

• Common: nausea, headache, fatigue
• Sometimes: insomnia, rash, diarrhea, cough
• Lab changes: anemia or neutropenia with zidovudine

Serious but less common risks include lactic acidosis, hepatomegaly with steatosis, pancreatitis (notably in pediatrics), myopathy, and hypersensitivity. Report symptoms like unusual tiredness, shortness of breath, rapid breathing, severe abdominal pain, jaundice, or persistent muscle weakness. Your care team may monitor blood counts and liver function, especially early in therapy and when adjusting other medicines.

Drug Interactions and Cautions

Tell your prescriber about all medicines and supplements. Avoid combining with other lamivudine-containing products, or with drugs that significantly overlap zidovudine’s toxicity, such as certain bone marrow–suppressive agents. Sorbitol can decrease lamivudine levels. Ribavirin and interferon may increase the risk of hematologic toxicity. Methadone can affect zidovudine levels; monitoring may be needed. Alcohol can stress the liver, so discuss intake with your clinician. If you need hepatitis B therapy, your prescriber may consider dedicated options; see our antiviral category Antivirals for context.

What to Expect Over Time

With steady use and a compatible regimen, viral load may decline and CD4 counts may improve. Many people feel no immediate changes day to day; control is measured by lab results over time. Your clinician may schedule regular blood tests to track response and safety. If you experience side effects, do not stop on your own. Contact your prescriber to discuss options, which may include supportive care or switching to an alternative regimen if appropriate. For testing background, see Types Of Hiv Tests. For prevention education, review How Can You Get Hiv.

Compare With Alternatives

Some people may use an integrase-based single-tablet regimen. For example, Triumeq 600mg 50mg 300mg combines dolutegravir, abacavir, and lamivudine; HLA-B*5701 testing is required due to abacavir hypersensitivity risk. Others may use an NNRTI-based plan; Pifeltro (doravirine) is paired with compatible agents for a complete regimen. Your clinician will choose based on resistance, comorbidities, and treatment goals.

Pricing and Access

We make it straightforward to compare cash-pay options and check availability. You can review the Canada listing to confirm sourcing and see current selection. For savings updates, visit our Promotions page. We provide US options with Canadian pharmacy pricing and fulfilment that Ships from Canada to US. Check typical self-pay details and talk with your prescriber about multi-month refills if appropriate.

If you want to compare the Combivir price, use the product page tools to see current ranges and availability. To begin a request, you can Order lamivudine zidovudine online once your prescription is ready. No timelines are promised; your order proceeds after verification with your prescriber.

Availability and Substitutions

Stock can change, and formulations may vary by manufacturer. If this tablet is not available, a prescriber may recommend an alternative regimen using equivalent components or another fixed-dose combination. When appropriate, you may be able to Buy generic lamivudine zidovudine 150/300 if your clinician approves and your pharmacy has it in stock. Never switch products without clinical guidance.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who need an NRTI backbone with compatible agents and have no contraindications to either component. Those with advanced anemia, significant neutropenia, or severe liver disease may need different choices. If coinfected with HBV, do not stop lamivudine without medical oversight due to the risk of hepatitis flare.

For budgeting, consider multi-month fills when your prescriber allows. Set calendar reminders, align refills with clinic visits, and keep a small travel reserve approved by your clinician. If comparing options by cash-pay, you can review the Lamivudine zidovudine price across comparable products in our Hiv condition area to understand ranges, not as medical advice.

Questions to Ask Your Clinician

• Regimen fit: How does this combination pair with my other HIV medicines?
• Safety labs: How often will you check blood counts and liver enzymes?
• Anemia risk: What symptoms should I watch for with zidovudine exposure?
• HBV status: Do I need hepatitis B testing or added therapy before starting?
• Pregnancy plans: Is this option appropriate if I become pregnant?
• Drug conflicts: Which medicines, supplements, or sugar alcohols should I avoid?
• Plan changes: When would you consider switching to a different backbone?

Authoritative Sources

FDA DailyMed

ViiV Healthcare

Health Canada Drug Product Database

Buy Combivir online at Border Free Health with US shipping from Canada and prompt, express shipping with temperature-controlled handling when required. This content is educational and not a substitute for professional medical advice. Always follow your prescriber’s instructions and the official label.