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Intelence® Tablets for HIV-1
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Intelence is a non-nucleoside reverse transcriptase inhibitor used with other antiretrovirals to treat HIV-1. This page explains uses, dosing basics, and ways to access Canadian pricing with US delivery from Canada. Many visitors also check Intelence price without insurance and compare treatment options.
What Intelence Is and How It Works
Intelence® contains etravirine, an NNRTI that helps block HIV-1 reverse transcriptase. By reducing this enzyme’s activity, the therapy helps lower viral replication when used in combination regimens. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This medicine is typically used in treatment-experienced adults and adolescents as part of a complete, suppressive HIV regimen. It is taken after a meal to support absorption. If you are exploring options like Etravirine tablets for sale, review the official label and discuss the full regimen plan with your clinician. Learn more about the condition on our Hiv page and see related topics such as HIV Tests and HIV Symptoms.
Who It’s For
This treatment is indicated for HIV-1 infection in adults and certain pediatric patients when used with other antiretrovirals. It is commonly considered for people with prior treatment exposure who need an NNRTI option guided by resistance testing.
People with a known hypersensitivity to etravirine should avoid it. Those with a history of severe skin reactions, significant liver disease, or hepatitis coinfection need careful evaluation. Always confirm the full regimen with a healthcare professional.
Dosage and Usage
Standard schedules follow the approved label. The tablets are taken twice daily after a meal. Food matters for absorption; avoid dosing on an empty stomach. Swallow whole with water. If swallowing is difficult, the tablet may be dispersed in water according to label directions and consumed promptly, followed by additional water to ensure the full dose is taken.
Use as part of a complete regimen. Do not change doses or stop therapy without guidance. Skipping doses can lead to resistance and reduced effectiveness of the overall plan. For foundational HIV care resources, see our article on Biktarvy Guide and awareness content like HIV Testing Day.
Strengths and Forms
The product is supplied as film-coated tablets. The commonly referenced strength is 200 mg. Availability and packaging may vary by manufacturer and market.
Missed Dose and Timing
If a dose is missed, general guidance is to take it as soon as remembered with food, unless it is close to the next dose. If the next dose is near, skip the missed dose and resume the regular schedule. Do not double up to compensate. Follow the official patient information for precise instructions.
Storage and Travel Basics
Store at room temperature, away from excessive heat and moisture. Keep tablets in the original, tightly closed container and out of reach of children. Do not store in the bathroom. When traveling, carry medicines in hand luggage with original labels. Bring a copy of your prescription and a medication list for security and customs checks. If crossing time zones, maintain the twice-daily rhythm using local time. For country-of-origin details, see Canada. As a micro trust cue, checkout uses encrypted processing.
Benefits
As part of a complete antiretroviral regimen, this NNRTI can help reduce viral load and maintain suppression when paired with active agents. The tablet can be dispersed in water if needed, providing an option for those who have difficulty swallowing. Taking it with food supports consistent absorption and routine adherence.
Side Effects and Safety
- Common effects: rash, nausea, diarrhea, headache
- Less common: abdominal discomfort, fatigue, insomnia
- Liver-related lab changes have been reported
Serious skin reactions, including hypersensitivity reactions and rare severe rashes, can occur. Seek urgent care if you notice blistering, mucosal involvement, fever, or systemic symptoms with a rash. People with hepatitis or other liver conditions may require closer monitoring. As with many antiretrovirals, immune reconstitution events can occur after starting therapy. Review the full safety profile on the official label and with your clinician.
Drug Interactions and Cautions
Etravirine interacts with pathways including CYP3A, CYP2C9, and CYP2C19. Strong enzyme inducers may reduce levels and are typically avoided. Examples include certain anticonvulsants (such as carbamazepine, phenobarbital, phenytoin), rifamycins, and herbal products like St. John’s wort. Some antiretrovirals are not recommended in combination. Warfarin and other narrow-therapeutic-index agents may require monitoring. Hormonal contraceptive effectiveness can change with enzyme induction.
Alcohol, illicit substances, and over-the-counter products may also interact. Share a complete medication list with your healthcare professional before starting or stopping any treatment. For background reading, see Metformin And Hiv for research context, and Aptivus For Hiv for a different class option discussed by experts.
What to Expect Over Time
With consistent use as part of a complete regimen, many patients see gradual reductions in viral load and improvements in CD4 counts. Effects vary based on resistance profile, adherence, and the overall combination. Some side effects appear early and may lessen. Skin reactions require careful monitoring throughout therapy. Maintaining regular lab checks helps track progress and safety.
Adherence remains essential for durable suppression. Align dosing with meals and daily routines, and set reminders to support consistency. Discuss any challenges with your clinician promptly to avoid interruptions.
Compare With Alternatives
Within the NNRTI class, doravirine is an option; see Pifeltro for details. In select, treatment-experienced scenarios, a protease inhibitor such as tipranavir may be considered under specialist guidance. Your clinician will base choices on resistance testing, prior exposure, and tolerability.
Pricing and Access
Many patients look for Canadian pricing etravirine to manage out-of-pocket spend. You can review Intelence 200 mg tablet price information on our product page and compare options with your care team. Some shoppers also check Intelence cash price listings and evaluate combination therapy costs across agents. We provide transparent details so you can plan refills and budget effectively.
Border Free Health offers US shipping from Canada with prescription verification. If you are seeking savings, browse current offers on our Promotions page when available. For broader therapy categories, explore Antivirals and condition resources linked above.
Availability and Substitutions
Supply can vary. If a particular pack size is unavailable, a prescriber may recommend a suitable alternative in the same class or a different class based on resistance and interaction checks. For access questions across borders, note that Etravirine ships to US when dispensed through our partner network. We do not provide restock dates; your care team can suggest interim options if needed.
Patient Suitability and Cost-Saving Tips
Good candidates are people with HIV-1 who need an NNRTI in a multi-drug regimen informed by resistance testing. Those with prior severe rash to similar agents or significant hepatic impairment may not be appropriate. Before starting, review all medicines, including supplements and contraceptives, for interaction risks.
- Multi-month fills: request longer supplies when clinically appropriate
- Aligned refills: coordinate refills across your regimen
- Budget planning: compare Canadian pricing and cash-pay options
- Reminders: set alarms tied to meals for steady adherence
- Travel prep: pack extra doses and carry prescriptions
If you plan to Buy etravirine 200 mg later, ask your clinician about resistance testing, food requirements, and your current combination. These steps help reduce changes mid-therapy and support stable suppression.
Questions to Ask Your Clinician
- Is my current resistance profile appropriate for an NNRTI in this class?
- Which companion antiretrovirals best match my history and lab results?
- What should I do if I experience a rash or new symptoms?
- How should I handle a missed dose relative to my next scheduled dose?
- Are there interactions with my anticonvulsants, rifamycins, or supplements?
- What lab monitoring schedule should I follow after starting therapy?
Authoritative Sources
See official information for full indications, dosing, and safety details:
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What is Intelence used for?
Intelence (etravirine) is an antiretroviral medication used in combination with other drugs to treat HIV-1 infection in adults and children. It belongs to the class of drugs called non-nucleoside reverse transcriptase inhibitors (NNRTIs), which help block the replication of HIV. Intelence is typically prescribed when resistance to other NNRTIs has developed. While it does not cure HIV or AIDS, it helps reduce the viral load and maintain immune system function.
How does Intelence work in HIV treatment?
Intelence works by binding to the reverse transcriptase enzyme of the HIV, interfering with its ability to replicate. Doing this reduces the number of active viruses in the body and helps the immune system function more effectively. This mechanism is particularly beneficial for patients who have previously failed other NNRTI-based therapies. Effective viral suppression also reduces the risk of HIV-related complications and transmission.
How should I take Intelence?
Intelence is usually taken twice daily after meals to improve absorption. The tablets should be swallowed whole with liquid, but if swallowing is difficult, they can be dispersed in water and consumed immediately. It’s essential to take the medication consistently at the exact time each day to maintain stable drug levels. Skipping doses or inconsistent intake may lead to drug resistance and treatment failure.
What precautions should I take while using Intelence?
Inform your doctor if you have liver disease, particularly hepatitis B or C, as this may affect your treatment. Intelence may interact with several medications, including antiepileptics, antifungals, and other HIV drugs, so a complete medication review is necessary. Do not use Intelence as monotherapy; it must be part of a combination regimen. Women who are pregnant or breastfeeding should consult their doctor due to limited data on safety in these populations.
What are the common side effects of Intelence?
Side effects may include rash, nausea, diarrhea, and fatigue. Although rare, severe skin reactions, such as Stevens-Johnson syndrome, have been reported and require immediate medical attention. Changes in liver enzymes and lipid levels may also occur, requiring regular monitoring. Always report new or worsening symptoms to your healthcare provider promptly.
How should Intelence be taken with food?
This medicine should be taken after a meal to support absorption and consistent levels. A light snack may not be enough; a balanced meal is preferred. Swallow tablets whole with water. If swallowing is difficult, the tablet may be dispersed in water as directed in the official patient information and consumed immediately, followed by additional water. Do not take it on an empty stomach. Keep the schedule steady, and align doses with regular meals to help adherence.
Can the tablet be dispersed in water?
Yes. If you have trouble swallowing, the tablet can be dispersed in water according to label directions. Stir the mixture until the tablet is evenly dispersed, drink it immediately, and then rinse the glass several times with water to ensure the full dose is taken. Do not chew crushed pieces. Always take it after a meal, even when using the dispersion method, to support absorption.
What are the most common side effects?
Common effects include rash, nausea, diarrhea, and headache. Some people report stomach discomfort or fatigue. Most effects are mild to moderate, but serious skin reactions can occur. If you notice blistering, mucosal involvement, fever, or a spreading rash, seek urgent medical care. Your clinician may monitor liver function and other labs, especially at the start of therapy or when other antiretrovirals are added to the regimen.
Which medicines interact with etravirine?
Interactions may occur with strong enzyme inducers, such as carbamazepine, phenobarbital, phenytoin, rifampin, rifapentine, and St. John’s wort. Some antiretrovirals are not recommended alongside this NNRTI. Warfarin and other narrow-therapeutic-index agents may require closer monitoring. Provide a full list of prescription drugs, OTC products, and supplements to your healthcare professional before starting or stopping any therapy.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember with food, unless it is close to the time for your next dose. If the next dose is near, skip the missed dose and return to your usual schedule. Do not double up. Consistent dosing helps reduce the risk of resistance. For individualized guidance, confirm the official label’s recommendations with your prescriber.
Is this treatment suitable during pregnancy or breastfeeding?
Suitability depends on clinical circumstances. Discuss pregnancy plans or breastfeeding with your clinician before starting therapy. They will consider available safety data, your viral load goals, and the rest of your regimen. Decisions may involve adjusting companion medicines to maintain suppression while managing potential risks. Follow professional advice and official guidance for perinatal HIV management.
How long before I see changes in viral load?
Response timing varies. Many patients begin to see qualitative improvements over the initial weeks as part of a suppressive combination, but specific timelines differ based on resistance, adherence, and the overall regimen. Regular lab checks are used to monitor progress. Keep doses tied to meals and discuss any side effects promptly so your healthcare professional can support adherence and optimize your plan.
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