Nifedipine Extended-Release Tablets for Hypertension and Angina

This calcium channel blocker treats high blood pressure and chronic or vasospastic angina. Nifedipine medication for high blood pressure can also help reduce chest pain episodes. This page explains how the treatment works, how to use it safely, and how to arrange US shipping from Canada with potential savings without insurance.

What Nifedipine Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

The medicine belongs to the dihydropyridine class of calcium channel blockers. It relaxes vascular smooth muscle by inhibiting L-type calcium channels, which lowers peripheral resistance and reduces blood pressure. In angina, it can improve coronary blood flow and decrease myocardial oxygen demand, helping reduce symptoms.

Known brands include Adalat®. For ongoing blood pressure control, extended-release tablets are typically preferred over immediate-release forms. Short-acting nifedipine is not used for hypertensive emergencies.

Learn more about angina patterns in our overview of Angina Symptoms.

Who It’s For

This therapy is used in adults for hypertension and for chronic stable or vasospastic angina, as directed by a clinician. It is not intended for acute hypertensive crises or for immediate relief of chest pain. People with very low blood pressure, significant aortic stenosis, or cardiogenic shock should not use it. Those with heart failure, liver impairment, or gastrointestinal narrowing should discuss suitability and monitoring with a healthcare professional.

Related condition pages: Hypertension and Angina.

Dosage and Usage

Follow the directions on the prescription label and the official patient information. Extended-release tablets are commonly taken once daily at the same time each day. Swallow tablets whole; do not crush, chew, or split. Take consistently with regard to meals per your specific product’s instructions. A nonabsorbable shell may appear in stool for certain tablet designs; this is expected.

Nifedipine 24 hr tablet references a prolonged-release schedule; the clinician decides the exact regimen. Do not make any changes without medical guidance. Keep an updated list of all medicines and bring it to visits.

For broader cardiovascular background, see our Cardiovascular collection.

Strengths and Forms

Availability may vary by partner pharmacy and country of origin. Commonly supplied presentations include:

• Extended-release tablets: 30 mg, 60 mg, 90 mg strengths
• Immediate-release capsules: strengths vary by market and use case

Labels differ by manufacturer. Many patients use once-daily controlled-release tablets for maintenance therapy. Some regions carry brand-label products such as Adalat® in similar strengths. For specific questions about available presentations, consult the dispensing pharmacy.

Nifedipine 60 mg extended release is a typical maintenance strength, though the prescriber determines the right dose based on individual response.

Missed Dose and Timing

If a scheduled dose is missed, take it when remembered unless it is close to the next scheduled time. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double up. Keeping a simple daily routine and using reminders can help maintain consistent use over the long term.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excess moisture and direct light, and out of reach of children and pets. Keep medicine in the original labeled container with the safety cap secured. When traveling, carry the prescription-labeled bottle in a carry-on bag. Bring a copy of the prescription or a medication list for security checks. Avoid leaving the treatment in a hot car or near heaters. If any tablets are damaged or discolored, consult the pharmacist before use.

Benefits

As a calcium channel blocker, this medicine can lower blood pressure and reduce the frequency of angina episodes when used as prescribed. Once-daily extended-release tablets support routine adherence. Generic options may help reduce out-of-pocket expenses compared with brand-only equivalents. Patients often appreciate the steady blood pressure control that can fit into daily habits.

Side Effects and Safety

• Headache, flushing, or dizziness
• Swelling of ankles or feet
• Palpitations or fast heartbeat
• Fatigue or weakness
• Nausea or stomach discomfort
• Constipation
• Gum tenderness or overgrowth

Serious effects are less common but can include significant low blood pressure, fainting, or worsening angina shortly after starting or increasing the dose. Rarely, myocardial infarction has been reported, typically in high-risk settings. Liver enzyme elevations and hypersensitivity reactions may occur. Tablet retention or obstruction has been reported with certain extended-release designs in patients with severe gastrointestinal narrowing. Seek urgent care for severe chest pain, signs of allergic reaction, or concerning symptoms.

For a class comparison resource, see Verapamil Uses.

Drug Interactions and Cautions

Nifedipine is metabolized by CYP3A4. Strong inhibitors (for example, ketoconazole, clarithromycin, ritonavir) can increase exposure. Strong inducers (such as rifampin or certain anticonvulsants) can reduce effectiveness. Avoid grapefruit or grapefruit juice, which can significantly raise levels. Combined use with other blood pressure medicines, nitrates, or alcohol can enhance hypotensive effects. St. John’s wort may reduce levels. Some statins and immunosuppressants are sensitive to CYP3A4 interactions; clinicians may review dose limits or alternatives.

Those who are pregnant, breastfeeding, or planning procedures should discuss risks and benefits. Do not use for acute chest pain relief. For emergency heart symptoms, learn the basics in Acute Coronary Syndrome.

What to Expect Over Time

Blood pressure reduction typically develops with regular use. Angina frequency may lessen as the dose and schedule are optimized under medical supervision. Tolerability often improves after the first days as headaches and flushing decrease for many patients. Keep a log of readings and symptoms and bring it to appointments. Adherence and consistent timing are important for steady control.

Compare With Alternatives

Other options for blood pressure and angina management include different calcium channel blockers, beta blockers, nitrates, and combination therapies. Some patients remain on the same class while others combine classes to reach targets. For a branded controlled-release option, see Adalat XL. For beta-blocker therapy used in many hypertension and angina plans, consider Atenolol. Your prescriber selects a regimen based on conditions, other medicines, and goals.

Pricing and Access

Borderfreehealth lists current options with Canadian pricing and clear cash-pay details. Nifedipine price online is shown per product page so you can compare formulations before checkout. Orders are fulfilled by licensed partners and Ships from Canada to US. Our encrypted checkout protects personal and payment information.

To see available fills and timing, open the product tab and review the selection. Savings vary by formulation and supply length. If your prescriber supports it, a longer supply may reduce per-tablet costs and cut trips to the pharmacy.

Availability and Substitutions

Supply can vary by manufacturer, strength, and formulation. If an item is temporarily unavailable, a prescriber may suggest a therapeutically appropriate alternative or a different presentation. Order Nifedipine online only with a valid prescription, and the pharmacy will verify details before dispensing. When substitution is necessary, the team coordinates with the prescriber for authorization.

Patient Suitability and Cost-Saving Tips

Good candidates are adults with hypertension or chronic angina who need a once-daily option and do not have contraindications such as severe hypotension or shock. Those with significant hepatic impairment or gastrointestinal narrowing require careful assessment. Keep the same brand or generic version once stable, if possible, to minimize variability.

• Ask about a 90‑day fill to reduce refill steps
• Set refill reminders before the last week
• Compare ER versus IR options for convenience
• Use the same manufacturer when feasible
• Bring an updated medication list to visits

For broad education on related therapies, see our background on Angina and long-form cardiovascular guides.

Questions to Ask Your Clinician

• Is an extended-release tablet appropriate for my condition?
• Which interactions should I watch for with my current medicines?
• What signs mean I should seek urgent care?
• How should I coordinate this with nitrates or beta blockers?
• Can I switch manufacturers without a new visit?
• What monitoring schedule fits my risk factors?

Authoritative Sources

FDA DailyMed official labeling database

Health Canada Drug Product Database

Manufacturer Information

Ready to proceed? Add to cart for prompt, express shipping with US delivery from Canada, then complete checkout to start fulfilment. This information is not a substitute for professional medical advice; always follow your prescriber’s guidance.