Pregnyl® Injection for Infertility

This prescription medicine contains human chorionic gonadotropin used in fertility care and certain hormone disorders. It supports ovulation in women and testosterone production in males with pituitary-related deficiency. This page explains how it works, safety basics, and how you can review options without insurance, with US shipping from Canada.

What Pregnyl Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Pregnyl® is a brand of human chorionic gonadotropin. This medicine acts like luteinizing hormone. In women undergoing assisted reproduction or ovulation induction, it helps the final maturation of follicles and triggers ovulation. In males with certain pituitary causes of hypogonadism, it stimulates Leydig cells to produce testosterone. In prepubertal boys with specific cases of undescended testicle, it may assist testicular descent when appropriate.

HCG binds to LH receptors on ovarian theca and granulosa cells or testicular Leydig cells. That receptor activity supports ovulation and progesterone production in women and testosterone production in males. Your care team may combine this therapy with other gonadotropins as part of a treatment plan.

Who It’s For

This treatment may be prescribed for:

• Ovulation induction in appropriately selected women
• Hypogonadotropic hypogonadism in males
• Certain cases of cryptorchidism in prepubertal boys

It is not for weight loss or performance enhancement. People with hormone-sensitive tumors, prostate cancer, or allergies to any component should not use it. Women with primary ovarian failure, uncontrolled thyroid or adrenal disease, or ovarian cysts not due to polycystic ovaries may not be candidates. Discuss your medical history, including clotting risks and migraines, with your clinician.

Learn more about indications and care pathways in Infertility, Hypogonadism, and Undescended Testicle resources.

Dosage and Usage

Use exactly as directed by your prescriber. Treatment plans vary by indication and by response to prior follicle stimulation or baseline hormone status. For ovulation induction, a single timed dose often follows ovarian stimulation under monitoring. For male hypogonadism, dosing is typically scheduled multiple times per week over weeks to months. For cryptorchidism, courses are time limited and age specific. Administration may be subcutaneous or a pregnyl intramuscular injection, depending on clinical guidance.

This medicine is supplied as a powder with a diluent. A healthcare professional will show you how to reconstitute and give each dose. Wash hands, use sterile supplies, rotate injection sites, and follow the mixing steps provided with the product. Do not use if the solution is cloudy or contains particles after mixing. Never share syringes or needles.

If you are new to gonadotropin therapy, review our overview article for additional context: Pregnyluses Dosage Side Effects.

Strengths and Forms

Products and packs can vary by country and supplier. Common presentations include lyophilized powder vials with sterile solvent:

• Single-use vial labeled 5000 IU with supplied diluent
• Single-use vial labeled pregnyl 10000 iu with supplied diluent

Availability of specific pack sizes may change. Your prescription will specify the strength and quantity.

Missed Dose and Timing

Timing matters. For ovulation triggering, contact your clinic if you miss the scheduled window. Do not self-adjust timing without guidance, because monitoring aligns the trigger with follicle development. For ongoing male therapy, if you miss a dose of an hcg pregnyl injection, take it when remembered unless it is close to the next scheduled dose. When unsure, ask your prescriber or pharmacist.

Storage and Travel Basics

Follow the storage instructions provided with your specific kit. Unopened powder vials are usually kept at controlled room temperature away from light. After reconstitution, stability depends on the product and diluent; many preparations are intended for immediate use. Do not freeze. Keep all supplies out of reach of children.

For trips, carry your pregnyl vial, diluent, syringes, and prescriptions in your hand luggage. Use a protective case. Bring a copy of your prescription. If your regimen requires refrigeration after mixing, use a small insulated container and ice packs as instructed. Airport screening agents are familiar with medical supplies; allow extra time for security checks. Our checkout uses encrypted technology to protect your information.

See our broader endocrine category for related guidance: Endocrine Thyroid and country-specific sourcing on Country Of Origin Canada.

Pen Handling and Sharps Disposal

This therapy is supplied as vials, not a prefilled pen. Use new sterile needles and syringes as taught. Dispose of used needles and syringes in an FDA-cleared sharps container. If you do not have one, use a heavy-duty plastic household container with a tight lid, then follow local rules for disposal.

Benefits

As part of a monitored plan, this treatment helps complete follicular maturation and trigger ovulation. For males with certain pituitary deficiencies, it can support endogenous testosterone production. In select prepubertal boys, it may aid testicular descent when clinically appropriate. Many patients appreciate that the therapy aligns with established reproductive protocols and can be coordinated with ultrasound and lab monitoring.

Side Effects and Safety

• Injection site pain or redness
• Headache, fatigue, irritability
• Nausea or abdominal discomfort
• Fluid retention or swelling
• Mood changes or restlessness

Women may experience ovarian enlargement or ovarian hyperstimulation syndrome. Multiple pregnancy can occur. Males may notice acne, breast tenderness, or changes related to increased androgens. Rare but serious events include blood clots, severe abdominal pain or swelling, shortness of breath, vision changes, or symptoms of early puberty in boys. Seek urgent care if you develop severe or unusual symptoms. This medicine may increase the risk of hypoglycemia when used with insulin or sulfonylureas in people with diabetes; monitor as directed.

Drug Interactions and Cautions

Tell your prescriber about all medicines, vitamins, and supplements you use. Interactions can occur with other reproductive hormones, and care teams coordinate doses to avoid overlapping effects. Report any history of hormone-sensitive cancers, unexplained uterine bleeding, ovarian cysts not due to polycystic ovaries, prostate enlargement or cancer, or thromboembolic disease. Your clinician may check thyroid and adrenal function before and during treatment. Do not use during pregnancy for ovulation induction; stop once pregnancy is confirmed and follow clinic instructions.

For added context on endocrine conditions, you can review Understanding Hypothyroidism.

What to Expect Over Time

Expect close monitoring from your clinic. In fertility cycles, this therapy is usually timed after follicle growth verified by ultrasound and estradiol testing. Your team will advise on intercourse or retrieval timing. In male hypogonadism, clinicians monitor testosterone, testicular size, and sometimes semen parameters over time. Results vary. Adherence to dosing and appointments, plus open communication about side effects, can help your team adjust your plan.

Compare With Alternatives

Other options exist within the same treatment pathway. Choriogonadotropin alfa is a recombinant form used as a trigger in many programs. Menotropins or urofollitropin are often combined with an hCG trigger. Your prescriber will select the agent that fits your protocol, monitoring plan, and access. For broader therapy pathways and education, see our Infertility category and this overview of related topics, including PCOS care strategies: Medication For PCOS.

Pricing and Access

You can view options and buy pregnyl online with transparent cash-pay details. Canadian pricing is often competitive compared with typical U.S. rates. We arrange fulfilment through licensed partners with Ships from Canada to US. Check the product page for current availability. If you are looking for coupons, see our latest updates on Promotions.

For those receiving anesthesia during procedures such as oocyte retrieval, your clinic may supply medications. If you wish to learn about an anesthetic agent sometimes used in procedural settings, visit Propofol. Always follow your clinic’s protocol.

Availability and Substitutions

Supply can vary. If this brand is unavailable, a prescriber may recommend a comparable alternative within the same class or a recombinant option. Your care team will review suitability and local requirements before any change. We cannot guarantee restock timing.

Patient Suitability and Cost-Saving Tips

Ideal candidates are patients under active care with clear indications and monitoring plans. People with contraindications listed above may not be suitable. Cost-conscious steps include discussing multi-month plans when appropriate, asking your clinic about coordinated lab schedules, and setting refill reminders to avoid last-minute purchases. Consider travel-safe packing to protect supplies and prevent waste.

Male reproductive health sometimes intersects with metabolic care. For background on a related topic being studied, read Dapagliflozin Male Infertility. For thyroid considerations during pregnancy planning, see Synthroid And Pregnancy.

Questions to Ask Your Clinician

• How will monitoring guide my timing and dose?
• Should I give it subcutaneously or intramuscularly?
• What signs of ovarian hyperstimulation should I report?
• How will we track testosterone or semen changes?
• Which supplies and needle sizes should I use?
• What is the plan if a dose is delayed?
• How should I store the mixed solution if not used right away?

Authoritative Sources

• FDA DailyMed
• Organon Manufacturer
• Health Canada DPD

Ready to proceed? Order from Borderfreehealth for convenient US shipping from Canada with prompt, express shipping and temperature-controlled handling when required. This information is not a substitute for medical advice; always follow your prescriber and the official label.