Salofalk® Suspension for Ulcerative Colitis

Salofalk® Suspension is a mesalamine rectal enema medicine for ulcerative colitis affecting the rectum and left colon. It targets inflammation at the site to help reduce bleeding, urgency, and stool frequency. This page explains how to use it, safety basics, and how you can arrange US shipping from Canada, even if you pay without insurance.

What Salofalk Is and How It Works

Salofalk® contains mesalamine, also called 5-aminosalicylic acid (5-ASA), in an enema form. The liquid spreads across the rectum and distal colon. It releases the anti-inflammatory drug directly on the bowel lining. The goal is to calm mucosal inflammation and support healing.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

As an anti-inflammatory aminosalicylate, it reduces local prostaglandin and leukotriene activity in the gut. The result can be less rectal bleeding and urgency. Many prescribers use it for active mild to moderate distal disease and for maintaining remission in that region. A common labeled presentation is mesalamine rectal suspension 4g/60mL.

Who It’s For

This treatment is used for adults with ulcerative proctitis or left-sided ulcerative colitis. It may also be used to help maintain remission in the distal colon after symptoms improve. People with known salicylate or aminosalicylate hypersensitivity should avoid this medicine. Those with severe kidney or liver problems may need alternative options or close monitoring by a clinician.

Discuss your history of kidney disease, liver disease, pancreatitis, or pyloric stenosis with a healthcare professional. Tell your prescriber about all allergies, including reactions to aspirin or sulfonamides. For broader context on the condition, see Ulcerative Colitis.

Some patients prefer rectal therapy to limit systemic exposure. Others combine rectal therapy with oral 5-ASA. If you are uncertain which route fits your plan, your prescriber can help you decide based on disease extent and recent colonoscopy findings. When topical coverage is needed high in the left colon, an enema often reaches further than a suppository.

Dosage and Usage

Follow your prescriber’s directions and the official label. Many adults use one enema at bedtime, often nightly during active flares. For maintenance, a reduced schedule can be used under clinical supervision. Shake the bottle well. Attach the applicator. Lie on your left side with left leg straight and right knee bent. Gently insert the applicator tip and instill the medicine slowly.

Remain lying for several minutes to help the liquid coat the left colon. Try to retain the enema for as long as possible, ideally until morning if used at bedtime. If rectal irritation occurs, tell your prescriber. Do not change the dose or schedule without medical advice. If you use both oral and rectal therapies, take them as directed to avoid gaps in coverage.

Strengths and Forms

This product is supplied as a rectal suspension enema. A commonly available kit includes a bottle and applicator. Availability can vary by country and by pharmacy partners. The typical labeled strength is 4 g per 60 mL per enema, intended for rectal use only. Do not ingest.

Kits and packaging may differ by manufacturer and market. If you prefer a smaller-volume rectal option, suppositories are another mesalamine form. Explore related options within our Gastrointestinal category. Some patients use suppositories for proctitis and enemas for higher left-sided disease. For catalog confirmation, check the product page before you order.

Product naming can differ across regions. The label may describe an administration set or box count. If you need a specific kit style, submit that information with your prescription. Salofalk rectal suspension kit 4g is one common reference.

Missed Dose and Timing

If you miss a dose, use it when you remember unless it is close to the next scheduled dose. If it is near the next time, skip the missed dose and resume your regular schedule. Do not double the dose to catch up. Consistency supports symptom control and mucosal healing. Bedtime use can help retention. Some patients also find weekend reminders or calendar alerts helpful.

Storage and Travel Basics

Store the enemas at room temperature as directed on the package. Keep the bottles in the original carton to protect from light and accidental puncture. Do not freeze. Keep out of reach of children and pets. When traveling, carry the kit in a protective pouch inside your hand luggage if permitted. Bring a copy of your prescription. Allow extra time for security checks and pack a spare applicator if your kit provides one.

Avoid prolonged exposure to excessive heat. Do not use if the solution is discolored or the bottle is damaged. If you have questions about storage requirements for your specific brand, review the package insert or speak with a pharmacist. For origin details of certain items, see Canada.

Benefits

Rectal 5-ASA therapy places medicine where inflammation is most active in distal disease. It can help reduce rectal bleeding, urgency, and nighttime trips to the bathroom. A liquid enema often reaches farther than a suppository, covering more of the left colon. This targeted route may limit systemic exposure compared with some oral options. Many patients use this therapy alone or as an add-on during flares for added local control.

Side Effects and Safety

• Common: rectal discomfort, abdominal cramping, gas, mild nausea
• Less common: headache, dizziness, increased bowel movements
• Local effects: anal irritation, urge to evacuate after instillation

Serious effects are uncommon but can include kidney problems, pancreatitis, hypersensitivity reactions, or worsening colitis-like symptoms. Seek urgent care for severe abdominal pain, blood in stool beyond baseline, fever, chest pain, rash with swelling, or breathing difficulty. Patients with kidney disease may need monitoring. Tell your clinician about previous reactions to aspirin or other salicylates. If you also use oral 5-ASA, or other anti-inflammatory therapies, report any unexpected symptoms promptly.

Drug Interactions and Cautions

Share a full medication list with your prescriber, including over-the-counter items and supplements. Use caution when combining with nephrotoxic drugs, certain immunomodulators, or other salicylates. Tell your clinician if you take azathioprine or 6-mercaptopurine. Report any new fatigue, abdominal pain, or yellowing of the skin. If you are pregnant, planning pregnancy, or breastfeeding, discuss risks and benefits.

Rectal products can stain fabrics. Protect bedding and clothing. If you have hemorrhoids or fissures, insertion may be uncomfortable; discuss a lubricant or technique adjustments. For related GI topics, you can read Dicyclomine Hcl For Ibs.

What to Expect Over Time

Some patients report decreased rectal bleeding and urgency after consistent nightly use. Others notice steady improvement over weeks as mucosal healing progresses. Your prescriber may adjust your overall plan if symptoms persist or extend beyond the reach of rectal therapy. Staying on schedule and retaining the enema as long as possible supports results. If you miss days regularly, consider reminders or pairing the dose with a bedtime routine you already follow.

During remission, clinicians sometimes taper to an intermittent schedule. Your plan should reflect disease extent, endoscopic findings, and symptom tracking. Keep a simple diary of urgency, bleeding, and stool frequency. Bring those notes to visits to help guide decisions. For broader cost guidance, you can review How Much Do Prescription Drugs.

Compare With Alternatives

Rectal mesalamine enemas are one option among several topical therapies for distal colitis. Budesonide foam offers a steroid alternative when aminosalicylate coverage is not enough or not tolerated. Another aminosalicylate enema brand may be used if your clinician prefers a specific formulation. Two options we carry include Pentasa Enema and Uceris Rectal Foam. Your prescriber can help select the right product based on disease reach, response, and tolerance.

Pricing and Access

We list transparent options to help you compare mesalamine rectal suspension price against your local pharmacy. Because we source through Canada, many patients see favorable cash-pay totals versus some U.S. outlets. You can browse current availability and add to your cart when your prescription is ready. We support encrypted checkout to protect your information. We provide US delivery from Canada with prescription verification.

If you are looking for savings, check occasional offers on our Promotions page. Benefits vary by product and timing. For education on overall medication spending, see our article linked above. Always compare options and confirm your prescriber’s plan before switching products.

Availability and Substitutions

Stock can vary by partner pharmacy and market supply. If a specific kit is unavailable, your prescriber may recommend an alternative in the same class or a different rectal therapy. If a substitution is suggested, your clinician should confirm it matches your treatment goals.

For cross-border ordering questions, many patients choose to order Salofalk from Canada through our platform once their prescription is on file. Our team coordinates with the dispensing pharmacy to confirm details. If we cannot fill a product, we will let you and your prescriber know so you can consider alternatives without delay.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with distal ulcerative colitis who can use rectal treatments and retain an enema. It may not suit those with severe allergy to salicylates, significant renal impairment, or severe hepatic disease. If you have difficulty retaining enemas, talk with your clinician about timing, bowel prep, or alternative formulations.

For budgeting, ask your prescriber about multi-month fills if appropriate. Larger fills can reduce per-shipment fees. Set calendar reminders for refills, especially before travel or holidays. If your plan involves both oral and rectal therapies, align refill dates to simplify adherence. Some patients compare mesalamine enema cash price at different times of year to plan their orders. Share any financial constraints with your clinician; simpler regimens can sometimes lower overall costs.

Questions to Ask Your Clinician

• Placement goals: how far should this enema reach for my disease
• Dosing plan: nightly duration, then maintenance steps
• Combination use: when to add oral 5-ASA or other agents
• Monitoring: labs or assessments for kidney or liver safety
• Technique: tips to improve comfort and retention
• Escalation: when to consider steroid foam or biologics

Authoritative Sources

Dr. Falk Pharma

DailyMed Mesalamine Rectal Products

Health Canada Drug Product Database

Ready to get started? Place your order with prompt, express shipping, and our team will coordinate prescription verification. This information is educational and not a substitute for medical advice.