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Xiidra® Ophthalmic Solution for Dry Eye Disease
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Xiidra is a prescription eye drop used to treat the signs and symptoms of dry eye disease. It targets inflammation on the eye surface to help reduce irritation and discomfort. You can compare options and place an order with US delivery from Canada, even if you pay without insurance.
What Xiidra Is and How It Works
Xiidra® contains lifitegrast, an LFA-1 antagonist that helps block inflammatory cell binding on the ocular surface. It is a targeted therapy for dry eye disease driven by inflammation. As an anti-inflammatory eye drop, it can help relieve burning, stinging, and fluctuating vision linked to dryness.
Lifitegrast ophthalmic solution 5% is supplied in sterile, single-use vials. Each vial is opened once and then discarded to reduce contamination risk.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
See the official label for full mechanism details and safety information. This page summarizes key points to help you discuss treatment with your prescriber.
Who It’s For
This treatment is indicated for adults with signs and symptoms of dry eye disease. It may be considered when artificial tears are not enough or when inflammation is suspected. People with a known allergy to lifitegrast or any component should not use it. Safety in pediatric patients has not been established.
Discuss pregnancy and breastfeeding considerations with a healthcare professional. Tell your prescriber about any other eye conditions or recent eye surgeries before starting therapy.
Dosage and Usage
The usual schedule is one drop in each eye twice daily, roughly 12 hours apart. Wash your hands, open a single vial, and avoid touching the tip to any surface. Use the vial immediately after opening and discard it after use. Many patients can treat both eyes from a single vial.
If you use other eye medicines, separate administration by at least five minutes. Contact lenses should be removed before dosing and may be reinserted after 15 minutes. Follow your prescriber’s instructions and the official label for complete directions. Xiidra 0.2 mL vials are designed for single use.
Strengths and Forms
Xiidra 5% single-use vials are packaged in foil pouches to protect the solution from light. Common carton sizes include multi-week supplies, which may be available as 30 or 60 single-use units depending on market availability.
Supply options can vary by pharmacy and region. Check available pack sizes on the product page before you place an order.
Missed Dose and Timing
If you miss a dose, use it as soon as you remember the same day. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not use two doses at once. Consistent twice-daily use supports best results over time. Consider keeping spare vials with your travel kit or work bag. Xiidra 30 vials may help you plan around trips and busy schedules.
Storage and Travel Basics
Store unopened vials in the original foil pouch, and keep the carton closed to protect from light. Keep at room temperature within the range indicated on the label, and do not freeze. After opening a vial, use the contents right away and discard the vial. Keep all medicines out of reach of children.
When traveling, carry vials in your hand luggage. Keep the pouches sealed until ready to use, and avoid leaving them in a hot car. Consider a small protective case to prevent crushing. Some orders use temperature-controlled handling when required, but these vials are generally stored at room temperature per labeling.
Pen Handling and Sharps Disposal
Not applicable. These are single-use vials, not pens or injectors. Discard each empty vial and tip in household trash unless local regulations advise otherwise.
Benefits
This medicine targets ocular surface inflammation, which can drive dry eye symptoms. Many patients find it easier to stick to a twice-daily schedule compared with more frequent artificial tears. Single-use vials lower the contamination risk that can come with multi-dose bottles.
The treatment can be used alongside other dry eye therapies when advised by a clinician. Spacing different drops allows each product to work as intended.
Side Effects and Safety
- Eye irritation or discomfort after instillation
- Temporary blurred vision
- Eye redness or watering
- A bitter or unusual taste after dosing
- Headache
Serious reactions are uncommon but can include hypersensitivity, significant eye pain, or vision changes. Stop use and seek medical help if you notice swelling, rash, or severe irritation. Hypoglycemia risk does not apply to this class, but coordination with other prescriptions is still important. Always report persistent symptoms to a healthcare professional.
Drug Interactions and Cautions
Space this drop from other ophthalmic medicines by at least five minutes to reduce washout. Remove contact lenses before use and wait 15 minutes before reinserting them. Tell your prescriber about all topical and systemic medicines you use, including over-the-counter products and supplements.
Do not use the vial tip if it has touched your eye, fingers, or any surface. Contamination can cause serious eye infections.
What to Expect Over Time
Symptoms may ease gradually with regular use. Some people first notice less burning or grittiness, then more comfortable screen time or reading. Others may feel a brief stinging on instillation that lessens with routine. Keep dosing as directed unless your prescriber advises changes.
Use preservative-free artificial tears as instructed to support comfort between doses. Adherence is important because inflammatory pathways can take time to quiet.
Compare With Alternatives
For chronic dry eye driven by inflammation, cyclosporine drops are another option your prescriber may consider. We offer Cequa and Cyclosporine. Your clinician can help decide which class is suitable based on your history, tolerability, and goals.
Pricing and Access
Many patients compare Canadian options to reduce out-of-pocket costs. You can review Xiidra price without insurance on the product page and see current supply options. Listings reflect Canadian dispensing, with US shipping from Canada. Checkout is encrypted to protect your information.
If you are looking for Xiidra Canadian pricing, use the pricing tab to compare available pack sizes. Pharmacists will dispense once a valid prescription is on file. See current offers on our Promotions page when available.
Availability and Substitutions
Supply can vary by pharmacy. If your item is temporarily unavailable, a prescriber may recommend an alternative in the same therapeutic class or a different approach based on your history. Buy lifitegrast eye drops only with guidance from your clinician and the product label for safe use.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults with inflammatory dry eye symptoms who can follow a twice-daily routine. It may not suit patients with known lifitegrast allergy or those unable to avoid contact lens wear during dosing. Share your full medical and ocular history with your prescriber.
To save on total costs, consider a multi-month supply if approved. Set refill reminders so you do not run out during travel or busy periods. Store extra cartons properly and check the pouch expiration date before you use a vial.
Questions to Ask Your Clinician
- Is this class appropriate for my type of dry eye?
- How should I space this drop from other eye medicines?
- What should I do if stinging persists after dosing?
- Can I keep using artificial tears and warm compresses?
- When should I schedule follow-up to assess response?
- Are cyclosporine options reasonable if I cannot tolerate this?
Authoritative Sources
Manufacturer | DailyMed | Health Canada DPD
Learn more about dry eye care in our resources: Dry Eye, Ophthalmology, and Canada. You can also explore articles like Xiidra Eye Drops Relief, Restasis Vs Xiidra, Azopt Eye Drops, Alphagan Eye Drops, and Lotemax Vs Alrex.
Order from Border Free Health with prompt, express shipping. Ships from Canada to US. This content is informational and is not a substitute for professional medical advice. Always follow your prescriber’s instructions and the official label.
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How do these drops work for dry eye?
The active ingredient blocks LFA-1 from binding to ICAM-1 on the ocular surface. That action helps reduce T-cell–mediated inflammation, a key driver of dry eye symptoms such as burning, stinging, and irritation. The drops are used twice daily in both eyes. Many people also use preservative-free artificial tears between doses if advised. Follow the official label and your prescriber’s guidance for the safest use.
Can I use it with contact lenses?
Remove contact lenses before dosing. Wait at least 15 minutes after instilling the drop before reinserting lenses. This timing helps avoid lens absorption of the solution and reduces irritation. If you use multiple ophthalmic products, space them by at least five minutes so one does not wash out the other. Ask your clinician if lens wear should be limited during flare-ups.
What side effects should I watch for?
Common effects include temporary eye irritation or discomfort, blurred vision, redness, watering, and an unusual taste after dosing. These are typically mild and short-lived. Stop use and seek care if you notice severe eye pain, swelling, rash, or vision changes. To reduce contamination risk, avoid touching the vial tip to your eye, skin, or any surface, and discard each vial immediately after use.
How should I store the vials?
Keep unopened vials in the foil pouch inside the carton to protect from light. Store at room temperature within the label’s recommended range and do not freeze. Open a vial only when ready to dose, then discard it after use. When traveling, carry vials in your hand luggage and avoid leaving them in hot cars. Keep all medicines out of reach of children.
What if I miss a dose?
Use the missed dose as soon as you remember on the same day. If it is close to your next scheduled time, skip the missed dose and resume your usual routine. Do not double up to make up for a missed dose. If you miss doses often, set phone reminders or tie dosing to daily routines like breakfast and bedtime. Ask your prescriber for additional guidance if needed.
Can I use other eye drops with it?
Yes, many patients use artificial tears or other ophthalmic prescriptions during treatment. Separate different drops by at least five minutes to reduce washout. If you also use an ointment, typically apply it last. Your prescriber can help you set an order of use that fits your regimen and reduces irritation.
Who should avoid starting this medicine?
People with a known allergy to lifitegrast or any component should not use it. Safety in children has not been established. Discuss pregnancy, breastfeeding, and recent eye surgery with a healthcare professional before starting. Share all medicines and supplements you use. Your clinician will consider your eye history and overall health when deciding if this therapy is suitable.
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