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Eliquis Side Effects

How to Identify and Handle Eliquis Side Effects

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Summary: Eliquis side effects include common issues like bruising, nausea, and fatigue, as well as serious risks such as severe bleeding and allergic reactions. Prompt management, lifestyle adjustments, and regular communication with healthcare providers are essential to ensure safe and effective treatment while minimizing complications.

Eliquis (apixaban) is a prescription anticoagulant or blood thinner widely used to prevent blood clots and reduce the likelihood of stroke in individuals with atrial fibrillation, deep vein thrombosis (DVT), and pulmonary embolism. While it offers significant benefits in managing clotting disorders, Eliquis also carries potential side effects, some of which can be serious. Being able to identify these side effects early and knowing how to respond is essential for ensuring patient safety and improving treatment outcomes.

This article will help you understand the common, uncommon, and serious Eliquis side effects, how to handle them, and when to seek medical assistance.

Common Side Effects of Eliquis

While not everyone will experience side effects, it is crucial to be aware of the most common ones. These side reactions often diminish over time as the body adjusts to the medication, but they can still cause discomfort.

Bleeding or Bruising Easily

Since Eliquis thins the blood, it can increase the likelihood of bleeding. Patients may experience:

  • Easy bruising without trauma
  • Minor cuts that take longer to stop bleeding
  • Frequent nosebleeds
  • Bleeding gums, especially during brushing or flossing
What to do:
  • Use a soft toothbrush to minimize gum irritation.
  • Apply pressure on cuts for a longer time to help stop bleeding.
  • Avoid activities with a high likelihood of injury.
  • If bleeding becomes persistent or severe, consult a healthcare provider.

Nausea and Upset Stomach

Nausea, stomach pain, or indigestion may occur, particularly when first starting Eliquis.

What to do:
  • Take the medication with food or water to reduce stomach discomfort.
  • If symptoms persist, talk to your doctor about using antacids or switching to a different schedule for taking the medication.

Fatigue or Weakness

Some individuals on Eliquis report feeling unusually tired or weak. This could be due to mild bleeding or the body adjusting to the medication.

What to do:
  • Get plenty of rest and stay hydrated.
  • Monitor your energy levels; if weakness persists or worsens, consult your healthcare provider.

Uncommon Eliquis Side Effects

These side effects are less frequent but may still occur in some individuals. Monitoring and reporting these symptoms promptly can help prevent complications.

Dizziness or Lightheadedness

Eliquis can occasionally cause low blood pressure, leading to dizziness or a lightheaded sensation, especially when standing up too quickly.

What to do:
  • Stand up slowly to prevent sudden dizziness.
  • Increase fluid intake to maintain blood pressure.
  • If dizziness is frequent or severe, consult your healthcare provider.

Mild Skin Rash or Itching

Some people may develop a mild allergic reaction to Eliquis, resulting in a rash or itching.

What to do:
  • Use over-the-counter antihistamines to manage mild itching.
  • Moisturize the skin to reduce dryness and irritation.
  • If the rash spreads or worsens, notify and call your doctor.

Serious Eliquis Side Effects Requiring Immediate Medical Attention

In rare cases, Eliquis can cause severe side effects that demand urgent care. If you or a loved one experiences any of the following symptoms, contact a healthcare provider immediately or go to the nearest emergency room.

Severe Bleeding

Excessive blood thinning can lead to life-threatening bleeding. Signs to watch for include:

  • Blood in urine or stool (black, tarry stools)
  • Coughing or vomiting blood
  • Heavy menstrual bleeding
  • Unexplained swelling or pain in the joints (due to internal bleeding)
What to do:
  • Stop taking Eliquis and seek emergency care if severe bleeding occurs.
  • A medical professional may administer a reversal agent, such as andexanet alfa, to stop the bleeding.

Allergic Reaction (Anaphylaxis)

Though rare, some individuals may have a severe allergic reaction to Eliquis. Symptoms include:

  • Difficulty breathing or wheezing
  • Swelling and inflammation of the face, lips, tongue, or throat
  • Hives or severe itching
What to do:
  • Use an epinephrine auto-injector (if available) and call for an emergency medical help immediately.
  • Discontinue the medication only under the guidance of your doctor.

Liver Problems

Eliquis may affect liver function in rare cases. Symptoms of liver issues include:

  • Yellowing of the skin or eyes (jaundice)
  • Dark urine and pale stools
  • Persistent fatigue or abdominal pain
What to do:
  • Inform your healthcare provider if you encounter these symptoms. Liver function tests may be required to assess any damage.

Managing Side Effects: Practical Tips

Handling side effects effectively involves open communication with your healthcare provider and some lifestyle adjustments.

Monitor Your Symptoms Regularly

Keep a symptom diary to track any side effects. This information can be valuable when discussing concerns with your doctor. Pay attention to any new or unusual symptoms, as these could indicate a more serious issue.

Consult Your Doctor Before Stopping Medication

Never stop taking Eliquis without consulting your healthcare provider. Suddenly discontinuing the medication increases the risk of blood clots and stroke.

Adjusting Dosage or Medication

In some cases, your doctor may adjust your dose or switch you to another anticoagulant if the side effects are severe. Always follow medical advice regarding any changes.

Lifestyle Modifications to Minimize Risks

Avoid alcohol, which can elevate the risk of bleeding. Be cautious with over-the-counter medications like aspirin, NSAIDs (ibuprofen or naproxen), and herbal supplements that can also thin the blood. Use protective equipment during physical activities to reduce the risk of injury.

When to Seek Medical Attention

If you experience any of the following symptoms, seek medical attention promptly:

  • Severe or uncontrollable bleeding
  • Signs of an allergic reaction
  • Symptoms of a stroke, including sudden numbness, confusion, or difficulty speaking
  • Chest pain or trouble breathing, which could indicate a pulmonary embolism

Conclusion

Eliquis is a powerful medication that can significantly lessen the likelihood of dangerous blood clots and strokes. However, like all medications, it comes with potential side effects that can vary in severity. Identifying these Eliquis side effects early and knowing how to handle them is crucial for maintaining your health.

Most common side effects, like bruising or mild nausea, are manageable with minor adjustments, but more serious issues, such as severe bleeding or allergic reactions, require immediate medical attention. Whether using the brand medication or an Eliquis generic, regular communication with your healthcare provider and taking steps to minimize risks will help you stay safe and get the most benefit from your treatment.

Remember, never ignore new or worsening symptoms, and always follow your doctor’s guidance when it comes to medication adjustments or discontinuation. By staying informed and proactive, you can effectively manage Eliquis side effects and continue to protect yourself from clotting-related health issues. 

Frequently Asked Questions (FAQs)

How long does it take for Eliquis side effects to go away?


Some side effects, such as nausea or fatigue, may improve within a few days to weeks as your body adjusts to the medication. However, side effects like easy bruising may persist throughout treatment due to the blood-thinning effects. If side reactions are severe or persistent, contact your healthcare provider.

Can I take painkillers while on Eliquis?


It is generally advised to avoid nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin, as these can increase the risk of bleeding. If you need pain relief, talk to your doctor about safer alternatives, such as acetaminophen (Tylenol).

What should I do if I miss a dose of Eliquis?


If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule.  

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Written by BFH Staff Writer on October 25, 2024

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