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Triazide

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Uses of Triazide

Triazide contains a combination of 2 drugs, triamterene and hydrochlorothiazide: Triamterene helps the body lose excess salt but keep a normal amount of potassium (an electrolyte) in the blood. Hydrochlorothiazide is a diuretic or “water pill” that increases urination. This lowers blood pressure.

Precautions and Warnings

Before you use Triazide talk to your doctor, nurse, or pharmacist if you:

  • Are allergic to penicillin.
  • Have diabetes, liver or kidney disease.
  • Have a history of kidney stones.
  • Have lupus or gout.
  • Are dehydrated or suffer from excessive vomiting, diarrhea, or sweating.
  • Are using any form of potassium supplementation.
  • Are taking any other potassium-conserving medications or “water pills”.
  • Are pregnant or thinking of becoming pregnant.
  • Are less than 18 or over 65 years old of age.
  • Have had skin cancer or have a family history of skin cancer.
  • Have a greater chance of developing skin cancer because you have light-coloured skin, get sunburned easily, or are taking drugs to suppress your immune system.

Risk of skin cancer:

Triazide contains hydrochlorothiazide. Treatment with hydrochlorothiazide may increase the risk of developing non-melanoma skin cancer. The risk is higher if you have been taking Triazide for many years (more than 3) or at a high dose.

While taking Triazide :

  • Make sure to regularly check your skin for any new lesions. Check areas that are most exposed to the sun, such as the face, ears, hands, shoulders, upper chest and back.
  • Limit your exposure to the sun and to indoor tanning. Always use sunscreen (SPF-30 or higher) and wear protective clothing when going outside.
  • Talk to your doctor immediately if you get more sensitive to the sun or UV light or if you develop an unexpected skin lesion (such as a lump, bump, sore, or patch) during the treatment.

Hydrochlorothiazide in Triazide can cause Sudden Eye Disorders:

  • Myopia: sudden nearsightedness or blurred vision.
  • Glaucoma: an increased pressure in your eyes, eye pain. Untreated, it may lead to permanent vision loss.

These eye disorders are related and can develop within hours to weeks of starting Triazide .

You may become sensitive to the sun while taking Triazide . Exposure to sunlight should be minimized until you know how you respond.

Driving and using machines: Before you perform tasks which may require special attention, wait until you know how you respond to Triazide Dizziness, lightheadedness, or fainting can especially occur after the first dose and when the dose is increased.

Dosage

Patients should be individually titrated for each component separately.

For Edema: usually 1 tablet twice daily. In some patients, one tablet every day or every other day may be indicated.

For Hypertension: usually 1 tablet twice daily, dosage may be increased or decreased according to patient’s need. Maximum daily dose should not exceed 4 tablets.

Do not adjust your dosage by yourself. Please consult your doctor and follow the given advice.

Side Effects

Common Side Effects:

  • muscle cramps, spasms, and pain, weakness, restlessness
  • dizziness, pins and needles in your fingers, headache
  • constipation, diarrhea, nausea, vomiting, decreased appetite, upset stomach, enlargement of the glands in your mouth, dry mouth
  • reduced libido
  • bleeding under the skin, rash, red patches on the skin

 

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