Please note: a valid prescription is required for all prescription medication.
Actonel® Tablets for Osteoporosis
Buy more, save more: Get 20% off when you buy 3 or more of any one product. Use code LESS20 at checkout.
Coupon code cannot be combined with other offers. Sale applies to all products originating from Canada. Maximum allowable quantity equal to a 90 day supply per single order.
Price range: $94.00 through $97.53
Secure Encrypted Payments
Actonel® is a prescription bisphosphonate tablet for osteoporosis and Paget disease. This page explains safe use, compares options, and supports your order with US shipping from Canada. You can review typical out-of-pocket costs without insurance before you decide.
What Actonel Is and How It Works
This medicine contains risedronate, a bisphosphonate that helps slow bone loss. It attaches to bone mineral and reduces osteoclast activity, which can help improve bone strength over time. The treatment is used in postmenopausal osteoporosis, osteoporosis in men, glucocorticoid-induced bone loss, and Paget disease of bone. Learn more about the condition in our Osteoporosis guide.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
You take it first thing in the morning with plain water and remain upright to lower esophageal irritation. It should be combined with adequate calcium and vitamin D intake unless contraindicated. See class basics in Bisphosphonate Drugs.
Who It’s For
This therapy is for adults with osteoporosis who need to reduce fracture risk. It also treats active Paget disease in appropriate patients. People with esophageal abnormalities, an inability to stay upright for at least 30 minutes, low blood calcium, or severe kidney issues should avoid it unless a prescriber advises otherwise. See more about Paget Disease and Glucocorticoid Induced Osteoporosis.
For some patients, Actonel once a week fits lifestyle needs, while others use a monthly schedule. Your healthcare professional will choose a plan that aligns with your history and risk profile.
Dosage and Usage
Take the tablet first thing in the morning, before food or other drinks. Swallow with a full glass of plain water only. Do not lie down for at least 30 minutes after swallowing. Avoid food, beverages, and other medicines during that 30-minute window, unless your prescriber gives specific instructions.
Weekly schedules are common for osteoporosis. Some patients use a monthly regimen. Paget disease may involve a daily course for a limited time based on the official label. For a monthly option, many patients are prescribed Actonel 150 mg once a month. Always follow the exact directions from your prescriber and the package insert.
Review related class information here: What Is Alendronate Used For and Fosamax Generic.
Strengths and Forms
This treatment is supplied as oral tablets in strengths that support daily, weekly, and monthly plans. Availability can vary by manufacturer and market. Common packaging supports either once-weekly or once-monthly dosing based on your clinician’s guidance.
Patients often ask about Risedronate 35 mg tablets for weekly use, as well as a monthly tablet option. Your prescriber will match the strength to your diagnosis and bone health goals.
Missed Dose and Timing
If you miss a weekly dose, take one tablet the morning you remember, then return to your original day the following week. Do not take two on the same day. For monthly schedules, take the missed tablet the morning you remember if your next planned date is more than a week away; otherwise, wait until the next planned date. If you are unsure, consult the official label or ask a healthcare professional.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from moisture and out of reach of children. Keep the medicine in its original container until use. When traveling, carry it in your hand luggage with a copy of your prescription. Keep tablets out of direct heat and humidity. If your trip involves time zone changes, set reminders so dosing remains on the intended day. Some orders include handling best practices; we use temperature-controlled handling when required.
For broader therapy planning, review Osteoporosis Treatment Options and our Womens Health category.
Benefits
Bisphosphonate therapy can help increase bone mineral density and reduce fracture risk when used as directed. Weekly or monthly dosing supports adherence. Morning dosing and clear steps help standardize your routine. Combining this medicine with adequate calcium and vitamin D intake, weight-bearing exercise, and fall-prevention strategies may support bone health as part of a comprehensive plan.
Side Effects and Safety
- Stomach upset or heartburn
- Abdominal pain or nausea
- Muscle, bone, or joint pain
- Headache
- Diarrhea or constipation
Serious risks are uncommon but can include esophagitis, ulcers of the esophagus, severe bone, joint, or muscle pain, low calcium levels, and rare events such as osteonecrosis of the jaw or unusual thigh fractures. Dental procedures may increase certain risks; tell your dentist you take a bisphosphonate. If you develop chest pain, new or worsening heartburn, or painful swallowing, stop taking the tablet and contact a clinician.
Drug Interactions and Cautions
Calcium, iron, magnesium, antacids, and multivitamins can reduce absorption if taken too close to the tablet. Separate them by at least 30 minutes after dosing, or longer if advised. Nonsteroidal anti-inflammatory drugs can irritate the stomach and may increase gastrointestinal effects. Use caution with other osteoporosis agents unless directed by your prescriber. Do not use if you cannot sit or stand upright for 30 minutes, have low blood calcium, or have certain esophageal disorders. Kidney impairment may require different choices.
What to Expect Over Time
Many people will not feel immediate effects because bone remodeling changes slowly. Your clinician may monitor bone mineral density and assess fracture risk over time. Good adherence to the dosing steps supports effectiveness and reduces esophageal irritation. If your situation or other medicines change, your prescriber may revisit the plan. Lifestyle measures, such as exercise and fall prevention, remain important alongside therapy.
Compare With Alternatives
Some patients do well on a generic bisphosphonate with a similar weekly schedule, such as Alendronate. Others may be candidates for an injectable option given less often, such as Prolia Prefilled Syringe. Your clinician will consider fracture risk, convenience, and medical history when selecting a therapy.
Pricing and Access
Our pharmacy partners offer Canadian pricing with transparent checkout. If you are comparing options, search for Risedronate sodium price to understand how generic supply can affect your total expense. We provide clear steps to upload your prescription and complete payment. Orders are packaged for safety and ship discreetly. Ships from Canada to US is supported for eligible prescriptions.
Looking for a deal? See current site offers on our Promotions page. For questions about coverage or paperwork, our team can help you review next steps.
Availability and Substitutions
Supply can vary by manufacturer and strength. If your requested brand is not available, your prescriber may recommend the approved generic. Many patients use Actonel generic when appropriate. Your pharmacy will dispense exactly what your prescriber authorizes, and may contact them if a substitution is needed.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults with osteoporosis who can follow the morning empty-stomach routine and remain upright for 30 minutes. It may not suit patients with esophageal disorders, severe kidney impairment, or very low calcium. People who need fewer gastrointestinal effects might consider other classes after discussing options.
To manage costs, ask your prescriber about multi-month fills when appropriate, and set refill reminders so you do not miss doses. If paying cash, compare the Risedronate cash price across strengths and pharmacies. Keep packaging and directions handy, especially when traveling, so you can follow the steps consistently.
Questions to Ask Your Clinician
- Right candidate: Is a bisphosphonate the best first choice for my risk?
- Dosing plan: Should I use a weekly schedule or a monthly option?
- Administration: How can I reduce esophageal irritation with this tablet?
- Supplements: How should I time calcium or vitamins around my dose?
- Dental health: Do I need a dental exam before starting this therapy?
- Monitoring: When will we reassess bone density and fracture risk?
- Duration: If I respond well, how long might I stay on treatment?
Authoritative Sources
DailyMed: Risedronate SodiumHealth Canada Drug Product Database
Ready to proceed? You can place your request at BorderFreeHealth with prompt, express shipping and US delivery from Canada. This page is informational and does not replace advice from your healthcare professional.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
How long does it take for Actonel to work?
Bone density improvements can be seen within 6 months to a year, but fracture risk reduction may take longer.
Can I take Actonel at night?
No, Actonel must be taken in the morning on an empty stomach to ensure proper absorption and minimize side effects.
Do I need to take calcium and vitamin D with Actonel?
Yes, adequate calcium and vitamin D intake is important for bone health. Your doctor may recommend supplements if needed.
Can Actonel be stopped once my bones improve?
Your doctor will determine the duration of treatment. Some patients may need periodic breaks from bisphosphonates to reduce long-term risks.
Is Actonel safe for long-term use?
Actonel is effective for long-term bone health, but extended use may increase certain risks. Your doctor will assess your need for continued treatment.
How does risedronate work to help bones?
Risedronate belongs to a class called bisphosphonates. It binds to bone mineral and reduces activity of osteoclasts, the cells that break down bone. Over time, this can help increase bone mineral density and lower fracture risk when combined with adequate calcium, vitamin D, and lifestyle measures. Because bone remodeling is gradual, your clinician may monitor progress periodically rather than expecting quick changes.
What is the difference between weekly and monthly dosing?
Both schedules aim to deliver the same class effect using different intervals. Weekly dosing may be better for people who prefer consistent routines. Monthly dosing suits those who like fewer dosing days. Each approach requires taking the tablet on an empty stomach with plain water and staying upright for at least 30 minutes. Your healthcare professional will match the plan to your history and preferences.
Can I take this medicine with calcium or antacids?
Take the tablet first thing in the morning with plain water only. Wait at least 30 minutes before consuming food, drinks, calcium, iron, magnesium, antacids, or multivitamins, unless your prescriber gives other instructions. These products can bind the medicine and reduce absorption if taken too close together. If you are unsure about timing, follow the official label or ask a clinician for guidance.
What are serious risks I should know about?
Serious risks are uncommon, but can include esophagitis or ulcers of the esophagus, low blood calcium, severe bone or joint pain, osteonecrosis of the jaw, and rare atypical thigh fractures. Tell your dentist you take a bisphosphonate before dental procedures. If you develop chest pain, new or worsening heartburn, or painful swallowing, stop the tablet and seek medical advice promptly.
How long will I need to stay on therapy?
Duration varies based on fracture risk, bone density, and response. Many patients use a bisphosphonate for a defined period, then their clinician reassesses whether to continue, pause, or switch. The decision should include your risk profile, preferences, and any side effects. Do not stop or restart without discussing it with your prescriber, as consistency is important for benefit.
What if I miss a dose on my schedule?
If you miss a weekly dose, take one the morning you remember, then return to your usual day the following week. Do not take two on the same day. For monthly dosing, take it the morning you remember if your next planned date is more than a week away; otherwise, skip and take it on your next planned date. When uncertain, follow the label or ask a healthcare professional.
Is generic risedronate as effective as the brand?
Approved generics must meet bioequivalence standards set by regulators. That means the active ingredient and expected effect are comparable within accepted ranges. Many patients use a generic after discussing options with a prescriber. If you notice unexpected changes after a switch, let your clinician know so they can review your plan and address any concerns.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
How to book an appointment
- 1Create Begin by completing a profile or log into your existing account. This step ensures we have the necessary information to provide you with a service that's tailored to your needs. account and start earning.
- 2Scheduling an appointment with our online booking system is easy. Pick a day and time that suits you. You’ll receive an immediate confirmation, without the wait.
- 3Discuss your concerns and symptoms and receive a thorough diagnosis from one of our licensed doctors during a confidential video appointment.
- 4If you've been prescribed medication, your Rx is sent directly to one of our licensed pharmacies and delivered right to your door.
Get Started
To book an online doctor appointment, register for an account or login. After doing so, you can book your visit on this page.


