Celsentri® Tablets for HIV-1

This prescription helps manage CCR5‑tropic HIV‑1 as part of a combination regimen. This page explains how it works, safety basics, and how to request access with US shipping from Canada, even without insurance.

What Celsentri Is and How It Works

Celsentri® is maraviroc, a CCR5 antagonist used with other antiretrovirals. It binds to the CCR5 receptor on certain immune cells, which may block CCR5‑tropic HIV‑1 from entering those cells. The treatment does not work for viruses that use CXCR4 or have dual/mixed tropism. Prescribers confirm viral tropism before starting therapy and throughout care when clinically indicated.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

By targeting a human co‑receptor rather than viral enzymes, this medicine offers an option when resistance or tolerability issues limit other classes. It is taken orally and is combined with a fully active background regimen to support durable suppression. Explore related class options in Antivirals.

For clarity, Celsentri tablets are approved for treatment, not for pre‑exposure prevention. The treatment can be taken with or without food, which supports flexible daily routines.

Who It’s For

This medicine is indicated for adults and certain pediatric patients who have CCR5‑tropic HIV‑1, in combination with other antiretrovirals. A standardized tropism assay guides selection. It is not recommended if testing shows CXCR4 or dual/mixed tropism. People with prior treatment experience may be considered when a fully active regimen can be built.

Maraviroc tablets may be avoided in patients with severe hepatic impairment unless a prescriber determines benefits outweigh risks. Caution is advised in those with cardiovascular disease, postural hypotension risk, or renal impairment using interacting medicines. For condition education and options, see HIV.

Dosage and Usage

Standard administration is twice daily with or without food, alongside a fully active background regimen. The exact dose is determined by the prescriber based on co‑medications and clinical factors.

Celsentri 150 mg appears in some regimens when used with potent CYP3A inhibitors, per the product label. Always follow the directions on your prescription label and consult the official information if questions arise. Swallow tablets whole with water.

Consistency helps treatment success. Taking doses at the same times each day and aligning them with daily routines can support adherence. If the care team changes co‑medications, they will reassess the appropriate dose using the approved labeling.

Strengths and Forms

This treatment is supplied as film‑coated oral tablets in commonly published strengths. Availability may vary by pharmacy and manufacturer supply.

• Celsentri 300 mg
• 150 mg tablet presentation may also be available

Package sizes and manufacturers can differ by market. Pharmacists may dispense equivalent packaging from licensed sources in accordance with the prescription.

Missed Dose and Timing

If a dose is missed, it may be taken when remembered unless it is close to the next scheduled dose. In that case, skip the missed dose and resume the regular schedule. Do not double doses. If vomiting occurs shortly after a dose, consult a healthcare professional for guidance. Consistent daily timing helps maintain steady exposure within a combination regimen.

Storage and Travel Basics

Store your tablets at room temperature in a tightly closed container. Keep them dry, away from excess heat, and out of reach of children and pets. Do not use tablets that are damaged or past the labeled expiration date.

When traveling, carry your medicine in original labeled packaging in your hand luggage. Bring a copy of your prescription and a medication list. If crossing borders, allow extra time for screening and keep documentation accessible. Use a travel pill organizer only if it is clean, dry, and clearly labeled. For longer trips, plan refills early to avoid interruptions.

Benefits

As a CCR5 antagonist, this therapy offers a distinct mechanism that may help when resistance or intolerance affects other classes. It can be taken without regard to meals, which supports schedule flexibility. The agent is designed for use with an optimized background regimen, aiming to reduce viral load and support immune recovery when the virus is confirmed to be CCR5‑tropic. Class diversification within a regimen can also provide options when drug‑drug interactions limit choices.

Side Effects and Safety

• Common: cough, upper respiratory symptoms
• Common: dizziness, headache, tiredness
• Common: nausea, diarrhea, abdominal discomfort
• Common: rash or itching
• Common: musculoskeletal or joint aches

Serious risks can include liver problems (sometimes preceded by rash or allergic symptoms), severe skin reactions, postural hypotension, and cardiovascular events. Immune reconstitution phenomena may occur after starting combination therapy. Seek urgent care for signs of severe rash, yellowing skin or eyes, dark urine, fainting, or chest pain. This medicine is used only within a combination regimen under clinical supervision.

Drug Interactions and Cautions

Maraviroc is metabolized by CYP3A. Strong CYP3A inhibitors or inducers can change drug levels and may require prescriber‑directed dose adjustments per the label. Avoid St John’s wort. Use caution with other medicines that lower blood pressure or that have overlapping hepatotoxicity risk. People with renal or hepatic impairment require careful assessment. For broader context on HIV regimens and prevention options, see HIV Medications Options.

What to Expect Over Time

When combined with an optimized background regimen and after confirming CCR5 tropism, therapy may support declines in viral load and improvements in immune markers. The clinical team will monitor viral response and safety labs and may repeat tropism testing if virologic failure occurs. Staying on schedule, coordinating pharmacy refills, and promptly reporting side effects can help maintain continuity of care.

Compare With Alternatives

Several approved options from other classes are commonly used in optimized regimens. Integrase‑based combinations are frequent first‑line choices when appropriate.

• Dovato: a two‑drug regimen that combines an integrase inhibitor with a nucleoside reverse transcriptase inhibitor.
• Delstrigo: a once‑daily triple combination built around doravirine.

Selection depends on prior treatment, resistance testing, interactions, co‑morbidities, and patient preferences. Discuss choices with a healthcare professional.

Pricing and Access

Celsentri cost varies by strength, supply, and dispensing pharmacy. Our platform lists current options so you can compare and request fulfillment with US delivery from Canada. Look for deals on branded and generic therapies when available.

Interested in savings opportunities? See our current offers on the Promotions page. Pricing can differ by manufacturer and packaging; check the product page for the latest availability and checkout details.

For background education on treatment approaches, you can also review this helpful overview: HIV Treatment Guide. For mechanism and therapy planning insights, see How It Works.

Availability and Substitutions

Supply can vary by market, manufacturer, and strength. Maraviroc from Canada may be available through licensed partner pharmacies based on your valid prescription. If a specific presentation is not in stock, a prescriber may recommend an appropriate alternative from another class or a different combination to fit the overall regimen.

Country‑of‑origin and packaging details can appear on each listing. For source transparency, explore Canada on the product page when shown.

Patient Suitability and Cost-Saving Tips

Candidates generally include patients with confirmed CCR5‑tropic HIV‑1 who can build a fully active background regimen. It may not suit those with CXCR4 or dual/mixed tropism, significant hepatic disease, or certain cardiovascular risks unless a prescriber advises otherwise. A formal tropism test is essential before starting and if virologic failure is suspected later.

To manage out‑of‑pocket exposure, compare options across strengths and pack sizes. Generic Maraviroc price may differ across manufacturers and dispensing pharmacies. Multi‑month fills can reduce per‑fill fees and help adherence. Set refill reminders and coordinate lab visits so treatment is not interrupted. Our encrypted checkout supports private, secure ordering.

Questions to Ask Your Clinician

• Tropism testing: which assay will confirm CCR5‑tropic virus for my regimen?
• Background regimen: which companion drugs are fully active based on my history?
• Interactions: do any current medicines or supplements affect maraviroc exposure?
• Monitoring: which labs and follow‑ups are needed during the first months?
• Safety: what signs of liver or skin reactions should prompt urgent evaluation?
• Cardiovascular risk: is postural hypotension a concern with my conditions?
• Pregnancy and lactation: how is use assessed in these situations?

Authoritative Sources

• ViiV Healthcare
• DailyMed: Maraviroc
• Health Canada DPD

Ready to proceed? Start your request with prompt, express shipping. Ships from Canada to US. Prescription required. This page is informational and does not replace medical advice; always follow your prescriber’s guidance and the official label.