Please note: a valid prescription is required for all prescription medication.
Cytomel® Tablets for Hypothyroidism
Buy More, Save More: Get 20% off when you buy 3 or more of any one product using code LESS20 at checkout.
Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
Price range: $197.99 through $461.99
Secure Encrypted Payments
Cytomel® is liothyronine sodium used to treat hypothyroidism and related thyroid disorders. This page outlines how it works, safe-use basics, and ways to access therapy. We support US delivery from Canada and explain options for Liothyronine without insurance.
What Cytomel Is and How It Works
Cytomel® contains liothyronine, a synthetic form of triiodothyronine (T3). T3 helps regulate metabolism, energy use, and body temperature. When the thyroid does not produce enough hormone, this medicine replaces or supplements what the body is missing.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Unlike levothyroxine (T4), liothyronine is the active hormone. It may be considered when T4 alone is not suitable based on a prescriber’s judgment. Cytomel tablets are taken by mouth and work systemically to restore thyroid balance.
Who It’s For
This treatment is indicated for primary, secondary, or tertiary hypothyroidism, including cases after surgery, radiation, or certain medications. It is also used for simple, non-toxic goiter and as part of diagnostic suppression testing under medical supervision. Liothyronine tablets are generally reserved for patients whose clinicians consider T3 appropriate.
People with uncorrected adrenal insufficiency should not use this therapy. Those with heart disease, arrhythmias, or angina need careful evaluation and monitoring. For pregnancy and lactation, prescribers typically continue thyroid replacement and adjust as needed per the official label.
Explore condition guides for context: Hypothyroidism and Myxedema Coma. For broader options, see our Endocrine Thyroid category.
Dosage and Usage
Follow your prescription label exactly. Take the medicine consistently, ideally at the same time every day. Swallow tablets with water. Many clinicians advise taking thyroid hormone on an empty stomach, separate from certain vitamins or binders, to help absorption.
The label provides typical titration guidance. Liothyronine 25 mcg may appear in some treatment schedules, but individual dosing depends on clinical factors and ongoing lab monitoring. Do not change your dose without professional direction.
Because some foods and supplements interfere with thyroid hormone, timing matters. See additional nutrition tips here: Foods To Avoid.
Strengths and Forms
This product is an oral tablet. Availability can vary by manufacturer and market. Commonly dispensed options may include a low-dose presentation such as Cytomel 5 mcg; your prescriber will determine the appropriate choice for your situation.
Packaging and imprint details can differ. Pharmacy selection can influence which brand or generic presentation is supplied. If a particular tablet size or appearance matters for your routine, discuss this with your prescriber and pharmacist.
Missed Dose and Timing
If you forget a dose, take it when you remember the same day. If it is close to the next scheduled dose, skip the missed one and resume your regular schedule. Do not double up. Keeping a daily reminder can help maintain consistency.
If multiple doses are missed, contact your healthcare professional for guidance. Thyroid hormone is a long-term therapy, and steady use helps maintain stable lab values and symptom control.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from excess heat and light. Keep the bottle tightly closed and out of reach of children and pets. Do not store in a bathroom where humidity is high.
When traveling, keep your supply in your carry-on. Bring your prescription label and a small buffer in case of schedule shifts. If crossing borders, you can carry supporting documentation. For best results, take each daily dose consistently. If your clinician provided special instructions, follow those directions.
Benefits
Thyroid hormone replacement helps restore metabolic balance when the body cannot produce enough T3. Patients may notice support for energy, temperature regulation, and cognitive function as levels normalize.
Oral therapy provides straightforward daily use. Tablet dosing allows individualized titration based on clinical response and lab testing. This medicine can be combined with other thyroid agents when appropriate and directed by a prescriber.
Side Effects and Safety
- Headache or irritability
- Nervousness or tremor
- Palpitations or fast heartbeat
- Increased sweating
- Diarrhea
- Sleep disturbances
Serious effects can occur with overtreatment or in sensitive patients, including chest pain, arrhythmias, shortness of breath, and signs of thyrotoxicosis. Bone loss risk may increase with sustained excessive dosing. Seek urgent care for severe chest pain, fainting, or severe shortness of breath.
Thyroid hormone can alter blood glucose control. Insulin or sulfonylurea doses may require adjustment under clinical oversight. If you use diabetes therapies, monitor closely and inform your prescriber about changes in symptoms.
Learn about common thyroid-related experiences from another therapy’s perspective here: Synthroid Side Effects.
Drug Interactions and Cautions
Separate thyroid hormone from binding agents such as calcium carbonate, iron salts, aluminum or magnesium antacids, bile acid sequestrants, and certain phosphate binders. Some anticonvulsants, rifampin, and sertraline can affect hormone levels. Amiodarone and iodinated contrast agents can influence thyroid function and may require monitoring.
Anticoagulants can have enhanced effects with thyroid hormone, and diabetes medications may need changes under medical supervision. Always share a complete medication and supplement list with your prescriber and pharmacist.
Comparative information across therapies can be useful when discussing options: Synthroid vs Levothyroxine.
What to Expect Over Time
Thyroid replacement works gradually as levels are stabilized. A clinician will typically order periodic labs and adjust the plan as needed. Consistent daily use, timing, and separation from interfering supplements help keep values stable.
Symptom changes can vary. Some people feel improvements as hormone levels normalize, while others notice subtler changes over longer periods. Communicate any new symptoms to your healthcare professional and attend scheduled follow-ups.
Compare With Alternatives
Levothyroxine (T4) remains first-line for many patients. However, for specific clinical reasons, liothyronine may be considered. Some prescribers also use combination T4/T3 approaches in select cases based on clinical judgment and monitoring.
We carry multiple thyroid options. T4-only choices include Eltroxin and Thyro Tab. Discuss with your prescriber which approach aligns with your diagnosis and lab results.
Pricing and Access
Canadian-sourced therapies can offer value. If you are comparing options, review the Cytomel price alongside any generic listings available to your prescriber. We provide clear checkout, encrypted processing, and transparent product details. For occasional site offers, visit Promotions.
We support fulfillment that Ships from Canada to US and provide order updates by email. For regional sourcing details, see the product attribute page for Canada. If you have questions about availability or substitutions, our team can explain options for your prescriber’s consideration.
Availability and Substitutions
Supply can vary by manufacturer and market. If a specific brand is unavailable, a prescriber may recommend a therapeutically appropriate alternative. Some patients use levothyroxine-based options when T3 is not required.
Ask about comparable choices such as Apo Levothyroxine or desiccated Thyroid Tablets if suitable. All substitutions must be directed by your prescriber and verified by the dispensing pharmacist.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults and children with documented hypothyroidism when T3 is indicated. It may not be appropriate for people with uncorrected adrenal insufficiency or certain cardiac conditions. A thorough history, exam, and labs guide treatment decisions.
To manage costs, consider multi-month supplies when clinically appropriate. Set refill reminders so you do not run out. If you travel, carry a little extra in your hand luggage and keep the labeled bottle with you. Consistent timing and separation from interfering supplements can reduce waste from dose fluctuations and repeat lab visits.
Questions to Ask Your Clinician
- Diagnosis and goals: Which labs confirm my thyroid status, and what is the target range?
- Treatment choice: Why T3, T4, or a combination for my situation?
- Administration: How should I time doses with meals, calcium, or iron?
- Monitoring: How often will labs be checked initially and long term?
- Safety: What symptoms suggest overtreatment or undertreatment?
- Interactions: Which medicines or supplements should I separate or avoid?
- Pregnancy plans: How will management change if I become pregnant?
Authoritative Sources
FDA DailyMed: Liothyronine Sodium Tablets
Manufacturer: Cytomel (Pfizer)
Health Canada: Cytomel Product Monograph
Ready when your prescription is? Order Cytomel with prompt, express shipping and US shipping from Canada. Always use as directed by your prescriber; this page is informational and not a substitute for medical advice.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
How is liothyronine different from levothyroxine?
Liothyronine is synthetic T3, the active thyroid hormone. Levothyroxine is T4, which the body converts to T3. Many people do well on T4 alone. Some patients, under clinician guidance, use T3 when T4 is not suitable or when a different approach is needed. The choice depends on diagnosis, symptoms, lab values, and medical history. Your prescriber will determine which therapy, or combination, fits your case and will adjust based on response and tests.
Can I take liothyronine with coffee, calcium, or iron?
Coffee, calcium, iron, and some antacids can reduce absorption if taken close to your dose. Many clinicians suggest taking thyroid medicine on an empty stomach with water and separating it from those products by several hours. Follow your prescription label and your clinician’s instructions. If timing is difficult, discuss a practical schedule to keep dosing consistent and support stable thyroid levels over time.
What monitoring is usually needed with liothyronine?
Thyroid function tests guide therapy decisions. A clinician typically orders labs after dose changes and periodically to ensure levels are appropriate. Frequency depends on individual factors, including age, cardiac status, and symptoms. Let your prescriber know about new medicines or supplements, as they can affect lab results. Do not change your dose on your own; adjustments should be supervised based on labs and clinical assessment.
What if I feel over-replaced or under-replaced on treatment?
Symptoms of too much thyroid hormone can include palpitations, anxiety, sweating, and trouble sleeping. Too little may cause fatigue, cold intolerance, and constipation. Keep a simple symptom log and report changes to your clinician. Do not add or stop doses without direction. Your prescriber may adjust the plan after reviewing labs, your history, and concurrent medicines to maintain a safe and effective regimen.
Can liothyronine affect heart conditions or bone health?
Excess thyroid hormone can strain the heart and contribute to bone loss, especially with long-term overtreatment. People with coronary disease, arrhythmias, or risk factors require careful evaluation and monitoring. Your prescriber will tailor dosing to your situation, adjust gradually when needed, and watch for symptoms and lab changes. Report chest pain, severe shortness of breath, or fainting immediately. Discuss bone health measures if you have risk factors.
What should I do if I miss a dose?
If you miss a dose, take it when you remember the same day. If it is near the next scheduled dose, skip the missed dose and resume your normal schedule. Do not double up. Consistent timing helps maintain stable thyroid levels. If you miss more than one dose, contact your healthcare professional for guidance. Setting reminders or pairing dosing with a daily routine can help reduce missed doses.
Are there interactions I should know about?
Calcium, iron, aluminum or magnesium antacids, and bile acid sequestrants can bind thyroid hormone in the gut and reduce absorption. Some medicines, such as certain anticonvulsants, sertraline, and rifampin, may change how your body processes the hormone. Warfarin and diabetes medicines can require closer monitoring. Share a full list of medicines and supplements with your prescriber and pharmacist, and ask about timing to avoid conflicts.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
How to book an appointment
- 1Create Begin by completing a profile or log into your existing account. This step ensures we have the necessary information to provide you with a service that's tailored to your needs. account and start earning.
- 2Scheduling an appointment with our online booking system is easy. Pick a day and time that suits you. You’ll receive an immediate confirmation, without the wait.
- 3Discuss your concerns and symptoms and receive a thorough diagnosis from one of our licensed doctors during a confidential video appointment.
- 4If you've been prescribed medication, your Rx is sent directly to one of our licensed pharmacies and delivered right to your door.
Get Started
To book an online doctor appointment, register for an account or login. After doing so, you can book your visit on this page.
