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Dexilant® Delayed-Release Capsules for GERD
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Dexilant® is a prescription proton pump inhibitor used for GERD and erosive esophagitis. This page helps you compare strengths, uses, and access options with US shipping from Canada. If you pay cash, you can explore Dexlansoprazole without insurance and learn what to discuss with your prescriber.
What Dexilant Is and How It Works
This medicine contains dexlansoprazole, a dual delayed‑release proton pump inhibitor. It reduces stomach acid by blocking the acid pumps in the stomach lining. The treatment can help relieve heartburn, allow the esophagus to heal, and support maintenance after healing. It may be taken with or without food.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
The capsule uses two release phases. The first phase starts reducing acid soon after ingestion. The second phase helps extend acid control later in the day. This design can support symptom control across the dosing interval.
Learn more about the condition and treatment journey in our guides on Acid Reflux and GERD. For general background, see Gastroesophageal Reflux Disease.
Who It’s For
This therapy is used for healing of erosive esophagitis, maintenance of healed erosive esophagitis with continued relief of heartburn, and treatment of heartburn associated with gastroesophageal reflux disease. It is approved for adults and certain adolescents when indicated on the official label.
People with known hypersensitivity to dexlansoprazole, substituted benzimidazoles, or any capsule component should avoid it. Acid-reducing agents can affect drugs where gastric pH is critical; rilpivirine is contraindicated with proton pump inhibitors. Discuss liver problems, bone health, or low magnesium history with a healthcare professional before starting.
For practical reading on symptoms and care, visit Erosive Esophagitis and our category for Gastrointestinal treatments.
Dosage and Usage
Follow your prescriber’s directions and the approved label. Typical regimens include once-daily dosing for healing, maintenance after healing, or relief of heartburn. The capsule can be taken regardless of meals. Swallow whole, or when permitted by the label, open the capsule and sprinkle its contents on applesauce for immediate consumption. If an oral syringe or nasogastric route is needed, defer to the official instructions for preparation and flushing steps.
Do not crush or chew the granules. Take the dose at the same time each day to support routine. If you are switching from another acid reducer, your clinician will guide timing. For condition education and non-drug tips, see our article Costs Without Insurance for planning broader care needs.
Strengths and Forms
The product is supplied as delayed-release capsules in two strengths. Availability may vary by pharmacy and manufacturer.
- Dexlansoprazole 60 mg capsules
- 30 mg capsule option for appropriate indications
Images, imprints, and pack sizes can differ by source. Your final dispensed item may not match online images.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. If it is close to the next dose, skip the missed one and resume the regular schedule. Do not double up to make up for a forgotten dose. Consistent daily timing can help with symptom control.
Storage and Travel Basics
Store capsules at room temperature in a dry place, away from moisture and light. Keep in the original labeled container with the desiccant, and tightly close the cap after each use. Do not use past the expiration date. Keep out of reach of children and pets.
When traveling, carry the medication in your hand luggage. Bring a copy of your prescription or a pharmacy label. If you use a weekly pill organizer, also carry a portion of the medication in the original bottle for documentation. Security screening does not usually affect the capsule.
Benefits
As a proton pump inhibitor, this therapy can reduce acid exposure and help heal erosive injury where indicated. The dual delayed-release design may extend control across the day. Many people appreciate that it can be taken with or without food, which simplifies schedules. Maintenance regimens can help prevent symptom recurrence after healing.
Side Effects and Safety
- Headache
- Diarrhea
- Abdominal pain
- Nausea or vomiting
- Gas or bloating
- Upper respiratory symptoms
Serious risks are uncommon but can occur. These include Clostridioides difficile–associated diarrhea, low magnesium, vitamin B12 deficiency with long-term use, bone fracture risk with prolonged high-dose therapy, lupus erythematosus cutaneous reactions, and acute interstitial nephritis. Seek urgent care for severe rash, persistent diarrhea, muscle cramps, seizures, or signs of allergic reaction. The label also notes potential fundic gland polyps with chronic use.
Drug Interactions and Cautions
Acid suppression can reduce the absorption of medications that require a low gastric pH. Rilpivirine is contraindicated; atazanavir, nelfinavir, and certain antifungals or tyrosine kinase inhibitors may be affected. Separate administration guidance may not overcome PPI effects for some agents.
Use caution with high-dose methotrexate, as PPIs may increase exposure. Monitor with digoxin and consider magnesium status. Dexlansoprazole is metabolized by CYP2C19 and CYP3A4; clinically meaningful interactions are limited, but individual variability exists. Warfarin monitoring is prudent when starting or stopping PPIs. Always provide a full medication list to your prescriber.
For comparative therapy context, read Cimetidine Dosage or our piece on Famotidine 20 mg.
What to Expect Over Time
Heartburn relief may begin after the first few doses, and healing typically requires consistent daily use as directed on the label. Some people need a maintenance dose to prevent relapse after erosive disease heals. If symptoms persist or return, speak with your clinician to reassess diagnosis, dosing, or lifestyle measures. Adherence, trigger food management, and timing relative to meals can influence outcomes for acid-related conditions.
Compare With Alternatives
Proton pump inhibitors share a similar mechanism but differ in release profiles and dose options. Some patients start with omeprazole or esomeprazole and switch based on response or tolerability. If you and your prescriber are evaluating options, you can also review Omeprazole or Esomeprazole on our site.
Pricing and Access
Canadian pharmacy channels can offer favorable pricing compared with many local cash rates. We display current options so you can review formulary status and compare products. For reference shopping, some patients look up Dexlansoprazole price on our product pages while considering alternatives.
We also provide context on payer coverage and generics when available. This helps you weigh brand versus non-brand choices and plan refills. While comparing options, people sometimes check Dexlansoprazole generic price to understand longer-term budgets. We arrange fulfilment that Ships from Canada to US when permitted.
If you are seeking coupon opportunities, see current Promotions for site-wide offers that may apply at checkout.
Availability and Substitutions
Supply can vary. If this item is unavailable, a prescriber may recommend a therapeutic alternative in the same class. Pharmacists cannot substitute unless your prescription and state laws allow it. When an authorized generic is listed, some patients explore Generic Dexilant to compare packaging and labeler details.
For condition education and therapy comparisons, you can also read Generic Alternatives and browse treatments by Canada sourcing.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults and certain adolescents who need acid reduction for labeled indications. It may not suit people with prior severe hypersensitivity to PPIs, those on rilpivirine, or those with conditions where reduced stomach acid is undesirable. Share your medical history, including kidney issues, osteoporosis risk, or prior C. difficile infection, with your clinician.
Cost-wise, compare multi-month fills to reduce per-fill fees. Set reminders so you do not miss doses or refills. Check insurance coverage tiers and ask about step therapy. People who shop cash sometimes search for a Dexilant coupon; pairing a site promotion with Canadian pricing can help.
Questions to Ask Your Clinician
- Diagnosis fit: Is GERD or erosive esophagitis confirmed?
- Therapy aim: Healing, maintenance, or symptom control?
- Dose plan: How long should I stay on the current schedule?
- Monitoring: Which symptoms or labs should we track?
- Interactions: Any conflicts with my current medicines?
- Alternatives: If this is not suitable, which PPI or H2 blocker next?
Authoritative Sources
FDA Prescribing Information | Health Canada DPD | Manufacturer Site
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How is this PPI different from others?
Dexlansoprazole uses a dual delayed‑release design, which releases part of the dose soon after ingestion and another portion later. This can extend acid control across the day versus some PPIs with a single release profile. Actual results vary by patient and indication. Your clinician can help decide if this release pattern fits your symptom pattern and treatment goals.
Can I take it with food or at night?
It can be taken with or without food according to the approved label. Try to take it at the same time daily. Some people take it in the morning, others in the evening based on symptom patterns. If symptoms persist, speak with your prescriber about timing strategies that align with the label and your routine.
How long do people usually stay on therapy?
Healing courses are typically limited in duration, while maintenance for healed erosive disease may continue longer at a lower dose if appropriate. The plan depends on diagnosis, response, and risk factors. Your prescriber will tailor the duration. Do not change or stop the medicine without medical guidance.
What side effects should I watch for?
Common effects include headache, diarrhea, abdominal pain, nausea, gas, and upper respiratory symptoms. Serious risks are uncommon but include C. difficile–associated diarrhea, low magnesium, B12 deficiency with long-term use, cutaneous lupus, interstitial nephritis, and bone effects. Seek care for severe rash, persistent diarrhea, muscle cramps, seizures, or allergic reactions.
Are there important drug interactions?
Acid suppression can significantly affect medications that require low gastric pH. Rilpivirine is contraindicated with PPIs; drugs like atazanavir, certain antifungals, and some TKIs may be impacted. Use caution with high-dose methotrexate and digoxin, and provide a full medication list so your prescriber can assess risks.
What if I miss a dose?
Take it when you remember unless it is almost time for the next one. If the next dose is near, skip the missed dose and resume your normal schedule. Do not take two doses together to make up for a missed dose. Keeping a daily reminder can help prevent missed doses.
How should I store and travel with it?
Store at room temperature in a dry place away from moisture and light. Keep it in the original, labeled container and out of reach of children. For travel, pack it in carry-on bags with a copy of your prescription or pharmacy label. Avoid storing it in hot cars or damp bathrooms.
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