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Diltiazem Tablets for Hypertension and Angina
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Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
Price range: $64.99 through $122.99
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This calcium channel blocker treats high blood pressure and chest pain from reduced blood flow. BorderFreeHealth offers US shipping from Canada, helping you compare options without insurance. Use this guide to understand uses, dosing basics, safety, and how to store your medicine.
What Diltiazem Is and How It Works
This medicine is a non-dihydropyridine calcium channel blocker. It relaxes coronary and peripheral blood vessels and slows conduction through the heart’s AV node. The result can be lower blood pressure, less angina, and controlled heart rate in certain supraventricular rhythms. Many people start with Diltiazem 30mg tablets when immediate-release dosing is prescribed. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
By reducing the heart’s workload and oxygen demand, the treatment may ease exertional chest discomfort. It can also support rate control in atrial arrhythmias when used as directed by a clinician.
Who It’s For
This therapy is used for adults with diagnosed high blood pressure and chronic stable or vasospastic angina. Clinicians also use it for rate control in certain supraventricular tachycardias and atrial fibrillation. Some patients who previously used Cardizem 60 mg may be transitioned to comparable generic regimens under medical supervision. See our condition guides on Hypertension, Angina, and Atrial Fibrillation for context.
People with severe low blood pressure, sick sinus syndrome or AV block without a pacemaker, acute decompensated heart failure, or known hypersensitivity should avoid this medicine. Always review your cardiac history and current drugs with your prescriber.
Dosage and Usage
Immediate-release schedules are typically multiple times daily, while extended-release products are usually once daily. Follow the exact instructions on your prescription label. When immediate-release is used, a clinician may begin with lower doses and adjust gradually. Some patients stabilize on Diltiazem 120 mg, though the correct dose is individualized. Do not crush or chew extended-release capsules or tablets.
Take it at the same time each day. Swallow with water. If stomach upset occurs, a light meal may help. Avoid grapefruit or grapefruit juice unless your clinician says otherwise due to potential interaction.
Strengths and Forms
Available forms include immediate-release tablets and extended-release capsules or tablets. Common strengths include 30 mg, 60 mg, 90 mg, 120 mg for immediate-release, and 120 mg, 180 mg, 240 mg, 300 mg, and 360 mg for many extended-release products. Some patients may be prescribed Diltiazem CD 240 mg when a once-daily capsule is appropriate. Specific brands and strengths can vary by manufacturer and by market.
Availability may change over time. Your prescriber may select a formulation that matches your daily schedule and clinical targets.
Missed Dose and Timing
If you miss a dose, take it when you remember the same day. If it is close to your next dose, skip the missed dose and take the next one at the regular time. Do not double up. Keeping a simple reminder system can help you stay on track.
Storage and Travel Basics
Store at room temperature in a dry place away from moisture. Keep the medicine in its original container and out of reach of children and pets. When traveling, carry it in your hand luggage with a copy of your prescription. If your itinerary crosses time zones, keep consistent intervals based on your home schedule until you can confirm a new routine with your clinician. Pharmacies use temperature-controlled handling when required. Avoid storing tablets in a car glovebox or direct sunlight.
Benefits
This therapy can lower blood pressure, reduce angina frequency, and help control heart rate in certain supraventricular rhythms. Extended-release options simplify dosing to once daily for many patients. Stable blood pressure and rate control can support exercise tolerance and daily functioning when combined with lifestyle measures recommended by your healthcare professional.
Side Effects and Safety
- Headache or dizziness, especially when starting
- Flushing or feeling warm
- Swelling of ankles or feet
- Constipation or stomach upset
- Fatigue
Serious reactions are less common but require prompt medical attention. These include slow heart rate, fainting, severe low blood pressure, worsening heart failure, or signs of liver issues such as dark urine or yellowing skin. Seek urgent care for chest pain that changes in pattern or intensity. Risk of low blood sugar may increase when used with insulin or sulfonylureas in people with diabetes due to reduced clearance of some agents; monitoring may be advised by your clinician.
Drug Interactions and Cautions
This medicine can interact with beta-blockers, digoxin, certain statins, cyclosporine, carbamazepine, and drugs metabolized by CYP3A4. Alcohol may intensify blood pressure lowering. Avoid grapefruit products unless approved by your prescriber. If you take anticoagulants such as Warfarin, discuss coordination of care, as clinical monitoring plans can overlap. Learn about related calcium channel blockers in Verapamil Uses.
Tell your clinician about all medicines, vitamins, and herbal supplements. Provide an up-to-date list at each visit and pharmacy fill.
What to Expect Over Time
Blood pressure improvements may appear gradually with steady daily use. Angina symptoms may become less frequent when activity triggers are consistent and the regimen is maintained. For rhythm control, your prescriber may pair this therapy with additional medications or procedures. Keep scheduled follow-ups and lab checks if ordered. Using a home blood pressure log can help your prescriber judge effectiveness and tolerability.
Report new swelling, dizziness, or unusual fatigue. Do not stop abruptly without clinical guidance, as symptoms can rebound in some people.
Compare With Alternatives
Other calcium channel blockers may be considered if you need a different profile. Long-acting nifedipine options such as Nifedipine Xr or brand formulations like Adalat® Xl can be appropriate for some patients. Beta-blockers may be used instead or alongside, depending on your condition and clinician guidance.
Pricing and Access
See current Diltiazem price and compare supply sizes before you add to cart. Canadian pricing is often competitive for US patients. We provide transparent options with a secure checkout experience. Orders Ships from Canada to US after your prescription is verified. If you are looking for seasonal offers, check our Promotions. Explore related heart medicines in our Cardiovascular section.
Availability and Substitutions
Stock can vary by strength and manufacturer. If a specific item such as Diltiazem 360 mg is unavailable, your prescriber may recommend a therapeutically appropriate alternative dose or a different extended-release brand. Pharmacists will dispense the exact item on your prescription or contact your prescriber for guidance if a substitution is needed.
Patient Suitability and Cost-Saving Tips
Good candidates can take this therapy reliably, monitor for dizziness, and follow up for dose adjustments. People with advanced conduction disease without a pacemaker or severe hypotension are generally not candidates. To reduce costs, consider multi-month fills if your prescriber agrees, and align refills with routine checkups. Set phone reminders for daily dosing to avoid last-minute urgent requests. Review heart-health articles such as Angina Symptoms to support lifestyle planning.
If your plan changes, talk with your clinician before switching forms. For rate control or blood pressure, beta-blockers like Nadolol or Atenolol may be considered based on your history.
Questions to Ask Your Clinician
- Is immediate-release or extended-release better for my routine?
- How should I monitor blood pressure and heart rate at home?
- Do I need lab tests to check kidney or liver function?
- What symptoms mean I should call your office promptly?
- Could my other medicines raise levels of this treatment?
- How should I coordinate timing with other heart therapies?
- Are there activity or diet changes that complement this therapy?
Authoritative Sources
For full prescribing details, see official resources:
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Can Diltiazem be used to treat arrhythmias?
Yes, Diltiazem is used to manage certain types of heart rhythm problems, particularly atrial fibrillation or flutter.
Does Diltiazem affect exercise performance?
It may reduce exercise tolerance in some patients by slowing heart rate. Talk to your doctor if you notice significant changes in endurance.
How long does it take for Diltiazem to work?
Blood pressure effects usually appear within a few hours. It may take several days to see the full benefit on chest pain or heart rate.
Is it safe to consume grapefruit while taking Diltiazem?
No, grapefruit can increase the blood levels of Diltiazem, raising the risk of side effects. Avoid grapefruit and its juice.
Can Diltiazem cause weight gain?
Some people may experience fluid retention, leading to temporary weight gain. Notify your doctor if you experience unexplained weight changes.Can I switch between immediate-release and extended-release forms?
Switching between forms should be guided by your prescriber. Immediate-release is taken multiple times a day, while extended-release is usually once daily. The total daily amount and how your body absorbs it can differ between forms. Do not crush or split extended-release versions. If your schedule or side effects make your current form hard to manage, ask your clinician whether a different formulation could help and how to transition safely.
Can I drink grapefruit juice while taking this medicine?
Grapefruit and grapefruit juice can change how some drugs are metabolized, including this therapy. The effect can raise blood levels and increase side effects such as dizziness or swelling. It is safest to avoid grapefruit products unless your prescriber confirms they are acceptable for you. Other citrus fruits like oranges typically do not have the same interaction, but always follow individualized medical advice.
What if I feel dizzy after starting treatment?
Dizziness can occur, especially when you first start or when your dose changes. Stand up slowly from sitting or lying positions. Track your blood pressure and heart rate as instructed. If dizziness is persistent, worsening, or associated with fainting, contact your clinician. They may adjust timing, review other medications, or consider a different option. Avoid driving or operating machinery until you know how the medicine affects you.
Is it safe to combine this drug with beta-blockers?
Combining with beta-blockers can be appropriate in some cases but needs close supervision. Both slow AV nodal conduction and can lower heart rate and blood pressure, increasing the risk of bradycardia or hypotension. Your clinician will decide if the benefits outweigh risks and will outline monitoring. Report symptoms such as lightheadedness, fatigue, or shortness of breath promptly. Never start or stop heart medicines without professional guidance.
Can I cut or crush my tablets?
Do not crush or chew extended-release versions, as that can release the dose too quickly. Immediate-release tablets may be scored for splitting, but only do so if your prescriber or pharmacist confirms it is appropriate for your specific product. Use a proper tablet splitter for accuracy. If swallowing is difficult, ask about different formulations that match your prescribed regimen.
How long until I notice benefits?
Some people notice changes in blood pressure within days, while others require gradual adjustments. Angina frequency may decrease with steady use and activity pacing. There is no single timeline because response varies with dose, form, and other therapies. Keep a simple symptom and blood pressure log, and share it during follow-up. Your clinician will decide if changes are needed to meet treatment goals.
What monitoring might my clinician recommend?
Your clinician may check blood pressure, heart rate, and potentially ECGs, especially if rhythm control is a goal. They may also review kidney and liver function, depending on your health status and other medicines. Home readings are helpful. Bring an updated medication list to each visit. Report swelling, constipation, new fatigue, or changes in chest discomfort so your plan can be adjusted safely.
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