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Intelence
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Intelence (etravirine) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV in combination with other antiretroviral medications.
Benefits:
- It helps reduce HIV viral load and improves immune function.
- Used in combination therapy for resistant HIV strains.
- It can be taken with or after a meal for better absorption.
Dosage:
- Typically taken twice daily with food.
- Dosage may vary depending on treatment regimen.
Warnings and Precautions:
- It is not a cure for HIV; it must be used as part of combination therapy.
- It may cause skin reactions or hypersensitivity.
- Regular liver function tests may be required.
Usage Instructions:
- Take with food to enhance absorption.
- Swallow tablets whole; do not crush or chew.
- Do not skip doses to prevent drug resistance.
Storage Information:
- Store at room temperature, away from moisture and heat.
Common Side Effects:
- Mild: Nausea, rash, headache.
- Severe: Severe allergic reactions, liver toxicity, fever (seek medical attention immediately).
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Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
What is Intelence used for?
Intelence (etravirine) is an antiretroviral medication used in combination with other drugs to treat HIV-1 infection in adults and children. It belongs to the class of drugs called non-nucleoside reverse transcriptase inhibitors (NNRTIs), which help block the replication of HIV. Intelence is typically prescribed when resistance to other NNRTIs has developed. While it does not cure HIV or AIDS, it helps reduce the viral load and maintain immune system function.
How does Intelence work in HIV treatment?
Intelence works by binding to the reverse transcriptase enzyme of the HIV, interfering with its ability to replicate. Doing this reduces the number of active viruses in the body and helps the immune system function more effectively. This mechanism is particularly beneficial for patients who have previously failed other NNRTI-based therapies. Effective viral suppression also reduces the risk of HIV-related complications and transmission.
How should I take Intelence?
Intelence is usually taken twice daily after meals to improve absorption. The tablets should be swallowed whole with liquid, but if swallowing is difficult, they can be dispersed in water and consumed immediately. It’s essential to take the medication consistently at the exact time each day to maintain stable drug levels. Skipping doses or inconsistent intake may lead to drug resistance and treatment failure.
What precautions should I take while using Intelence?
Inform your doctor if you have liver disease, particularly hepatitis B or C, as this may affect your treatment. Intelence may interact with several medications, including antiepileptics, antifungals, and other HIV drugs, so a complete medication review is necessary. Do not use Intelence as monotherapy; it must be part of a combination regimen. Women who are pregnant or breastfeeding should consult their doctor due to limited data on safety in these populations.
What are the common side effects of Intelence?
Side effects may include rash, nausea, diarrhea, and fatigue. Although rare, severe skin reactions, such as Stevens-Johnson syndrome, have been reported and require immediate medical attention. Changes in liver enzymes and lipid levels may also occur, requiring regular monitoring. Always report new or worsening symptoms to your healthcare provider promptly.
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