Nifedipine XR® Tablets for Hypertension and Angina

Nifedipine XR is an extended-release calcium channel blocker used for high blood pressure and chronic angina. You can access US delivery from Canada through our platform. This page outlines how the medicine works, usage basics, safety, and ways to manage costs if you pay without insurance.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

What Nifedipine XR Is and How It Works

Nifedipine XR® lowers blood pressure and helps prevent chest pain by relaxing blood vessel smooth muscle. The treatment reduces peripheral vascular resistance, which can lower the heart’s workload. It belongs to the dihydropyridine class of calcium channel blockers. This class primarily acts on arterial vasodilation rather than heart rate control. The extended-release form provides steady levels over 24 hours.

For hypertension, this medicine helps lower readings and supports long-term cardiovascular risk reduction as part of a broader plan. For chronic stable or vasospastic angina, it can decrease the frequency of episodes. Use only as directed by your prescriber and follow the approved label.

Who It’s For

This therapy is used in adults for the treatment of high blood pressure and for chronic stable or vasospastic angina as directed. It is not for rapid relief of acute chest pain. People with a known allergy to nifedipine should not take it. Those with severe aortic stenosis, recent heart attack, or unstable angina need careful evaluation before use. Individuals with significant liver impairment may require closer monitoring. Discuss use during pregnancy or breastfeeding with a clinician.

Dosage and Usage

Follow your prescriber’s directions and the official label. Extended-release tablets are taken once daily at the same time each day. Swallow tablets whole with water. Do not crush, chew, or split. Taking it consistently with or without food can help maintain predictable absorption. Avoid grapefruit and grapefruit juice because they can change drug levels. If your regimen includes other blood pressure medicines, your clinician may monitor for additive effects during initiation or changes.

Do not stop therapy suddenly unless your prescriber advises it. Periodic blood pressure checks at home and in clinic may be recommended. Report new or worsening chest pain promptly. If you notice persistent swelling in the ankles or flushing that does not settle, share this with your healthcare professional.

Strengths and Forms

Extended-release tablets are commonly available in several strengths. Availability can vary by manufacturer and supply. Typical presentations include 30 mg, 60 mg, and sometimes 90 mg tablets. Manufacturers and trade names may differ by market; some supplies are labeled by companies like Mylan Nifedipine XR. Your final product may differ in packaging appearance while meeting the same active ingredient and release profile as authorized.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is close to your next scheduled dose. If it is almost time for the next dose, skip the missed dose and resume your usual schedule. Do not double up. Setting alarms or using a pill organizer can support steady, day-to-day adherence.

Storage and Travel Basics

Store tablets at room temperature in a dry place and keep the bottle tightly closed. Protect from excessive moisture and light. Keep out of reach of children and pets. When traveling, carry your medicine in original labeled packaging in your hand luggage with a copy of your prescription. Time-zone changes can usually be managed by taking your daily dose at your usual home-time until you comfortably shift to the local schedule. If security checks require inspection, keep the label visible to avoid delays. Temperature-controlled handling when required is supported by our partners for suitable products.

Pen Handling and Sharps Disposal

This therapy is supplied as oral extended-release tablets. No injection devices or sharps are involved, so needle handling does not apply.

Benefits

The class can help reduce blood pressure over time, which may lower strain on the heart and blood vessels. Once-daily dosing supports steady coverage across the day and night. For chronic angina, fewer episodes may occur when the regimen is optimized. As a long-used medicine, nifedipine has extensive clinical experience and multiple generic manufacturers, which may support broader access.

Side Effects and Safety

• Headache or flushing, usually mild
• Dizziness or lightheadedness
• Peripheral edema, especially ankles
• Fatigue or weakness
• Nausea or stomach discomfort
• Palpitations

Serious effects are uncommon but can include significant hypotension, worsening angina, or rare cardiac events in susceptible patients. Gingival overgrowth and liver enzyme changes have been reported. Seek medical help for chest pain that is new, severe, or different from usual; fainting; allergic reactions; or persistent swelling with shortness of breath. If you also use insulin or sulfonylureas, monitor for dizziness from low pressure that could be confused with low glucose symptoms.

Drug Interactions and Cautions

Strong CYP3A inhibitors (for example, certain azole antifungals, macrolide antibiotics, or protease inhibitors) may raise levels and the risk of side effects. Strong CYP3A inducers (like rifampin or some anticonvulsants) may reduce effectiveness. Grapefruit and grapefruit juice can increase exposure and should be avoided. Other blood pressure treatments, nitrates, or alpha-blockers may produce additive blood pressure lowering. Monitor if taken with digoxin or other narrow-therapeutic-index agents per your prescriber’s guidance. Alcohol can increase dizziness. Always share a complete medication list, including over-the-counter products and supplements, with your clinician.

What to Expect Over Time

Blood pressure generally improves with consistent daily use, supported by lifestyle changes recommended by your care team. Angina episodes may become less frequent as the dose is optimized under medical supervision. Some early effects like flushing or mild dizziness often ease after the first days. Keep a simple log of blood pressure and any chest pain patterns to discuss during follow-ups. If your clinician adjusts therapy, they may allow time between changes to observe response and tolerability.

Compare With Alternatives

Other long-acting calcium channel blockers can be suitable if your prescriber recommends a switch. A brand formulation of nifedipine extended-release is Adalat XL, which some patients use under clinician guidance. A beta-blocker such as Atenolol may be suggested for specific heart-rate or angina needs. Your clinician will consider your history, other medicines, and goals when selecting the best option.

Pricing and Access

Our platform highlights Nifedipine XR price so you can compare options clearly. We display transparent details and note when generics may offer better value. You get the same active ingredient and extended-release profile when supplied by approved manufacturers. US delivery with our partners keeps access straightforward for ongoing therapy. We also present Nifedipine XR Canadian pricing to reflect the sourcing channel. If you are looking for current deals, see our Promotions page. Checkout uses encrypted processes to protect your information.

Availability and Substitutions

Occasional supply shifts can occur due to manufacturer changes or market dynamics. If a specific strength or count is temporarily unavailable, your prescriber may recommend an appropriate alternative or equivalent. Packaging and tablet imprint can vary by manufacturer. We indicate the country of origin when relevant to the listing and maintain clear labeling to avoid confusion.

Patient Suitability and Cost-Saving Tips

This therapy suits many adults with hypertension or chronic angina when prescribed by a clinician. People with severe aortic stenosis, unstable symptoms, or recent myocardial infarction need individualized decisions. If you have liver impairment, extra monitoring may be required.

• Multi-month refills: lowers per-fill costs and reduces trips
• Consistent timing: improves control and reduces waste
• Use one pharmacy: helps check interactions quickly
• Track readings: share trends to avoid unnecessary changes
• Talk with prescriber: consider generics where appropriate

Category browsing can help you find related options that might fit your plan. See Hypertension and Angina for condition-specific listings, and explore Cardiovascular treatments. For origin details, view Canada on eligible items. To learn more about related heart topics, read Angina Symptoms or explore Verapamil Uses.

Questions to Ask Your Clinician

• Is an extended-release calcium channel blocker right for my goals?
• How should I time doses with other heart medicines?
• What side effects should I watch for in the first weeks?
• Do my other prescriptions or supplements interact with this therapy?
• How often should I check blood pressure at home?
• What are my options if swelling or flushing persists?
• Would another agent be better for my angina pattern?

Authoritative Sources

FDA DailyMed: Nifedipine Extended-Release Tablets

Health Canada DPD: Nifedipine

Manufacturer Information: Adalat (nifedipine)

Ready to continue? For savings and reliable access, order Nifedipine XR online with prompt, express shipping and US shipping from Canada. This content is educational and not a substitute for professional medical advice. Always follow your prescriber’s directions.