Please note: a valid prescription is required for all prescription medication.
Retino-A® Cream for Acne
Buy more, save more: Get 20% off when you buy 3 or more of any one product. Use code LESS20 at checkout.
Coupon code cannot be combined with other offers. Sale applies to all products originating from Canada. Maximum allowable quantity equal to a 90 day supply per single order.
$35.99
Secure Encrypted Payments
Retino-A® Cream is a topical retinoid used for acne and texture concerns. It supports skin turnover to help clear pores and smooth roughness. This page explains key facts so you can compare options and arrange US delivery from Canada. If you pay cash, you can consider Retino-A Cream without insurance as part of your choices.
What Retino-A Is and How It Works
Topical tretinoin is a vitamin A derivative that increases cell turnover on the skin’s surface. It helps prevent new comedones and can reduce the look of uneven tone over time. Many clinicians use this class as a baseline therapy for persistent breakouts and photoaging concerns.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This medicine acts inside the follicle to keep dead skin and oil from forming plugs. You typically use a small amount at night, then moisturize to balance dryness. For guidance on acne basics, see Acne and discuss goals with your prescriber before starting the cream.
After establishing tolerability, many people continue the treatment as part of a routine. Results depend on consistent use, sun protection, and the severity of your skin concerns.
When considering options for texture or sun damage, explore related care topics such as Photoaging and Dermatology.
Over time, Retino-A Cream may be layered with gentle cleansers, fragrance-free moisturizers, and broad-spectrum sunscreen for support. Avoid abrasive scrubs that can intensify irritation.
Who It’s For
This treatment is indicated for acne. It may also be used by adults seeking support for rough texture and fine lines as directed by a clinician. Do not use if you have known hypersensitivity to tretinoin or formulary components. People with very sensitive or eczema-prone skin should speak with a healthcare professional before use. If you are pregnant, planning pregnancy, or breastfeeding, ask your prescriber whether a different option is appropriate.
Dosage and Usage
Follow your prescriber’s directions and the official label. Common practice is to cleanse, pat skin dry, and apply a pea-sized amount to the entire affected area once daily at night. Spread a thin film over the face, avoiding eyes, lips, and mucous membranes. Start slowly if you are new to retinoids. Many routines begin with several nights per week, then increase as tolerated. Pair with a gentle moisturizer, and always use sunscreen in the morning.
Tips for comfort: wait 20 to 30 minutes after washing before application if you are sensitive; use a bland moisturizer before or after; and avoid combining with strong exfoliants, astringents, or alcohol-based toners unless your clinician recommends it. For more care pointers, see How To Treat Acne.
Do not apply to sunburned, windburned, or eczematous skin. If severe irritation occurs, pause and speak with your prescriber. Always defer to the official product information when uncertain.
Strengths and Forms
This cream is commonly available in 20 g tubes. Published strengths include 0.025% and 0.05%. Selection may vary by manufacturer and pharmacy.
- Cream base suitable for nightly facial use
- Standard tube for measured, pea-sized amounts
- Consult your prescriber if you need an alternative texture
Missed Dose and Timing
If you miss a dose, apply at the next regular time. Do not double up. Using more than directed will not speed results and can increase irritation. Establish a consistent nighttime routine and use sunscreen daily to support outcomes.
Storage and Travel Basics
Store at room temperature away from excessive heat and light. Keep the tube capped and out of reach of children and pets. When traveling, place it in a sealed bag to prevent leaks. Pack your current prescription details in case security or customs asks for documentation. If you are using other therapies that need special handling, your order will include temperature-controlled handling when required.
Benefits
Retinoid therapy can help keep pores clear, refine texture, and support a smoother-looking complexion. The cream format allows targeted facial coverage with a thin layer. Nightly use helps establish a steady routine. Many people find pairing the treatment with moisturizer improves comfort and supports adherence over time. For added learning, see What Helps With Acne Scars.
Side Effects and Safety
- Common effects: dryness, peeling, redness, tightness
- Less common: mild burning or stinging after application
- Sun sensitivity: increased risk of sunburn without protection
Serious reactions are uncommon but can include severe irritation, swelling, blistering, or allergic reactions. Stop use and seek medical care if you experience significant swelling, severe redness, or hives. Use caution with waxing or chemical hair removal on treated areas. With other acne agents like benzoyl peroxide, your prescriber may advise specific timing to reduce irritation.
Drug Interactions and Cautions
Topical retinoids can interact with other irritating skincare actives. Use care when combining with benzoyl peroxide, salicylic acid, alpha hydroxy acids, sulfur, or resorcinol. Photosensitizing medicines can amplify sun sensitivity. Discuss all skincare, over-the-counter products, and prescriptions with your clinician. Avoid unnecessary UV exposure and use daily sunscreen. Do not apply on open wounds, cuts, or eczema flares.
What to Expect Over Time
Improvement with a retinoid is gradual. Early weeks often focus on tolerability, with dryness and peeling more noticeable. Consistency, gentle cleansing, moisturization, and sun protection help maintain comfort. Your clinician may tailor your routine by adjusting frequency or supporting products. Stay the course and check in with your prescriber to align on goals and expectations.
Compare With Alternatives
If you prefer a different texture, a microsphere gel may feel lighter; see Retino A Micro Gel. For inflammatory acne with many red bumps, an oral option might be considered; ask your prescriber about Apprilon as part of a combination approach. Each option has distinct directions, tolerability, and monitoring needs.
Pricing and Access
Check current options and compare values across strengths and tubes. You can review Retino-A Cream price details and also see Tretinoin cream price information to plan your budget. We list transparent Canadian pricing, and orders Ships from Canada to US after prescription verification. If you are looking for savings, visit our Promotions page for current offers. Checkout uses encrypted processing to protect your data.
Availability and Substitutions
Stock may vary by strength and manufacturer. If the exact tube is unavailable, your prescriber may recommend a comparable tretinoin cream. Some patients compare formats and sizes before confirming. If you are comparing cash options, you can evaluate Tretinoin cream without insurance alongside other therapies.
Patient Suitability and Cost-Saving Tips
This therapy may suit adolescents and adults with comedonal or mixed acne. Very sensitive skin, active eczema, or frequent sun exposure may require adjustments or a different plan. Savings tips: consider multi-month fills if appropriate, align refills with routine check-ins, and use refill reminders so you do not run out. Keeping one tube for home and a travel-size skincare set can help you stay consistent.
Questions to Ask Your Clinician
- Starting plan: how often should I apply at first
- Layering: which cleanser and moisturizer pair best
- Combinations: can I use benzoyl peroxide or antibiotics with it
- Sun care: what SPF and reapplication routine should I follow
- Sensitivity: what signs mean I should pause and check in
- Goals: how will we assess progress and adjust
Authoritative Sources
FDA DailyMed: Tretinoin Topical
Health Canada Drug Product Database
Ready to proceed with your prescription? Order through Borderfreehealth for prompt, express shipping and US shipping from Canada. This page is informational and not a substitute for professional medical advice.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
How should I apply Retino-A Cream with my other skincare products?
Cleanse with a gentle, non-foaming wash, pat dry, then apply a pea-sized amount over the entire affected area at night. Wait a short period after washing if you are sensitive. Layer a bland moisturizer after the cream if needed. Use sunscreen every morning. Avoid combining with harsh scrubs, alcohol-based toners, or strong acids unless your clinician recommends them. Follow your prescriber’s directions and the official label for specific sequences.
Can I use makeup while starting this tretinoin treatment?
Yes, many patients use non-comedogenic makeup while on therapy. Apply the cream at night and makeup in the morning. Choose fragrance-free, oil-free products. Remove cosmetics gently to limit irritation. If you notice increased peeling, consider lighter coverage and moisturize more consistently. Speak with your clinician if irritation persists or you need personalized product suggestions.
What should I avoid when using this topical retinoid?
Avoid sunburn and tanning beds, and use daily sunscreen. Do not apply to broken or eczematous skin. Take care with waxing and harsh exfoliants, as they can increase irritation. Use caution when combining with benzoyl peroxide, salicylic acid, alpha hydroxy acids, sulfur, or resorcinol. Share all medicines and skincare with your prescriber so they can review for interactions and sensitivities.
Will my skin purge when starting this medicine?
Some users notice temporary flaking or increased visibility of clogged pores as turnover increases. This period can feel like “purging,” but experiences vary. Gentle skincare, moisturization, and consistent sunscreen can help with comfort. Your clinician may suggest adjusting frequency if sensitivity is high. Avoid picking, which can worsen marks. Check in with your prescriber if irritation is severe.
Can I use this cream during pregnancy or while breastfeeding?
Topical tretinoin is generally avoided in pregnancy. Discuss your situation with your clinician to determine appropriate options. If you are breastfeeding, ask about applying after a feed and avoiding infant contact with treated skin. Do not apply to the chest if nursing unless your prescriber confirms it is safe. Always follow professional advice and the product label.
How long until I see results with tretinoin?
Improvements tend to be gradual. Early use often focuses on tolerability and building a routine. Over time, regular nighttime application with sun protection can help reduce comedones and improve texture. Individual responses vary based on skin type, other products, and adherence. Your clinician can advise on expectations during follow-ups.
What should I do if my skin gets very irritated?
If you experience significant redness, burning, or swelling, pause and contact your clinician. They may recommend reducing frequency, adding a bland moisturizer, or changing your routine. Do not layer abrasive products. If severe reactions occur, seek medical care promptly. Follow the official label for guidance and use sunscreen daily to protect sensitive skin.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
How to book an appointment
- 1Create Begin by completing a profile or log into your existing account. This step ensures we have the necessary information to provide you with a service that's tailored to your needs. account and start earning.
- 2Scheduling an appointment with our online booking system is easy. Pick a day and time that suits you. You’ll receive an immediate confirmation, without the wait.
- 3Discuss your concerns and symptoms and receive a thorough diagnosis from one of our licensed doctors during a confidential video appointment.
- 4If you've been prescribed medication, your Rx is sent directly to one of our licensed pharmacies and delivered right to your door.
Get Started
To book an online doctor appointment, register for an account or login. After doing so, you can book your visit on this page.

