Stribild® Tablets for HIV-1 Treatment

This fixed-dose HIV-1 medicine combines four antivirals in one daily tablet. It is used as a complete regimen for adults and certain adolescents. This page explains how it works, who it may suit, and how you can arrange US delivery from Canada, including options if you are paying without insurance.

What Stribild Is and How It Works

Stribild® is a complete HIV-1 treatment. It contains an integrase inhibitor (elvitegravir), a pharmacoenhancer (cobicistat), and two nucleoside reverse transcriptase inhibitors (emtricitabine and tenofovir disoproxil fumarate). Together, these components help reduce viral replication and support immune recovery when taken as prescribed.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

It combines four medicines as Elvitegravir Cobicistat Emtricitabine Tenofovir DF tablets. Cobicistat boosts elvitegravir levels by inhibiting CYP3A enzymes, which helps maintain effective drug exposure. Emtricitabine and tenofovir DF work inside cells to block reverse transcriptase. This combination is a once-daily option and should not be taken with other HIV treatments.

For background on testing and diagnosis, see HIV Tests and our overview of modern regimens in HIV Treatment Trends. For condition resources, visit HIV.

Who It’s For

This treatment is indicated for adults and eligible adolescents living with HIV-1 who need a complete, once-daily regimen. It is generally used in people without known resistance to its components.

People with reduced kidney function, significant bone disease, or certain drug interaction risks may not be good candidates. It is not recommended during pregnancy due to lower elvitegravir exposures; clinicians may select a different regimen. Individuals co-infected with hepatitis B should be monitored closely, especially if the medicine is stopped, because hepatitis flares can occur.

Dosage and Usage

The standard schedule is one tablet by mouth once daily with food. Swallow whole; do not crush or split. Take it at the same time each day to support consistent levels.

The usual strength is Stribild 150/150/200/300 mg taken as a single daily tablet with a meal. After taking an exact-dose sentence, keep future doses at the label schedule unless your clinician advises otherwise. Do not combine this medicine with other antiretrovirals, boosters, or duplicate components. If antacids are needed, separate timing per label guidance.

See the official prescribing information for full directions if you have kidney or liver concerns, or if you take interacting medicines. Your clinician will advise on baseline and routine labs, including kidney function.

Strengths and Forms

This product is supplied as film-coated oral tablets. Availability may vary by pharmacy and market.

• Elvitegravir/Cobicistat/Emtricitabine/Tenofovir disoproxil 150/150/200/300 mg

Packaging, bottle counts, and manufacturer labeling can vary by origin. If a specific pack is unavailable, your prescriber may suggest a suitable alternative.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember with food, unless it is close to the time for your next dose. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. If you frequently miss doses, speak with your clinician about adherence supports.

Storage and Travel Basics

Store at room temperature in the original, tightly closed bottle with desiccant. Keep tablets dry and protected from excessive moisture. Always keep out of reach of children and pets.

When traveling, carry your medication in your hand luggage in the original labeled bottle, along with a copy of your prescription. Consider a simple pill organizer for daily use, and keep a small buffer supply when possible. For international trips, a medication list and prescriber contact can make security checks smoother.

Benefits

As a single-tablet regimen, Stribild tablets simplify daily management by combining four active drugs in one dose. This design can support adherence, which is essential for durable viral suppression. Many people appreciate predictable dosing with food and the absence of multiple separate bottles. The regimen is designed to be complete, so no additional antiretrovirals are added unless directed by a clinician.

Side Effects and Safety

Common effects may include nausea, diarrhea, headache, tiredness, dizziness, insomnia, and abnormal dreams. Some people notice mild rash or appetite changes. These are usually manageable and often improve with time.

Serious risks are uncommon but can occur. Important warnings include kidney problems (including Fanconi syndrome), decreases in bone mineral density, lactic acidosis and severe hepatomegaly with steatosis, and new or worsening liver issues, especially if you have hepatitis B or C. If therapy is stopped in people with chronic hepatitis B, severe flares can occur; clinicians monitor closely. Seek urgent care for signs of severe abdominal pain, persistent vomiting, yellowing of skin or eyes, breathing problems, or unusual weakness.

For support with HIV-related wasting, discuss separate therapies with your clinician; see Serostim for one such indication.

Drug Interactions and Cautions

Cobicistat is a strong CYP3A inhibitor and can raise levels of certain drugs. Some medicines are contraindicated, including strong enzyme inducers such as rifampin and specific anticonvulsants, select antiarrhythmics, certain sedatives, ergot derivatives, some statins, and St. John’s wort. Acid-reducing agents and antacids can affect integrase inhibitor absorption; follow label spacing guidance.

Use caution with nephrotoxic agents and NSAIDs. Do not use with other boosters or HIV regimens. Always tell your clinician and pharmacist about all prescription, over-the-counter, and herbal products you use.

What to Expect Over Time

With consistent daily use and regular follow-up, viral load typically declines and CD4 counts may improve. Your clinician will monitor labs, kidney function, and overall tolerability. If side effects occur, many are mild and transient. If lab results or interactions raise concerns, your regimen may be adjusted to maintain safety and control.

Adherence is key. Consider reminders, pairing doses with meals, and using a pill organizer. Regular check-ins help address questions early and support long-term outcomes.

Compare With Alternatives

Other complete or two-drug HIV regimens may be considered based on resistance profile, kidney health, and lifestyle. Your clinician may discuss integrase inhibitor–based options or NNRTI-based combinations. We also carry Pifeltro, an NNRTI used with NRTI backbones in certain patients. Explore broader options in Antivirals for context and availability.

Pricing and Access

Many patients look for Canadian pricing with reliable US shipping from Canada. We show transparent pharmacy options so you can review availability with your prescription. For savings opportunities, check our current Promotions.

Ask our team about Stribild price and ways to lower your out-of-pocket costs. You can view current pricing and place your order once your clinician has sent in a valid prescription. Checkout is secure, and your information is protected with encrypted processes.

For education about HIV care choices, you may also find these helpful: How You Get HIV and HIV AIDS Symptoms.

Availability and Substitutions

Stock can vary. If this product is temporarily unavailable, your prescriber may recommend a comparable, approved regimen that fits your clinical needs. We cannot guarantee restock dates. Your order team will communicate options that your clinician can review.

Patient Suitability and Cost-Saving Tips

This regimen may suit adults without significant kidney impairment and without known resistance to its components. It is not recommended during pregnancy, and it is not used with other HIV treatments. People with bone conditions, hepatitis B, or complex polypharmacy require extra review and monitoring.

• Multi-month fills: fewer refills, better adherence
• Refill reminders: stay on schedule
• Travel buffer: start requests early before trips
• Clinician check-ins: adjust plans if labs change
• Use one pharmacy: streamline interaction checks

We also support patients seeking Stribild without insurance by showing options that reflect Canadian pharmacy pricing. You can compare available packs and discuss alternatives with your clinician if needed.

Questions to Ask Your Clinician

• Is this a complete regimen for my HIV-1 history and resistance profile?
• Do I need baseline kidney and liver tests before starting?
• Which of my current medicines or supplements could interact?
• What should I do if I miss doses during travel or illness?
• How will we monitor bone health and vitamin D status?
• Is this regimen appropriate if I am pregnant or plan to become pregnant?
• What signs or symptoms mean I should contact you urgently?

Authoritative Sources

• FDA Prescribing Information
• Manufacturer Website
• Health Canada DPD

Ready to get started? Place your prescription with BorderFreeHealth for temperature-controlled handling when required and prompt, express shipping. Ships from Canada to US. Prescription required; content is for education and not a substitute for professional medical advice.