Salofalk® Suppositories for Ulcerative Proctitis

These are rectal mesalamine suppositories for inflammation limited to the rectum. They help relieve symptoms of ulcerative proctitis by delivering medicine where it is needed. This page explains how to use them safely, compares options, and shows access with US delivery from Canada, including considerations if you pay without insurance.

What Salofalk® Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Salofalk is a brand of mesalamine formulated for rectal use. Mesalamine rectal suppositories act locally in the rectum to help reduce inflammation associated with ulcerative proctitis. The active ingredient belongs to the 5-aminosalicylic acid class. It inhibits inflammatory pathways in the gut lining. This local action can lessen rectal bleeding, urgency, and discomfort.

Because the medicine works where symptoms occur, systemic exposure is typically lower than with many oral options. That can support tolerability for some patients. Your clinician will confirm that this rectal therapy fits your diagnosis and current treatment plan.

Who It’s For

This treatment is used for adults with mild to moderate ulcerative proctitis, as diagnosed by a healthcare professional. It may also be considered in select adolescents when a prescriber deems it appropriate. People with a known allergy to salicylates, such as aspirin, should avoid it. Those with severe kidney or liver problems should discuss risks carefully with their prescriber.

Salofalk rectal suppositories are not for treating infections, Crohn’s disease, or conditions outside the rectum. Tell your clinician about a history of myocarditis or pericarditis, pancreatitis, or blood disorders, as mesalamine products have been associated with rare reactions. Review all medicines and supplements you take, including over-the-counter pain relievers.

Dosage and Usage

Use this medicine exactly as directed on your prescription label. Many patients are instructed to use a suppository at bedtime after a bowel movement. Using it after emptying your bowels can improve contact time with the rectal lining. Wash and dry your hands before and after use. Remove the wrapper gently to avoid breaking the suppository. If it is too soft, briefly chill the foil-wrapped unit in a refrigerator, then unwrap and insert pointed end first.

Lie on your side, insert the suppository gently, and remain lying for several minutes to reduce the chance of expelling it. Try to avoid having a bowel movement for at least one hour after insertion. Treatment courses commonly last several weeks. Your prescriber may recommend a 1 g bedtime dose initially, then adjust the schedule based on your response. Always follow the official label and your clinician’s instructions.

Strengths and Forms

Availability may vary by pharmacy and region. Common presentations include:

• Rectal suppositories in 500 mg and 1 g strengths

Packaging and exact counts differ by manufacturer and country of origin. If a particular pack size is unavailable, your prescriber may adjust directions to match what is dispensed.

Missed Dose and Timing

If you miss a dose, use it when you remember unless it is almost time for the next one. If it is close to your next scheduled time, skip the missed dose and resume your regular schedule. Do not use two suppositories at once unless your prescriber specifically instructs it. For best results, be consistent with timing from day to day.

Storage and Travel Basics

Store in the original packaging, away from moisture and excessive heat. Keep out of reach of children and pets. Many rectal mesalamine products are kept at controlled room temperature and protected from light; check the package insert for specific instructions. Do not freeze. If a suppository becomes too soft to handle, chill the wrapped unit briefly to firm it before use.

When traveling, keep your medicines in carry-on luggage, in the original labeled box. Bring a copy of your prescription. If you are driving in hot weather, avoid storing the product in a car for extended periods. Our partners use temperature-controlled handling when required.

Benefits

This class treats inflammation directly at the site of symptoms. Local treatment can reduce rectal bleeding, mucus, and urgency associated with ulcerative proctitis. Many patients find bedtime use convenient. The treatment may be combined with other therapies if your prescriber recommends a step-up plan for disease control.

Side Effects and Safety

• Rectal discomfort or irritation
• Headache
• Nausea or abdominal pain
• Gas or bloating
• Constipation or diarrhea

Serious effects are uncommon but can include allergic reactions, worsening colitis, kidney problems, pancreatitis, or rare heart-related inflammation. Stop the medicine and seek care urgently for symptoms such as severe abdominal pain, chest pain, shortness of breath, swelling of the face or throat, or blood in urine. Your clinician may check kidney function before and during treatment, especially if you have risk factors.

Drug Interactions and Cautions

Tell your prescriber about all medicines you use. Combinations with azathioprine or 6-mercaptopurine can raise the risk of blood disorders; monitoring may be needed. Use caution with other nephrotoxic drugs. Discuss use with anticoagulants and antiplatelets, as additive bleeding risk can occur with salicylate-class agents. Report any history of salicylate sensitivity, kidney or liver disease, or peptic ulcers. Do not change doses or stop therapy without professional guidance.

What to Expect Over Time

Rectal symptoms may start to ease as inflammation calms with regular use. Many courses last a few weeks, and some patients transition to maintenance plans if needed. Your clinician will consider your endoscopic findings, symptom pattern, and history when deciding whether to continue, taper, or switch therapies. Keeping a simple symptom diary can help you and your clinician assess progress and tolerability.

Compare With Alternatives

Some patients use another 5-ASA rectal option such as Pentasa® Suppositories. Others may require a topical corticosteroid when 5-ASA alone is insufficient; an example is Uceris Rectal Foam. Your prescriber will match therapy to disease extent and activity. For broader background on disease categories and treatments, you can also review our Ulcerative Colitis and Gastrointestinal pages.

Pricing and Access

We list transparent options so you can compare choices and talk with your prescriber about fit. Many patients ask about the Salofalk suppositories price when evaluating therapy. Canadian pharmacy pricing can help reduce out-of-pocket costs for some users. Fulfilment Ships from Canada to US with a valid prescription. See current offers on our Promotions page, and learn more about paying out of pocket from our article How Much Do Prescription Drugs Cost Without Insurance.

Availability and Substitutions

Stock status can vary. If your product is unavailable, your prescriber may suggest an alternative or a comparable formulation. In some cases, Generic mesalamine suppositories may be appropriate if permitted by your prescriber and pharmacy. If a brand switch occurs, confirm the strength and directions before use.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with mild to moderate rectal disease who can tolerate local 5-ASA. It is not appropriate for those with salicylate allergy or specific contraindications noted by your clinician. Ask about multi-month fills to reduce total pharmacy visits, and set refill reminders so you have enough on hand during flares or travel. Patients paying cash can compare options and ask about the Salofalk suppositories cash price versus alternatives. Consider combining mail fulfilment with local care so your prescriber can monitor safety and response.

Questions to Ask Your Clinician

• Treatment goals: what symptom changes should I track?
• Dosing plan: bedtime only, or multiple times daily?
• Combining therapies: can I use oral mesalamine or foam if needed?
• Monitoring: will I need kidney labs or other checks?
• Safety: what signs mean I should stop and call you?
• Duration: how long before reassessing my regimen?
• Lifestyle: diet, stress, or routines that support remission?

Authoritative Sources

Dr. Falk Pharma (Manufacturer)DailyMed: Mesalamine Suppositories (US label)Health Canada Drug Product Database

Ready to get started? Place your order with prompt, express shipping and US shipping from Canada. This information is educational and not a substitute for professional medical advice. Always follow your prescriber’s guidance and the official label.