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Tradjenta® Tablets for Type 2 Diabetes
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$94.30
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Tradjenta® is linagliptin, a DPP-4 inhibitor used for adults with type 2 diabetes. It supports blood sugar control alone or alongside other therapies. You can review options without insurance, with US delivery from Canada.
What Tradjenta Is and How It Works
This medicine is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase incretin hormones, which can reduce hepatic glucose production and improve insulin release in response to meals. Linagliptin works throughout the day and can be taken with or without food. It is often combined with metformin or other antihyperglycemics if additional control is needed.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Many people use this treatment as part of a broader diabetes plan that may include nutrition, activity, and other agents. It is not for type 1 diabetes or diabetic ketoacidosis. Discuss your goals and monitoring plan with your healthcare professional, and follow the approved label for detailed instructions. For a broader overview of medicines used for this condition, you can read our Diabetes Drugs List and explore the Type 2 Diabetes category.
Who It’s For
This therapy is indicated for adults with type 2 diabetes to improve glycemic control as an adjunct to diet and exercise. It can be used as monotherapy or with agents such as metformin, SGLT2 inhibitors, thiazolidinediones, or basal insulin. People with a history of pancreatitis should use caution, and those with type 1 diabetes should not use this medicine.
If you have severe liver disease, discuss risks and benefits with your prescriber. Renal impairment usually does not require dose adjustment for this class, but individualized guidance belongs to your clinician. For context on insulin options that may be combined with oral agents, see Types Of Insulin and Lantus Insulin.
Dosage and Usage
The usual regimen is one tablet by mouth once daily. Label instructions indicate that Linagliptin 5 mg is the standard adult dose. Take it at the same time each day if possible. It may be taken with or without food, and tablets should be swallowed whole with water.
When used with insulin or sulfonylureas, the risk of low blood sugar can increase. Your care team may monitor for hypoglycemia. Keep a record of your readings and share them during follow-ups. For background on insulin resistance and how lifestyle may interact with medicines, visit Insulin Resistance.
Strengths and Forms
This product is available as film-coated oral tablets. Commonly supplied strength includes Tradjenta 5 mg tablets. Availability may vary by manufacturer and lot.
Missed Dose and Timing
If you miss a dose, take it when you remember the same day. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. Keeping a simple reminder can help maintain consistent use.
Storage and Travel Basics
Store tablets at room temperature in a dry place, in the original container with the label intact. Keep out of reach of children and pets. Avoid excess heat and humidity such as bathrooms or hot cars. When traveling, keep your medicine in your carry-on bag with copies of your prescription and your prescriber’s contact details. Pack a small pill organizer and set device reminders to stay on track.
If you use other diabetes supplies, check the manufacturer’s guidance for specific handling. Our checkout uses encrypted checkout for your security.
Benefits
This class can support glucose control without complex titration. Once-daily dosing is convenient for many people. It is generally weight-neutral and has a low risk of hypoglycemia when not paired with insulin or a sulfonylurea. It can be used with other oral agents if additional control is needed, following clinician guidance.
Side Effects and Safety
- Common effects: stuffy or runny nose, sore throat, cough
- Headache or mild joint pain
- Diarrhea or stomach discomfort
Serious but less common risks include pancreatitis, severe joint pain, or blistering skin reactions such as bullous pemphigoid. Stop the medicine and seek medical help if you develop severe abdominal pain that may radiate to the back, signs of an allergic reaction, or extensive skin blistering. Hypoglycemia can occur when combined with insulin or sulfonylureas; watch for shakiness, sweating, confusion, or dizziness.
Drug Interactions and Cautions
Strong inducers of P-gp/CYP3A4, such as rifampin, may reduce linagliptin exposure. Tell your prescriber about all prescription drugs, OTC products, and supplements. If you have pancreatic disease, heart failure, or significant hepatic disease, review risks and benefits before starting. Alcohol may increase the risk of low or high blood sugar depending on context; use caution and follow professional advice.
What to Expect Over Time
Most people take this therapy daily as part of a long-term plan. It may support a steadier glucose profile over time when combined with diet, activity, and ongoing monitoring. Keep regular appointments so your clinician can review labs, assess tolerability, and decide whether to continue, add, or change therapies. Daily routines, pill organizers, and phone reminders can help you stay consistent.
Compare With Alternatives
Other DPP-4 inhibitors may be considered depending on your history, goals, and tolerability. Two options we carry include Sitagliptin and Sitagliptin Malate. Your prescriber can advise which agent fits best with your broader treatment plan.
Pricing and Access
Compare Tradjenta price across pack sizes in your cart. You will see Canadian pricing with US delivery from Canada clearly shown at checkout. For general educational reading on insulin choices that may be paired with oral agents, see Types Of Insulin. If you are looking for site offers, visit our Promotions page.
For category browsing and broader options, explore Diabetes Care. Seasonal topics and prevention tips are available in Diabetes Month 2025.
Availability and Substitutions
Supply can vary by manufacturer and lot. If stock is limited, your prescriber may recommend a suitable alternative in the same class. If you are evaluating generics, ask about Tradjenta generic options and whether a substitution fits your plan. You can also review country-of-origin details in Canada.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults seeking a once-daily oral option, especially when weight neutrality and low hypoglycemia risk (as monotherapy) are priorities. It is not intended for type 1 diabetes or ketoacidosis. Ask your clinician about pairing with metformin or other classes if targets are not met. Consider multi-month supplies to reduce per-fill fees, and set refill reminders so you do not run out while traveling. Review your plan benefits and compare cash options at checkout.
For additional learning, see Diabetes Be Reversed and read about related care in Insulin Resistance. You can also browse practical guides in our articles and explore therapies within Diabetes Care.
Questions to Ask Your Clinician
- Starting goals: What A1C and fasting ranges should I aim for?
- Combination plan: Which medicines pair well with this therapy?
- Low blood sugar: What signs should I watch for and how should I respond?
- Kidney and liver checks: What monitoring do I need over time?
- Lifestyle fit: How should meals, activity, and alcohol be adjusted?
- Sick-day rules: What changes are recommended during illness?
- Travel prep: What documents and supplies should I carry?
Authoritative Sources
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How does this DPP-4 inhibitor help with blood sugar?
It increases levels of incretin hormones, which can stimulate insulin release from the pancreas in response to meals and decrease hepatic glucose production. The effect is glucose-dependent, meaning it works most when blood sugar is elevated and tends to have a lower hypoglycemia risk when used alone. Your clinician might combine it with metformin, SGLT2 inhibitors, or basal insulin based on your targets and tolerance. Monitoring and lifestyle measures remain important for long-term control.
Can I take it with metformin or insulin?
Yes, it is often used with metformin. It can also be combined with basal insulin or other oral agents when additional control is needed. When pairing with insulin or sulfonylureas, the chance of low blood sugar may increase, so your care team may recommend closer monitoring. Do not change doses on your own. Follow the approved label and your prescriber’s instructions for all medicines in your plan.
What are common side effects and serious warnings?
Common effects include upper respiratory symptoms such as runny nose or sore throat, as well as headache or mild stomach discomfort. Serious risks, though less common, include pancreatitis, severe joint pain, allergic reactions, and blistering skin reactions like bullous pemphigoid. If you develop severe abdominal pain, rash with blisters, or signs of anaphylaxis, seek urgent care. Report new symptoms to your healthcare professional promptly for assessment.
How should I take it each day?
Take one tablet by mouth once daily, at the same time each day, with or without food. Swallow the tablet whole with water. If you miss a dose, take it when you remember, unless it is close to your next scheduled dose. In that case, skip the missed dose and resume your regular schedule. Do not take two doses at once. Keep a log of doses and blood sugar readings to discuss at follow-up visits.
Do I need a dose change for kidney or liver problems?
Dose adjustments for kidney disease are generally not required for this medicine, but individual circumstances differ. People with significant hepatic impairment should review risks and benefits with their prescriber. Other agents in your plan might still need adjustment. Because decisions depend on labs, co-medications, and overall goals, rely on your clinician’s guidance and the official prescribing information for specifics.
What drug interactions should I know about?
Strong inducers such as rifampin can lower linagliptin levels and may reduce effectiveness. Always list all prescription medicines, OTC drugs, and supplements during visits. Alcohol may affect blood glucose in either direction depending on timing and food intake. Your healthcare professional will evaluate interactions across your entire regimen, including antihyperglycemics, blood pressure treatments, and lipid-lowering agents.
How should I store it and prepare for travel?
Keep tablets at room temperature in the original, labeled container, away from moisture and excess heat. Store out of reach of children and pets. When traveling, pack medicine in your carry-on, bring a copy of your prescription, and set reminders to maintain dosing time zones consistently. Consider a small pill organizer for convenience, and carry clinician contact details in case plans need to be adjusted while away.
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