Cuvposa

Cuvposa (glycopyrrolate oral solution) 1 mg/5 mL is a prescription anticholinergic medication used to reduce chronic severe drooling (sialorrhea) in paediatric patients aged 3 to 16 years with neurological conditions (such as cerebral palsy).

Benefits

• Reduces drooling by decreasing saliva production
• Improves comfort and quality of life for children with neurological conditions
• Oral liquid formulation allows for accurate dosing
• Cherry-flavored to improve taste and compliance
• Dosing can be adjusted gradually for best individual response

Dosage

• Starting dose: 0.02 mg/kg orally three times daily
• Dose can be increased by 0.02 mg/kg every 5 to 7 days based on tolerance and response
• Maximum dose: 0.1 mg/kg three times daily (not to exceed 1.5–3 mg per dose depending on body weight)
• Administer at least 1 hour before or 2 hours after meals
• Use a proper measuring device for accurate dosing

Warnings and Precautions

• Do not use in patients with glaucoma, urinary retention, severe ulcerative colitis, or certain gastrointestinal conditions
• May cause constipation, especially when increasing the dose
• May reduce sweating, increasing the risk of overheating
• Can cause drowsiness, dizziness, or blurred vision
• Use caution in patients with kidney problems or when combined with certain medications

Usage Instructions

• Shake well before use
• Use the provided oral syringe or dosing device
• Give at consistent times each day, separate from meals
• Do not exceed the prescribed dose
• Monitor for signs of side effects as the dose is increased

Storage Information

• Store at room temperature (20–25°C)
• Keep bottle tightly closed and protected from light
• Discard any unused solution 60 days after opening
• Keep out of reach of children

Side Effects

• Common: dry mouth, vomiting, constipation, flushing, nasal congestion, headache
• Other possible: decreased sweating, drowsiness, dizziness, blurred vision, appetite changes
• Serious (seek medical help): severe constipation, abdominal bloating, urinary retention, rapid heartbeat, confusion, signs of overheating such as fever and flushed skin