Please note: a valid prescription is required for all prescription medication.
Lisinopril Tablets for Hypertension
Buy More, Save More: Get 20% off when you buy 3 or more of any one product using code LESS20 at checkout.
Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
Black Friday Bonus: Enjoy free standard shipping on all orders over $250.
Offer can be combined with the 20% “Buy More, Save More” discount. Enter each coupon code separately at checkout to claim your offers. Offer ends December 5, 2025.
Price range: $74.99 through $99.99
Secure Encrypted Payments
Lisinopril is an ACE inhibitor used for high blood pressure and certain heart conditions. This page explains how it works, typical strengths, and safe-use basics, with US shipping from Canada for those paying without insurance.
What Lisinopril Is and How It Works
Generic lisinopril belongs to the angiotensin-converting enzyme inhibitor class. It blocks the conversion of angiotensin I to angiotensin II. This relaxes blood vessels and reduces the workload on the heart. Lower vascular resistance can help reduce blood pressure and protect the kidneys in appropriate patients.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This medicine may be used alone or with other blood pressure agents. It is typically taken once daily. Consistent daily use matters because steady ACE inhibition supports ongoing blood pressure control. Check the official label for complete details on use and risks.
Learn more about the class in our overview of ACE Inhibitors Guide, and see the related condition page for Hypertension.
Who It’s For
This treatment is prescribed for adults with hypertension. It is also used in certain patients with heart failure and to improve survival after some heart attacks, per labeling. People with a history of angioedema related to ACE inhibitors should avoid this therapy. It is not recommended during pregnancy due to potential fetal harm.
Those taking aliskiren for diabetes should not combine these agents. Patients with significant kidney artery narrowing or severe kidney impairment need careful evaluation. If you live with heart failure, see our condition resource on Heart Failure.
Dosage and Usage
Clinicians individualize dosing. Some adults start with Lisinopril 10 mg once daily for high blood pressure, then adjust based on response and tolerability. For heart failure or post–myocardial infarction use, lower starting doses are common, with careful titration from there. Swallow tablets with water. Take at the same time each day, with or without food, unless your prescriber advises differently.
If you also use a diuretic, dizziness can occur when starting or changing doses. Rise slowly from sitting or lying positions. Do not make dose changes on your own; follow your prescriber’s instructions and the official label.
Strengths and Forms
This medicine is available as oral tablets. Common strengths include 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg, and 40 mg. Availability can vary by manufacturer and lot. Some patients may recognize the legacy brand strength, such as Zestril 20 mg, though pharmacies dispense therapeutically equivalent generics when prescribed as such.
Color and shape differ by manufacturer. Always check your tablet imprint when you receive a refill and keep the Patient Information Leaflet for reference.
Missed Dose and Timing
If you miss a dose, take it when you remember on the same day. If it is near the time for your next dose, skip the missed dose. Resume your regular schedule the next day. Do not take extra tablets to make up a missed dose. If you are prescribed a Lisinopril 20 mg tablet and miss it repeatedly, discuss adherence strategies with your prescriber or pharmacist.
Storage and Travel Basics
Store tablets at room temperature in a dry place. Keep the bottle tightly closed and away from moisture and direct light. Use the original labeled container. Keep out of reach of children and pets. When traveling, carry your prescription label, a medication list, and enough tablets for your trip plus a small buffer. Pack in your carry-on to avoid lost luggage. Our parcels use temperature-controlled handling when required.
Benefits
This therapy can help lower blood pressure with once-daily dosing. It is available in several strengths, which can help prescribers tailor care. As a long-used ACE inhibitor, it may be combined with other classes when medically appropriate. Many patients appreciate the consistency of a tablet taken at the same time each day.
Side Effects and Safety
- Dry cough
- Dizziness or lightheadedness
- Headache
- Fatigue
- Nausea or upset stomach
Serious effects are uncommon but can include angioedema (swelling of the face, lips, tongue, or throat), severe hypotension, kidney problems, or high potassium. Seek urgent care for swelling, trouble breathing, fainting, or signs of an allergic reaction. This medicine carries warnings about fetal toxicity; do not use if pregnant, and tell your clinician if you become pregnant during therapy.
Drug Interactions and Cautions
Tell your prescriber about all medicines, vitamins, and herbal products you use. Important interactions include:
- Potassium supplements or potassium-sparing diuretics, which may increase potassium levels
- ARBs, aliskiren, or sacubitril/valsartan, which can overlap with ACE effects
- NSAIDs, which can affect kidney function when combined with ACE inhibitors
- Diuretics, which may raise the chance of dizziness when starting therapy
- Lithium, which can have increased levels
Limit alcohol, which can amplify blood pressure lowering. Monitor for dehydration during illness, especially if vomiting or diarrhea occurs. Your healthcare professional may order labs to check kidney function and potassium as needed.
What to Expect Over Time
Blood pressure improvement builds with consistent daily use. You may not feel different day to day, so checking readings helps track progress. Some people notice lightheadedness early on, which can lessen after the body adjusts. Ongoing follow-up helps confirm that the dose and any companion therapies remain appropriate.
Compare With Alternatives
Other ACE inhibitors may be options if your prescriber recommends a change. Ramipril is another once-daily agent used for hypertension and certain cardiac indications. Trandolapril is also used for blood pressure control and post–myocardial infarction care in select cases. Some patients previously used Prinivil 20 mg before moving to a generic equivalent; your prescriber can advise on comparable options.
For background on the class, see Captopril Uses or browse our category for ACE Inhibitors.
Pricing and Access
We present Canadian pharmacy options and US fulfilment. For cash-pay buyers, comparing tablets by strength and count can be helpful. Search the product page to see choices. If you are looking for Lisinopril price without insurance, you can review available packs and quantities before adding to cart. US orders typically Ships from Canada to US with tracking. Checkout uses encrypted processing.
You can select your quantity and submit your prescription during checkout. After your prescriber confirms the order, our partner pharmacy dispenses according to the script and the official label.
Availability and Substitutions
Supply can vary by manufacturer and strength. If a specific strength is temporarily unavailable, a prescriber may recommend another strength with adjusted tablet counts, or a therapeutic alternative from the same class. Combination therapy may be considered for some patients, such as a lisinopril and hydrochlorothiazide option, if your clinician feels it is appropriate.
Patient Suitability and Cost-Saving Tips
This therapy suits many adults with hypertension. It may not fit patients with prior ACE inhibitor–related angioedema, pregnancy, or certain kidney conditions. Discuss your medical history, current medicines, and any over-the-counter products with your clinician.
- Multi-month fills: Ask your prescriber if a longer supply is appropriate.
- Strength alignment: Using a higher-strength tablet split only if specifically directed.
- Refill reminders: Set phone alerts to help maintain adherence.
- Home monitoring: Keep a blood pressure log to support dose reviews.
- Travel-ready: Refill before trips and pack a small buffer.
Questions to Ask Your Clinician
- What blood pressure range should I aim for at home?
- How often should my kidney function and potassium be checked?
- Which symptoms mean I should call the office promptly?
- Could a diuretic or calcium-channel blocker be added if needed?
- Are there medicines or supplements I should avoid?
- What lifestyle steps best support this therapy?
Authoritative Sources
FDA DailyMed: Lisinopril Label
Health Canada Drug Product Database: Lisinopril
Zestril Prescribing Information
Ready to proceed? Add to cart when you are set. We offer prompt, express shipping with US delivery from Canada. This information is not a substitute for medical advice; always follow your prescriber and the official label.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
What is Lisinopril used for?
Lisinopril is an ACE inhibitor used to treat high blood pressure, heart failure, and to improve survival after a heart attack. It helps reduce the workload on the heart and prevents further damage to the cardiovascular system.
How does Lisinopril lower blood pressure?
It works by blocking the conversion of angiotensin I to angiotensin II, a chemical that narrows blood vessels. As a result, blood vessels relax, which lowers blood pressure and improves blood flow.
Can Lisinopril cause side effects?
Yes, common side effects include dizziness, dry cough, and headache. In rare cases, it can cause serious side effects such as angioedema (swelling of the face or throat) or kidney dysfunction, requiring immediate medical attention.
Should Lisinopril be taken at a specific time of day?
Lisinopril can be taken at any time but should be taken consistently at the same time each day. Taking it in the morning is common, especially to avoid nighttime drops in blood pressure that can cause dizziness.
Is it safe to use Lisinopril with diuretics?
Yes, but combining with diuretics like hydrochlorothiazide may increase the risk of low blood pressure or kidney issues. Doctors often prescribe the combination under close monitoring of electrolytes and renal function.
How long does it take to notice blood pressure changes?
Response varies. Some people see gradual improvements over the first few weeks of consistent daily dosing. You may not feel a change, so checking readings at home helps show progress. Your clinician may adjust therapy based on readings, labs, and tolerance. Keep taking the medicine as directed unless your prescriber advises a change. Do not stop suddenly without medical guidance.
Can I develop a cough while using this ACE inhibitor?
A dry, persistent cough can occur with ACE inhibitors. It may arise weeks or months after starting and can resolve after the medicine is changed. Other causes like allergies or infections may also lead to cough. Tell your healthcare professional if you notice a lingering cough, swelling, or trouble breathing. Seek urgent help for any signs of angioedema such as facial or throat swelling.
Is this safe to use if I have kidney disease?
ACE inhibitors can be helpful in some patients with kidney conditions, but they require monitoring. Your clinician may check creatinine and potassium before and after changes. Certain situations, like bilateral renal artery stenosis, need special caution. Avoid dehydration and discuss any NSAID use. Follow the plan your prescriber sets and review lab results regularly.
What should I avoid while taking it?
Tell your clinician about all medicines and supplements. Using potassium salt substitutes, potassium-sparing diuretics, or high-dose NSAIDs can raise risks. Alcohol may intensify blood pressure lowering. Some combinations like aliskiren in diabetes are not advised. Never start or stop companion medicines without consulting your prescriber or pharmacist.
Can I drink alcohol with this therapy?
Alcohol can increase the blood pressure–lowering effect and may make dizziness more likely, especially when starting or changing doses. If you drink, do so cautiously and avoid activities that need full alertness until you know your response. Discuss safe limits with your clinician, particularly if you take diuretics or other antihypertensives.
What happens if I miss a dose?
If you miss a dose, take it when remembered on the same day. If it is close to the next dose, skip the missed dose and resume the regular schedule. Do not double up. Using a pillbox, phone reminder, or calendar can help reduce missed doses. If you miss doses often, talk with your prescriber about strategies to stay on track.
Can I switch from another ACE inhibitor or an ARB?
Switching should be guided by your prescriber. The choice depends on your history, current readings, side effects, and coexisting conditions. Your clinician may recommend a washout period in some cases, especially if moving from sacubitril/valsartan. Do not overlap ACE inhibitors with ARBs without medical advice, and follow label-based directions during any transition.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
How to book an appointment
- 1Create Begin by completing a profile or log into your existing account. This step ensures we have the necessary information to provide you with a service that's tailored to your needs. account and start earning.
- 2Scheduling an appointment with our online booking system is easy. Pick a day and time that suits you. You’ll receive an immediate confirmation, without the wait.
- 3Discuss your concerns and symptoms and receive a thorough diagnosis from one of our licensed doctors during a confidential video appointment.
- 4If you've been prescribed medication, your Rx is sent directly to one of our licensed pharmacies and delivered right to your door.
Get Started
To book an online doctor appointment, register for an account or login. After doing so, you can book your visit on this page.

