Silenor® Tablets for Insomnia

Silenor is a low-dose doxepin tablet used to help adults stay asleep. It is a selective sleep maintenance treatment, not a daytime sedative. This page explains how it works, key safety points, and how to access Canadian options, including typical costs without insurance. Ships from Canada to US.

What Silenor Is and How It Works

Silenor® contains doxepin in low doses for sleep maintenance insomnia. At these doses, it primarily blocks histamine H1 receptors in the brain. That action can reduce nighttime awakenings and improve sleep continuity.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This effect is distinct from antidepressant doses of doxepin. The treatment is taken at bedtime and is designed to support sustained sleep. Learn about related condition details in our Insomnia resource.

Exact-match keyword: Silenor medication

Who It’s For

This medicine is for adults with difficulty maintaining sleep. It may be considered when sleep hygiene steps and non-drug measures are not enough. Children and adolescents are generally not candidates for this therapy.

People with severe urinary retention or untreated narrow-angle glaucoma should avoid it. Do not use with an MAOI or within 14 days of stopping one. Discuss liver problems, urinary issues, glaucoma history, bipolar disorder, or risk of sleep apnea with a healthcare professional.

Some patients with coexisting mental health needs may review broader options across our Mental Health category.

Exact-match keyword: Doxepin for sleep tablets

Dosage and Usage

Per labeling, adults typically take one tablet within 30 minutes of bedtime. Take on an empty stomach, allowing at least three hours after a meal to reduce next-day effects. Swallow whole with water.

A lower starting dose is often used in older adults. Avoid alcohol and other sedatives at night. Do not drive or perform tasks requiring alertness the next day until you know how this medicine affects you.

Only your prescriber can determine the appropriate schedule. Always follow the official product label and your clinician’s specific guidance.

Exact-match keyword: Silenor dosage

Strengths and Forms

This therapy is supplied as film-coated tablets in two strengths commonly referenced on labels. Availability can vary by manufacturer and country of origin.

• Doxepin tablets 3 mg
• Doxepin tablets 6 mg

Brand and generic presentations may differ in packaging and imprint. If you have questions about a particular manufacturer, speak with your prescriber or pharmacist.

Exact-match keyword: Doxepin tablets 3 mg

Missed Dose and Timing

If it is close to your normal wake time, skip the dose. Do not take another tablet in the middle of the night unless you can stay in bed for a full night’s rest. Do not double up to make up for a missed dose.

Taking it soon after a heavy or late meal can increase the risk of next-day drowsiness. Keep a regular bedtime routine to support effectiveness.

Exact-match keyword: Silenor tablets for sleep

Storage and Travel Basics

Store tablets at room temperature in the original, child-resistant container. Protect from excess moisture and light. Keep out of reach of children and pets.

When you travel, pack your medication in your carry-on, along with your prescription details. A simple medication list helps during security checks. Use a pill organizer only if you can keep tablets labeled. For longer trips, bring extra days of medicine in case of unexpected delays.

Some products require special handling; our systems use encrypted checkout and follow temperature-controlled handling when required.

Benefits

This medicine targets nighttime awakenings rather than sleep initiation. Many patients appreciate once-daily dosing at bedtime. The class has a different profile than controlled hypnotics.

It may help reduce fragmented sleep when taken as directed. Regular schedules and consistent routines can further support your sleep plan.

Side Effects and Safety

• Common: drowsiness, dry mouth, nausea
• Other: dizziness, fatigue, sore throat
• Less common: constipation, urinary hesitancy

Serious effects are uncommon at labeled doses, but can include urinary retention, worsening glaucoma, confusion, or mood changes. Seek urgent help for allergic reactions or new or worsening suicidal thoughts. Use caution with other drugs that cause sedation or have anticholinergic effects. Older adults may be more sensitive to side effects.

Exact-match keyword: Doxepin Silenor

If you experience next-day sleepiness, discuss timing and meals with your prescriber. Do not change your dose on your own.

Some patients explore non-drug strategies alongside medicine. For context, you can read our related article Mirtazapine For Sleep.

Drug Interactions and Cautions

Avoid use with MAOIs or within 14 days of stopping one. Combining with alcohol, benzodiazepines, opioids, or other sedatives can increase drowsiness and risks. Strong CYP2D6 inhibitors may raise doxepin levels.

Anticholinergics may increase dry mouth, constipation, and urinary issues. Use caution with drugs that affect heart rhythm. Always provide your full medication list, including over-the-counter sleep aids and supplements, to your prescriber.

For certain patients, alternatives such as Amitriptyline Tb may be discussed, based on history and tolerability.

What to Expect Over Time

Some people notice support for sleep maintenance on the first nights. Others describe gradual improvement with consistent bedtime use. Avoid heavy meals close to dosing and maintain a dark, quiet sleep environment.

Regular check-ins with your prescriber can help review benefits, next-day alertness, and ongoing need. If you wake for safety-sensitive responsibilities, discuss whether this therapy is appropriate.

Compare With Alternatives

For short-term sleep initiation problems, a non-benzodiazepine hypnotic such as Zolpidem may be considered. It works on GABA receptors and is typically used for difficulty falling asleep.

When insomnia coexists with low appetite or certain mood symptoms, clinicians sometimes consider Mirtazapine. Selection depends on your history, other medicines, and safety factors. Your prescriber will guide the choice.

Pricing and Access

Canadian pharmacy options can offer competitive cash-pay opportunities with US shipping from Canada. Compare choices, verify your prescription, and select a suitable refill plan.

You can review current offers on our Promotions page when available. Category browsing by origin is also possible under Canada.

Ask your prescriber about multi-month supplies to reduce fees and fewer checkouts. Talk with our team if you need help transferring an existing prescription.

Exact-match keyword: Silenor price

Availability and Substitutions

Stock can vary by manufacturer and strength. If a specific tablet is not available, your prescriber may recommend an equivalent doxepin formulation or a different sleep therapy. Pharmacy teams coordinate with your clinician before making any changes.

Brand and generic labels may differ by country. If you have questions about imprint or packaging, request photos before fulfilment.

Patient Suitability and Cost-Saving Tips

Good candidates include adults with sleep maintenance insomnia who can take a bedtime tablet and allow enough time for rest. This medicine may not suit people with severe urinary retention, uncontrolled glaucoma, or those using potent sedatives.

• Multi-month fills: ask about 60–90 days
• Refill reminders: set phone alerts
• Meal timing: avoid late heavy meals
• Medication list: share updates with your prescriber
• Travel kit: keep tablets and a copy of your prescription

If you need broader support, explore related topics in Mental Health to coordinate care across conditions.

Questions to Ask Your Clinician

• Am I a good candidate for low-dose doxepin?
• How should I time the dose with my evening meal?
• What signs mean I should stop and call you?
• Which medicines or supplements could interact?
• How long should I try this therapy before reassessing?
• Can I get a 60–90 day supply to reduce refill steps?
• What non-drug sleep strategies should I add?

Authoritative Sources

Ready when your prescription is? Place your order with Border Free Health for temperature-controlled handling when required and prompt, express shipping.

Disclaimer: This page summarizes publicly available label information. It is not medical advice. Always follow your prescriber’s instructions and the official package insert.